Oral Microbiota-Driven Cell Migration in Carcinogenesis and Metastasis

p53 directs leader cell behavior, migration, and clearance during epithelial repair

(2022) Kasia Kozyrska et al.   SCIENCE

Role of Porphyromonas gingivalis in oral and orodigestive squamous cell carcinoma

(2022) Richard J. Lamont et al.   PERIODONTOLOGY 2000

Reductionist Three-Dimensional Tumor Microenvironment Models in Synthetic Hydrogels

(2022) Rachel R. Katz et al.   Cancers

The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems

(2021) Susan E. Leggett et al.   Cell Communication and Signaling

Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host

(2021) George Hajishengallis et al.   PERIODONTOLOGY 2000

Regulation of olfactomedin 4 by Porphyromonas gingivalis in a community context

(2021) Zackary R. Fitzsimonds et al.   ISME Journal

sRNA23392 packaged by Porphyromonas gingivalis outer membrane vesicles promotes oral squamous cell carcinomas migration and invasion by targeting desmocollin‐2

(2021) Dongjuan Liu et al.   Molecular Oral Microbiology

Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis

(2021) Arpita Datta et al.   Cancers

Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development

(2021) Jeffrey D. Amack   Cell Communication and Signaling

Cancer cell metabolic plasticity in migration and metastasis

(2021) Jenna A. Mosier et al.   CLINICAL & EXPERIMENTAL METASTASIS

Cytokeratin 7 expression as a predictor of an unfavorable prognosis in colorectal carcinoma

(2021) Jan Hrudka et al.   Scientific Reports

Conversion from epithelial to partial-EMT phenotype by Fusobacterium nucleatum infection promotes invasion of oral cancer cells

(2021) Wenhua Shao et al.   Scientific Reports

A bacterial tyrosine phosphatase modulates cell proliferation through targeting RGCC

(2021) Chengcheng Liu et al.   PLoS Pathogens

Fusobacterium nucleatum Acts as a Pro-carcinogenic Bacterium in Colorectal Cancer: From Association to Causality

(2021) Shuang Wang et al.   Frontiers in Cell and Developmental Biology

Born to Run? Diverse Modes of Epithelial Migration

(2021) Pengfei Lu et al.   Frontiers in Cell and Developmental Biology

IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling

(2021) Tian-Hao Li et al.   CELLULAR ONCOLOGY

Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD

(2020) Madeleine C. McNeill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

From Beyond the Pale to the Pale Riders: The Emerging Association of Bacteria with Oral Cancer

(2020) Z.R. Fitzsimonds et al.   JOURNAL OF DENTAL RESEARCH

The multifarious regulation of the apical junctional complex

(2020) Alexandra D. Rusu et al.   Open Biology

Fusobacterium nucleatum promotes colorectal cancer metastasis by modulating KRT7-AS/KRT7

(2020) Shujie Chen et al.   Gut Microbes

The Human Oral Microbiome in Health and Disease: From Sequences to Ecosystems

(2020) Jesse R. Willis et al.   Microorganisms

Long-Range and Directional Allostery of Actin Filaments Plays Important Roles in Various Cellular Activities

(2020) Kiyotaka Tokuraku et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Salivary Mycobiome Contains 2 Ecologically Distinct Mycotypes

(2020) B.Y. Hong et al.   JOURNAL OF DENTAL RESEARCH

Inflammatory Networks Linking Oral Microbiome with Systemic Health and Disease

(2020) S.E. Kleinstein et al.   JOURNAL OF DENTAL RESEARCH

Porphyromonas gingivalis Promotes the Proliferation and Migration of Esophageal Squamous Cell Carcinoma through the miR-194/GRHL3/PTEN/Akt Axis

(2020) Gaofeng Liang et al.   ACS Infectious Diseases

EMT, MET, Plasticity, and Tumor Metastasis

(2020) Basil Bakir et al.   TRENDS IN CELL BIOLOGY

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

(2020) Lishay Parhi et al.   Nature Communications

Porphyromonas gingivalis promotes progression of esophageal squamous cell cancer via TGFβ-dependent Smad/YAP/TAZ signaling

