Autophagy in muscle regeneration: potential therapies for myopathies

Molecular mechanisms and physiological functions of mitophagy

(2021) Mashun Onishi et al.   EMBO JOURNAL

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

(2021) Shuxian Dong et al.   NATURE

Assessing Autophagy in Muscle Stem Cells

(2021) Silvia Campanario et al.   Frontiers in Cell and Developmental Biology

Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/β-catenin pathway

(2021) Bing Liu et al.   ANGIOGENESIS

Synergistic beneficial effects of natural activators of autophagy on endothelial cells and platelets

(2021) Roberto Carnevale et al.   BRITISH JOURNAL OF PHARMACOLOGY

MITOL promotes cell survival by degrading Parkin during mitophagy

(2021) Isshin Shiiba et al.   EMBO REPORTS

Muscle Stem Cell Quiescence: Controlling Stemness by Staying Asleep

(2021) Sara Ancel et al.   TRENDS IN CELL BIOLOGY

Membrane recruitment of Atg8 by Hfl1 facilitates turnover of vacuolar membrane proteins in yeast cells approaching stationary phase

(2021) Cheng-Wen He et al.   BMC BIOLOGY

ATG9A protects the plasma membrane from programmed and incidental permeabilization

(2021) Aurore Claude-Taupin et al.   NATURE CELL BIOLOGY

Machinery, regulation and pathophysiological implications of autophagosome maturation

(2021) Yan G. Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle : update 2021

(2021) Stephan Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors

(2020) Yuki Saito et al.   Nature Communications

Reductive stress impairs myogenic differentiation

(2020) Namakkal S. Rajasekaran et al.   Redox Biology

Autophagy and Stem Cells: Self-Eating for Self-Renewal

(2020) Natasha C. Chang   Frontiers in Cell and Developmental Biology

Autophagy: an essential but limited cellular process for timely skeletal muscle recovery from injury

(2020) Jarrod A. Call et al.   Autophagy

Trichoplein binds PCM 1 and controls endothelial cell function by regulating autophagy

(2020) Andrea Martello et al.   EMBO REPORTS

Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization

(2020) Jing Zhang et al.   Cell Metabolism

Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration

(2020) Shen’ao Zhou et al.   CELL RESEARCH

Myf6/MRF4 is a myogenic niche regulator required for the maintenance of the muscle stem cell pool

(2020) Felicia Lazure et al.   EMBO REPORTS

Structure, lipid scrambling activity and role in autophagosome formation of ATG9A

(2020) Shintaro Maeda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ischemia induces autophagy of endothelial cells and stimulates angiogenic effects in a hindlimb ischemia mouse model

(2020) In-Hye Jeong et al.   Cell Death & Disease

Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers

(2020) Matthieu Dos Santos et al.   Nature Communications

Damaged Myofiber-Derived Metabolic Enzymes Act as Activators of Muscle Satellite Cells

(2020) Yoshifumi Tsuchiya et al.   Stem Cell Reports

The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction

(2020) Samuele Metti et al.   Frontiers in Cell and Developmental Biology

The hypothalamic–pituitary–gonadal axis controls muscle stem cell senescence through autophagosome clearance

(2020) Ji‐Hoon Kim et al.   Journal of Cachexia Sarcopenia and Muscle

Cell therapy to improve regeneration of skeletal muscle injuries

(2019) Taimoor H. Qazi et al.   Journal of Cachexia Sarcopenia and Muscle

Stretching magnitude-dependent inactivation of AKT by ROS led to enhanced p53 mitochondrial translocation and myoblasts apoptosis

(2019) Song Jing et al.   MOLECULAR BIOLOGY OF THE CELL

Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation

(2019) Brittany L. Baechler et al.   Autophagy

Dynamic changes to lipid mediators support transitions among macrophage subtypes during muscle regeneration

(2019) Nikolas Giannakis et al.   NATURE IMMUNOLOGY

Therapeutic developments for Duchenne muscular dystrophy

(2019) Ingrid E. C. Verhaart et al.   Nature Reviews Neurology

Adult stem cells at work: regenerating skeletal muscle

(2019) Manuel Schmidt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Maigeng Zhou et al.   LANCET

The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration

(2019) David Sala et al.   Nature Communications

Guanine-rich RNA binding protein GRSF1 inhibits myoblast differentiation through repressing mitochondrial ROS production

(2019) Wenxin Yin et al.   EXPERIMENTAL CELL RESEARCH

Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration

(2019) David Hardy et al.   Skeletal Muscle

Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice

(2019) Anna S. Nichenko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy Defects in Skeletal Myopathies

(2019) Marta Margeta   Annual Review of Pathology-Mechanisms of Disease

In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy

(2018) Bojana Kravic et al.   Autophagy

PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol

(2018) Shiori Sekine et al.   BMC BIOLOGY

mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells

(2018) Amin Ardestani et al.   Cell Metabolism

Endothelial TFEB (Transcription Factor EB) Positively Regulates Postischemic AngiogenesisNovelty and Significance

(2018) Yanbo Fan et al.   CIRCULATION RESEARCH

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

(2018) Michael N. Wosczyna et al.   DEVELOPMENTAL CELL

Cargo recognition and degradation by selective autophagy

(2018) Damián Gatica et al.   NATURE CELL BIOLOGY

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Building and decoding ubiquitin chains for mitophagy

(2018) J. Wade Harper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal

(2018) Shantisree Sandeepani Rayagiri et al.   Nature Communications

Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury

(2018) Andrea Paolini et al.   Scientific Reports

Why is Skeletal Muscle Regeneration Impaired after Myonecrosis Induced by Viperid Snake Venoms?

