STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel
Authors
Keywords
-
Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-10-09
DOI
10.1038/ncomms6164
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Emerging roles of store-operated Ca2+entry through STIM and ORAI proteins in immunity, hemostasis and cancer
- (2013) Wolfgang Bergmeier et al. Channels
- The Extended Transmembrane Orai1 N-terminal (ETON) Region Combines Binding Interface and Gate for Orai1 Activation by STIM1
- (2013) Isabella Derler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential Roles of the C and N Termini of Orai1 Protein in Interacting with Stromal Interaction Molecule 1 (STIM1) for Ca2+Release-activated Ca2+(CRAC) Channel Activation
- (2013) Hongying Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels
- (2013) Beth A. McNally et al. JOURNAL OF PHYSIOLOGY-LONDON
- An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry
- (2013) Sonia Sharma et al. NATURE
- Initial activation of STIM1, the regulator of store-operated calcium entry
- (2013) Yubin Zhou et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Pore waters regulate ion permeation in a calcium release-activated calcium channel
- (2013) H. Dong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Orai Channel Pore Properties and Gating by STIM: Implications from the Orai Crystal Structure
- (2013) B. S. Rothberg et al. Science Signaling
- STIM proteins: dynamic calcium signal transducers
- (2012) Jonathan Soboloff et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Crystal Structure of the Calcium Release-Activated Calcium Channel Orai
- (2012) X. Hou et al. SCIENCE
- Glu106in the Orai1 pore contributes to fast Ca2+-dependent inactivation and pH dependence of Ca2+release-activated Ca2+(CRAC) current
- (2011) Nathan R. Scrimgeour et al. BIOCHEMICAL JOURNAL
- Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating
- (2011) Judith Bergsmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91
- (2011) S. L. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI
- (2010) Patrick G. Hogan et al. Annual Review of Immunology
- The role of store-operated calcium influx in skeletal muscle signaling
- (2010) Jonathan A. Stiber et al. CELL CALCIUM
- A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating
- (2010) Annette Lis et al. JOURNAL OF GENERAL PHYSIOLOGY
- Pore architecture of the ORAI1 store-operated calcium channel
- (2010) Y. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1
- (2009) Chan Young Park et al. CELL
- CRAC channels and Ca2+signaling in mast cells
- (2009) Joseph Di Capite et al. IMMUNOLOGICAL REVIEWS
- ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+entry in the immune system and beyond
- (2009) Stefan Feske IMMUNOLOGICAL REVIEWS
- STIM1 gates the store-operated calcium channel ORAI1 in vitro
- (2009) Yubin Zhou et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural determinants of ion permeation in CRAC channels
- (2009) Beth A. McNally et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamic Coupling of the Putative Coiled-coil Domain of ORAI1 with STIM1 Mediates ORAI1 Channel Activation
- (2008) Martin Muik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy
- (2008) Laura Navarro-Borelly et al. JOURNAL OF PHYSIOLOGY-LONDON
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More