(2020) Yi-Jun Qi et al.   PLOS BIOLOGY

Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

(2020) Pachiyappan Kamarajan et al.   PLoS Pathogens

The Oral Microbiome and Cancer

(2020) Muhammad Irfan et al.   Frontiers in Immunology

Involvement of Actin and Actin-Binding Proteins in Carcinogenesis

(2020) Magdalena Izdebska et al.   Cells

Increased Lamin B1 Levels Promote Cell Migration by Altering Perinuclear Actin Organization

(2020) Andrea Fracchia et al.   Cells

Proteomic characterization of outer membrane vesicles from gut mucosa-derived fusobacterium nucleatum

(2019) Jinjing Liu et al.   Journal of Proteomics

Snail-induced claudin-11 prompts collective migration for tumour progression

(2019) Ching-Fei Li et al.   NATURE CELL BIOLOGY

Identification of Potential Candidate Genes of Oral Cancer in Response to Chronic Infection With Porphyromonas gingivalis Using Bioinformatical Analyses

(2019) Fengxue Geng et al.   Frontiers in Oncology

Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

(2019) Stephen S. Dominy et al.   Science Advances

Real-time in vivo imaging of subpopulations of circulating tumor cells using antibody conjugated quantum dots

(2019) Chiung Wen Kuo et al.   JOURNAL OF NANOBIOTECHNOLOGY

Periodontal pathogens are a risk factor of oral cavity squamous cell carcinoma, independent of tobacco and alcohol and human papillomavirus

(2019) Ian Ganly et al.   INTERNATIONAL JOURNAL OF CANCER

International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis

(2019) Alasdair J Scott et al.   GUT

Stimulation with Porphyromonas gingivalis enhances malignancy and initiates anoikis resistance in immortalized oral keratinocytes

(2019) T. Hoppe et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Porphyromonas gingivalis lipopolysaccharide activates platelet Cdc42 and promotes platelet spreading and thrombosis

(2019) Vincent Senini et al.   JOURNAL OF PERIODONTOLOGY

Streptococcus gordonii programs epithelial cells to resist ZEB2 induction by Porphyromonas gingivalis

(2019) Jun Ohshima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

(2019) Varsha Prakash et al.   Nature Communications

Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors

(2019) Kyra Campbell et al.   Nature Communications

Imaging Cell-Matrix Adhesions and Collective Migration of Living Cells by Electrochemiluminescence Microscopy

(2019) Hao Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nesprin-1 impact on tumorigenic cell phenotypes

(2019) Ilknur Sur-Erdem et al.   MOLECULAR BIOLOGY REPORTS

Role of ACTN4 in Tumorigenesis, Metastasis, and EMT

(2019) Dmitri Tentler et al.   Cells

Multicellular scale front-to-rear polarity in collective migration

(2019) Lavinia Capuana et al.   CURRENT OPINION IN CELL BIOLOGY

Human oral microbiota and its modulation for oral health

(2018) Yangheng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration

(2018) Nicole M. Aiello et al.   DEVELOPMENTAL CELL

DNA Damage, Mutagenesis and Cancer

(2018) Ashis Basu   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Potential role of periodontal pathogens in compromising epithelial barrier function by inducing epithelial-mesenchymal transition

(2018) A. A. Abdulkareem et al.   JOURNAL OF PERIODONTAL RESEARCH

OUP accepted manuscript

(2018)   TOXICOLOGICAL SCIENCES

Intravital microscopy in the study of the tumor microenvironment: from bench to human application

(2018) Emmanuel M. Gabriel et al.   Oncotarget

Porphyromonas gingivalis traffics into endoplasmic reticulum-rich-autophagosomes for successful survival in human gingival epithelial cells

(2018) Kyulim Lee et al.   Virulence

HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression

(2018) Alix Warburton et al.   PLoS Genetics

HPV16 E6 promotes cervical cancer cell migration and invasion by downregulation of NHERF1

(2018) Qiqi Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Signaling by Discoidin Domain Receptor 1 in Cancer Metastasis

(2018) Mayur Gadiya et al.   Cell Adhesion & Migration

Non-redundant functions of EMT transcription factors

(2018) Marc P. Stemmler et al.   NATURE CELL BIOLOGY

The oral microbiota: dynamic communities and host interactions

(2018) Richard J. Lamont et al.   NATURE REVIEWS MICROBIOLOGY

EMT Transition States during Tumor Progression and Metastasis

(2018) Ievgenia Pastushenko et al.   TRENDS IN CELL BIOLOGY

Rho GTPase signaling complexes in cell migration and invasion

(2017) Campbell D. Lawson et al.   JOURNAL OF CELL BIOLOGY

Matrix degradability controls multicellularity of 3D cell migration

(2017) Britta Trappmann et al.   Nature Communications

Periodontal pathogens promote epithelial-mesenchymal transition in oral squamous carcinoma cells in vitro

(2017) A. A. Abdulkareem et al.   Cell Adhesion & Migration

Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement

(2017) Haibo Wang et al.   Oncotarget

Persistent Exposure to Porphyromonas gingivalis Promotes Proliferative and Invasion Capabilities, and Tumorigenic Properties of Human Immortalized Oral Epithelial Cells

(2017) Fengxue Geng et al.   Frontiers in Cellular and Infection Microbiology

Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis

(2017) Jungnam Lee et al.   Frontiers in Cellular and Infection Microbiology

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay

(2017) Jean-Baptiste Guy et al.   Jove-Journal of Visualized Experiments

Candida and Porphyromonas gingivalis: the effect on wound closure in vitro

(2017) Thijs M. Haverman et al.   Journal of Oral Microbiology

Engineered Models of Confined Cell Migration

(2016) Colin D. Paul et al.   Annual Review of Biomedical Engineering

Cellular Biophysics

(2016) Rick Horwitz   BIOPHYSICAL JOURNAL

Epithelial-mesenchymal transition in tissue repair and fibrosis

(2016) Rivka C. Stone et al.   CELL AND TISSUE RESEARCH

Porphyromonas gingivalisinitiates a mesenchymal-like transition through ZEB1 in gingival epithelial cells

(2016) Maryta N. Sztukowska et al.   CELLULAR MICROBIOLOGY

Porphyromonas gingivalis increases the invasiveness of oral cancer cells by upregulating IL-8 and MMPs

(2016) Na Hee Ha et al.   CYTOKINE

CCAT1: an oncogenic long noncoding RNA in human cancers

(2016) Xiaoqiang Guo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

FERMT1 mediates epithelial–mesenchymal transition to promote colon cancer metastasis via modulation of β-catenin transcriptional activity

(2016) C-C Liu et al.   ONCOGENE

α-Actinin-4 induces the epithelial-to-mesenchymal transition and tumorigenesis via regulation of Snail expression and β-catenin stabilization in cervical cancer

(2016) H-T An et al.   ONCOGENE

A collective route to metastasis: Seeding by tumor cell clusters

(2016) K. J. Cheung et al.   SCIENCE

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

HPV-16 E6/E7 promotes cell migration and invasion in cervical cancer via regulating cadherin switch in vitro and in vivo

(2015) Dongxiao Hu et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Modes of cancer cell invasion and the role of the microenvironment

(2015) Andrew G Clark et al.   CURRENT OPINION IN CELL BIOLOGY

Noncanonical Activation of β-Catenin by Porphyromonas gingivalis

(2015) Yun Zhou et al.   INFECTION AND IMMUNITY

Involvement of protease-activated receptor 4 in over-expression of matrix metalloproteinase 9 induced by Porphyromonas gingivalis

(2015) Hiroaki Inaba et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Locally excitable Cdc42 signals steer cells during chemotaxis

(2015) Hee Won Yang et al.   NATURE CELL BIOLOGY

Control of cell–cell forces and collective cell dynamics by the intercellular adhesome

(2015) Elsa Bazellières et al.   NATURE CELL BIOLOGY

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

(2015) Sara Lovisa et al.   NATURE MEDICINE

Prolonged and repetitive exposure to Porphyromonas gingivalis increases aggressiveness of oral cancer cells by promoting acquisition of cancer stem cell properties

(2015) Na Hee Ha et al.   TUMOR BIOLOGY

Elevated Serum Gas6 Is a Novel Prognostic Biomarker in Patients with Oral Squamous Cell Carcinoma

(2015) Tao Jiang et al.   PLoS One

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface

(2014) P Bronsert et al.   JOURNAL OF PATHOLOGY

Effect of Bacteria on the Wound Healing Behavior of Oral Epithelial Cells

(2014) Rupa Bhattacharya et al.   PLoS One

Oral Bacteria and Cancer

(2014) Sarah E. Whitmore et al.   PLoS Pathogens

Porphyromonas gingivalispromotes invasion of oral squamous cell carcinoma through induction of proMMP9 and its activation

(2013) Hiroaki Inaba et al.   CELLULAR MICROBIOLOGY

A conserved C-terminal sequence of high-risk cutaneous beta-human papillomavirus E6 proteins alters localization and signalling of  1-integrin to promote cell migration

(2013) A. Holloway et al.   JOURNAL OF GENERAL VIROLOGY

The Influence of Oral Bacteria on Epithelial Cell MigrationIn Vitro

(2013) Alexa M. G. A. Laheij et al.   MEDIATORS OF INFLAMMATION

Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer-systematic review and meta-analysis of trends by time and region

(2012) Hisham Mehanna et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

N-cadherin-mediated cell-cell adhesion promotes cell migration in a three-dimensional matrix

(2012) W. Shih et al.   JOURNAL OF CELL SCIENCE

Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer

(2012) Jian-Mei Hou et al.   JOURNAL OF CLINICAL ONCOLOGY

Epithelial to mesenchymal transition (EMT) biomarkers – E-cadherin, beta-catenin, APC and Vimentin – in oral squamous cell carcinogenesis and transformation

(2012) S.Y. Chaw et al.   ORAL ONCOLOGY

Quantitative Analysis of Random Migration of Cells Using Time-lapse Video Microscopy

(2012) Prachi Jain et al.   Jove-Journal of Visualized Experiments

Lipoxin A4InhibitsPorphyromonas gingivalis-Induced Aggregation and Reactive Oxygen Species Production by Modulating Neutrophil-Platelet Interaction and CD11b Expression

(2011) Emma Börgeson et al.   INFECTION AND IMMUNITY

The effects and mechanisms of blockage of STAT3 signaling pathway on IL-6 inducing EMT in human pancreatic cancer cells in vitro

(2011) C. HUANG et al.   NEOPLASMA

Cytokeratin 7 and cytokeratin 20 expression in colorectal adenocarcinomas

(2011) Reyhan Bayrak et al.   PATHOLOGY RESEARCH AND PRACTICE

Microfabricated Physical Spatial Gradients for Investigating Cell Migration and Invasion Dynamics

(2011) Michael Mak et al.   PLoS One

Nicotinamide N -methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells

(2010) Sai-Wen Tang et al.   CARCINOGENESIS

Involvement of the Wnt-β-catenin pathway in invasion and migration of oral squamous carcinoma cells

(2010) Iwai   INTERNATIONAL JOURNAL OF ONCOLOGY

Snail

(2010) Yadi Wu et al.   Cell Adhesion & Migration

Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

(2009) S. Pinner et al.   CANCER RESEARCH

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Two-photon imaging of effector T-cell behavior: lessons from a tumor model

(2008) Lai Guan Ng et al.   IMMUNOLOGICAL REVIEWS

Segregation and activation of myosin IIB creates a rear in migrating cells

(2008) Miguel Vicente-Manzanares et al.   JOURNAL OF CELL BIOLOGY

Activation of ERK-FAK Signaling Pathway and Enhancement of Cell Migration Involved in the Early Interaction Between Oral Keratinocytes and Candida albicans

(2008) Jing Shi et al.   MYCOPATHOLOGIA