(2018) José Gutiérrez et al.   Toxins

The AMPK/p27 Kip1 Axis Regulates Autophagy/Apoptosis Decisions in Aged Skeletal Muscle Stem Cells

(2018) James P. White et al.   Stem Cell Reports

Curcumin induces concentration-dependent alterations in mitochondrial function through ROS in C2C12 mouse myoblasts

(2018) Tianzheng Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The exerkine apelin reverses age-associated sarcopenia

(2018) Claire Vinel et al.   NATURE MEDICINE

Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease

(2018) Peter Feige et al.   Cell Stem Cell

Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis

(2018) Gabriele Civiletto et al.   EMBO Molecular Medicine

Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy

(2018) Kuo Zhang et al.   Nature Communications

Recycling of iron via autophagy is critical for the transition from glycolytic to respiratory growth

(2017) Tetsuro Horie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal muscle regeneration and impact of aging and nutrition

(2016) Carla Domingues-Faria et al.   AGEING RESEARCH REVIEWS

Mitochondrial maintenance via autophagy contributes to functional skeletal muscle regeneration and remodeling

(2016) Anna S. Nichenko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration

(2016) Alfonso Saera-Vila et al.   Autophagy

Proper autophagy is indispensable for angiogenesis during chick embryo development

(2016) Wen-hui Lu et al.   CELL CYCLE

Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles

(2016) E Fiacco et al.   CELL DEATH AND DIFFERENTIATION

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration

(2016) Micah T. Webster et al.   Cell Stem Cell

Regulatory T cells and skeletal muscle regeneration

(2016) Stefano Schiaffino et al.   FEBS Journal

Angiocrine functions of organ-specific endothelial cells

(2016) Shahin Rafii et al.   NATURE

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

(2016) Jun Wei et al.   NATURE IMMUNOLOGY

Proliferation of Human Primary Myoblasts Is Associated with Altered Energy Metabolism in Dependence on Ageing In Vivo and In Vitro

(2016) Reedik Pääsuke et al.   Oxidative Medicine and Cellular Longevity

The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis

(2016) P Fortini et al.   Cell Death & Disease

Impaired macrophage autophagy induces systemic insulin resistance in obesity

(2016) Young-Ho Kang et al.   Oncotarget

Comparative Study of Injury Models for Studying Muscle Regeneration in Mice

(2016) David Hardy et al.   PLoS One

Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts

(2015) Jon Sin et al.   Autophagy

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

PINK1-Parkin-Mediated Mitophagy Protects Mitochondrial Integrity and Prevents Metabolic Stress-Induced Endothelial Injury

(2015) Weiwei Wu et al.   PLoS One

Autophagy is required and protects against apoptosis during myoblast differentiation

(2014) Elliott M. McMillan et al.   BIOCHEMICAL JOURNAL

Receptor-mediated mitophagy in yeast and mammalian systems

(2014) Lei Liu et al.   CELL RESEARCH

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

(2014) Ann H Tang et al.   EMBO JOURNAL

Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function

(2014) Kristin P. Bibee et al.   FASEB JOURNAL

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert

(2014) Joseph T. Rodgers et al.   NATURE

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Muscle injury: Review of experimental models

(2013) Jaqueline de Souza et al.   JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

(2013) Takehiro Torisu et al.   NATURE MEDICINE

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions

(2012) A. Jacquel et al.   BLOOD

Induction of autophagy is essential for monocyte-macrophage differentiation

(2012) Y. Zhang et al.   BLOOD

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

IL-10 Triggers Changes in Macrophage Phenotype That Promote Muscle Growth and Regeneration

(2012) B. Deng et al.   JOURNAL OF IMMUNOLOGY

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A

(2011) Virginie Carmignac et al.   HUMAN MOLECULAR GENETICS

High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury

(2011) Ulka Sachdev et al.   JOURNAL OF VASCULAR SURGERY

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Normal myogenesis and increased apoptosis in myotonic dystrophy type-1 muscle cells

(2010) E Loro et al.   CELL DEATH AND DIFFERENTIATION

MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3

(2010) Hiroyuki Hirai et al.   JOURNAL OF CELL BIOLOGY

Can muscle regeneration fail in chronic inflammation: a weakness in inflammatory myopathies?

(2010) I. Loell et al.   JOURNAL OF INTERNAL MEDICINE

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Regulation of mitochondrial biogenesis during myogenesis

(2009) A.H.V. Remels et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY