Chronic Neuroinflammation in Alzheimer’s Disease: New Perspectives on Animal Models and Promising Candidate Drugs

Pharmacological Treatment of Alzheimer Disease

(2017) Fadi Massoud et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

A Versatile High Throughput Screening System for the Simultaneous Identification of Anti-Inflammatory and Neuroprotective Compounds

(2017) Elizabeth Hansen et al.   JOURNAL OF ALZHEIMERS DISEASE

Curcumin Inhibits TLR2/4-NF-κB Signaling Pathway and Attenuates Brain Damage in Permanent Focal Cerebral Ischemia in Rats

(2014) Xian-kun Tu et al.   INFLAMMATION

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

(2013) Shashi Kant Tiwari et al.   ACS Nano

Clinical Trials in Predementia Stages of Alzheimer Disease

(2013) Jagan A. Pillai et al.   MEDICAL CLINICS OF NORTH AMERICA

Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model

(2013) Le Zhao et al.   MOLECULES

Vitamin D2-Enriched Button Mushroom (Agaricus bisporus) Improves Memory in Both Wild Type and APPswe/PS1dE9 Transgenic Mice

(2013) Louise Bennett et al.   PLoS One

Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation, mitochondrion protection and MAPK signal inactivation in an AD cell model

(2012) Le Zhao et al.   BRAIN RESEARCH

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain

(2012) Bernhard T Baune et al.   Journal of Neuroinflammation

Genetic insights in Alzheimer's disease

(2012) Karolien Bettens et al.   LANCET NEUROLOGY

Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease

(2012) Michel Grothe et al.   NEUROBIOLOGY OF AGING

Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice

(2012) Francisco J. Gil-Bea et al.   NEUROBIOLOGY OF DISEASE

Extended results of the Alzheimer’s disease anti-inflammatory prevention trial

(2011) John C. Breitner et al.   Alzheimers & Dementia

Assessing the contribution of inflammation in models of Alzheimer's disease: Figure 1

(2011) Hannah Johnston et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Single-channel Ca2+imaging implicates Aβ1–42 amyloid pores in Alzheimer’s disease pathology

(2011) Angelo Demuro et al.   JOURNAL OF CELL BIOLOGY

Role of Interleukin 6 and Alpha-Globulins in Differentiating Alzheimer and Vascular Dementias

(2011) Azza A. Helmy et al.   Neurodegenerative Diseases

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice

(2010) I. Goussakov et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of tau-induced neurodegeneration

(2009) Khalid Iqbal et al.   ACTA NEUROPATHOLOGICA

Amyloid precursor protein transgenic mouse models and Alzheimer's disease: Understanding the paradigms, limitations, and contributions

(2009) Tyler A. Kokjohn et al.   Alzheimers & Dementia

Reduction of Basal Forebrain Cholinergic System Parallels Cognitive Impairment in Patients at High Risk of Developing Alzheimer's Disease

(2009) M. Grothe et al.   CEREBRAL CORTEX

Alzheimer's disease: Seeing the signs early

(2009) Bennett P. Leifer   Journal of the American Academy of Nurse Practitioners

Activated astroglia during chronic inflammation in Alzheimer's disease—Do they neglect their neurosupportive roles?

(2009) Stacey Fuller et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease

(2009) Velandai Srikanth et al.   NEUROBIOLOGY OF AGING

Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease☆

(2008) Annette Maczurek et al.   ADVANCED DRUG DELIVERY REVIEWS

Inflammation and the Redox-sensitive AGE-RAGE Pathway as a Therapeutic Target in Alzheimer's Disease

(2008) Annette Maczurek et al.   Annals of the New York Academy of Sciences

Curcumin Supplementation Lowers TNF-α, IL-6, IL-8, and MCP-1 Secretion in High Glucose-Treated Cultured Monocytes and Blood Levels of TNF-α, IL-6, MCP-1, Glucose, and Glycosylated Hemoglobin in Diabetic Rats

(2008) Sushil K. Jain et al.   ANTIOXIDANTS & REDOX SIGNALING

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

(2008) Kavon Rezai-Zadeh et al.   Journal of Neuroinflammation

Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

(2008) A. N. Begum et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice model

(2007) Sang Keun Ha et al.   NEUROCHEMISTRY INTERNATIONAL