Locally excitable Cdc42 signals steer cells during chemotaxis

Using light to shape chemical gradients for parallel and automated analysis of chemotaxis

(2015) S. R. Collins et al.   Molecular Systems Biology

Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis

(2014) Ming Tang et al.   Nature Communications

Activated RhoA Is a Positive Feedback Regulator of the Lbc Family of Rho Guanine Nucleotide Exchange Factor Proteins

(2013) Frank Medina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration

(2013) Chuan-Hsiang Huang et al.   NATURE CELL BIOLOGY

Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility

(2013) Amy Friesland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying Network Motifs that Buffer Front-to-Back Signaling in Polarized Neutrophils

(2013) Yanqin Wang et al.   Cell Reports

Designing Synthetic Regulatory Networks Capable of Self-Organizing Cell Polarization

(2012) Angela H. Chau et al.   CELL

Membrane Tension Maintains Cell Polarity by Confining Signals to the Leading Edge during Neutrophil Migration

(2012) Andrew R. Houk et al.   CELL

Biased excitable networks: how cells direct motion in response to gradients

(2011) Pablo A Iglesias et al.   CURRENT OPINION IN CELL BIOLOGY

Symmetry breaking and the establishment of cell polarity in budding yeast

(2011) Jayme M Johnson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Development of an optimized backbone of FRET biosensors for kinases and GTPases

(2011) Naoki Komatsu et al.   MOLECULAR BIOLOGY OF THE CELL

PI3K and Chemotaxis: A Priming Issue?

(2011) P. V. Afonso et al.   Science Signaling

A Comparison of Mathematical Models for Polarization of Single Eukaryotic Cells in Response to Guided Cues

(2011) Alexandra Jilkine et al.   PLoS Computational Biology

Directional Persistence of Cell Migration Coincides with Stability of Asymmetric Intracellular Signaling

(2010) Michael C. Weiger et al.   BIOPHYSICAL JOURNAL

Oscillatory dynamics of the extracellular signal-regulated kinase pathway

(2010) Harish Shankaran et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish

(2010) Sa Kan Yoo et al.   DEVELOPMENTAL CELL

Mechanisms of force generation and force transmission during interstitial leukocyte migration

(2010) Jörg Renkawitz et al.   EMBO REPORTS

Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration

(2009) T. Lammermann et al.   BLOOD

Singularity in Polarization: Rewiring Yeast Cells to Make Two Buds

(2009) Audrey S. Howell et al.   CELL

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

(2009) Kosuke Yusa et al.   NATURE METHODS

On the spontaneous emergence of cell polarity

(2008) Steven J. Altschuler et al.   NATURE

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY

Suspended-drop electroporation for high-throughput delivery of biomolecules into cells

(2008) Emmanuel G Guignet et al.   NATURE METHODS

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY