Disulfide Cross-linking of a Multidrug and Toxic Compound Extrusion Transporter Impacts Multidrug Efflux

Structures of multidrug and toxic compound extrusion transporters and their mechanistic implications

(2015) Min Lu   Channels

Structural basis for the blockade of MATE multidrug efflux pumps

(2015) Martha Radchenko et al.   Nature Communications

STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel

(2014) Aparna Gudlur et al.   Nature Communications

Na+–Substrate Coupling in the Multidrug Antiporter NorM Probed with a Spin-Labeled Substrate

(2013) P. Ryan Steed et al.   BIOCHEMISTRY

Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

(2013) Yoshiki Tanaka et al.   NATURE

Structural insights into H+-coupled multidrug extrusion by a MATE transporter

(2013) Min Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of a Na+-coupled, substrate-bound MATE multidrug transporter

(2013) M. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cysteine Cross-linking Defines the Extracellular Gate for theLeishmania donovaniNucleoside Transporter 1.1 (LdNT1.1)

(2012) Raquel Valdés et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a presenilin family intramembrane aspartate protease

(2012) Xiaochun Li et al.   NATURE

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP

(2012) Camilo Perez et al.   NATURE

Structure of a cation-bound multidrug and toxic compound extrusion transporter

(2010) Xiao He et al.   NATURE

Ligand Effects on Cross-linking Support a Conformational Mechanism for Serotonin Transport

(2009) Zhen Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transport mechanism of a bacterial homologue of glutamate transporters

(2009) Nicolas Reyes et al.   NATURE

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Multidrug efflux transporters in the MATE family

(2008) Teruo Kuroda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS