DNA Polymerase III, but Not Polymerase IV, Must Be Bound to a τ-Containing DnaX Complex to Enable Exchange into Replication Forks

The DNA polymerase III holoenzyme contains γ and is not a trimeric polymerase

(2016) Paul R. Dohrmann et al.   NUCLEIC ACIDS RESEARCH

Exchange betweenEscherichia colipolymerases II and III on a processivity clamp

(2015) James E. Kath et al.   NUCLEIC ACIDS RESEARCH

A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion Synthesis

(2015) Michelle K. Scotland et al.   PLoS Genetics

cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ

(2015) Rafael Fernandez-Leiro et al.   eLife

Replisome-mediated Translesion Synthesis and Leading Strand Template Lesion Skipping Are Competing Bypass Mechanisms

(2014) Carolina B. Gabbai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA polymerase IV mediates efficient and quick recovery of replication forks stalled at N2-dG adducts

(2014) Mio Ikeda et al.   NUCLEIC ACIDS RESEARCH

Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis

(2014) J. E. Kath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A direct proofreader–clamp interaction stabilizes the Pol III replicase in the polymerization mode

(2013) Slobodan Jergic et al.   EMBO JOURNAL

Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork

(2013) Quan Yuan et al.   NUCLEIC ACIDS RESEARCH

Escherichia coli DNA Polymerase IV (Pol IV), but Not Pol II, Dynamically Switches with a Stalled Pol III* Replicase

(2012) J. M. H. Heltzel et al.   JOURNAL OF BACTERIOLOGY

DNA Replicases from a Bacterial Perspective

(2011) Charles S. McHenry   Annual Review of Biochemistry

Structure of the SSB-DNA polymerase III interface and its role in DNA replication

(2011) Aimee H Marceau et al.   EMBO JOURNAL

E. coliDNA replication in the absence of free β clamps

(2011) Nathan A Tanner et al.   EMBO JOURNAL

Polymerase Chaperoning and Multiple ATPase Sites Enable the E. coli DNA Polymerase III Holoenzyme to Rapidly Form Initiation Complexes

(2011) Christopher D. Downey et al.   JOURNAL OF MOLECULAR BIOLOGY

The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis

(2011) Paul R. Dohrmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Single-molecule studies reveal the function of a third polymerase in the replisome

(2011) Roxana E Georgescu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polymerase Exchange During Okazaki Fragment Synthesis Observed in Living Cells

(2011) G. Lia et al.   SCIENCE

Only One ATP-binding DnaX Subunit Is Required for Initiation Complex Formation by theEscherichia coliDNA Polymerase III Holoenzyme

(2010) Anna Wieczorek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chaperoning of a Replicative Polymerase onto a Newly Assembled DNA-Bound Sliding Clamp by the Clamp Loader

(2010) Christopher D. Downey et al.   MOLECULAR CELL

Strand Displacement by DNA Polymerase III Occurs through a τ-ψ-χ Link to Single-stranded DNA-binding Protein Coating the Lagging Strand Template

(2009) Quan Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp

(2009) J. M. H. Heltzel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Dynamic Polymerase Exchange withEscherichia coliDNA Polymerase IV Replacing DNA Polymerase III on the Sliding Clamp

(2008) Asako Furukohri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-molecule studies of fork dynamics in Escherichia coli DNA replication

(2008) Nathan A Tanner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY