Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

Structures of a Na+-coupled, substrate-bound MATE multidrug transporter

(2013) M. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform-Selective Inhibitors

(2012) Yuuki Hayashi et al.   ACS Chemical Biology

Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER

(2012) Oliver S. Smart et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Discovery of Macrocyclic Peptides Armed with a Mechanism-Based Warhead: Isoform-Selective Inhibition of Human Deacetylase SIRT2

(2012) Jumpei Morimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ribosomal production and in vitro selection of natural product-like peptidomimetics: The FIT and RaPID systems

(2012) Christopher J Hipolito et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library

(2011) Yusuke Yamagishi et al.   CHEMISTRY & BIOLOGY

Effects of a MATE Protein Inhibitor, Pyrimethamine, on the Renal Elimination of Metformin at Oral Microdose and at Therapeutic Dose in Healthy Subjects

(2011) H Kusuhara et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Lipidic cubic phase technologies for membrane protein structural studies

(2011) Vadim Cherezov   CURRENT OPINION IN STRUCTURAL BIOLOGY

Interactions of Tyrosine Kinase Inhibitors with Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Proteins

(2011) T. Minematsu et al.   MOLECULAR CANCER THERAPEUTICS

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Potent and Specific Inhibition of mMate1-Mediated Efflux of Type I Organic Cations in the Liver and Kidney by Pyrimethamine

(2010) S. Ito et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Structure of a cation-bound multidrug and toxic compound extrusion transporter

(2010) Xiao He et al.   NATURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

(2009) M. L. Becker et al.   DIABETES

The ID23-2 structural biology microfocus beamline at the ESRF

(2009) David Flot et al.   JOURNAL OF SYNCHROTRON RADIATION

Ins and Outs of Major Facilitator Superfamily Antiporters

(2008) Christopher J. Law et al.   Annual Review of Microbiology

SnBversion 2.3: triplet sieve phasing for centrosymmetric structures

(2008) Hongliang Xu et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY