Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis

Single-Molecule Approaches Embrace Molecular Cohorts

(2013) Taekjip Ha   CELL

A direct proofreader–clamp interaction stabilizes the Pol III replicase in the polymerization mode

(2013) Slobodan Jergic et al.   EMBO JOURNAL

Architecture of the Pol III–clamp–exonuclease complex reveals key roles of the exonuclease subunit in processive DNA synthesis and repair

(2013) Ana Toste Rêgo et al.   EMBO JOURNAL

Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination

(2013) Richard T Pomerantz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, ε, θ and β reveals a highly flexible arrangement of the proofreading domain

(2013) Kiyoshi Ozawa et al.   NUCLEIC ACIDS RESEARCH

Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation

(2012) Thomas R Beattie et al.   EMBO JOURNAL

Y-family DNA polymerases and their role in tolerance of cellular DNA damage

(2012) Julian E. Sale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Force and ATP hydrolysis dependent regulation of RecA nucleoprotein filament by single-stranded DNA binding protein

(2012) Hongxia Fu et al.   NUCLEIC ACIDS RESEARCH

Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics

(2012) J. J. Foti et al.   SCIENCE

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

(2011) Susan E. Tsutakawa et al.   CELL

Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA

(2011) S. E. Tsutakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli

(2011) S. Gon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange

(2011) Joseph J. Loparo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperoning of a Replicative Polymerase onto a Newly Assembled DNA-Bound Sliding Clamp by the Clamp Loader

(2010) Christopher D. Downey et al.   MOLECULAR CELL

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

(2010) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

(2010) J. S. Graham et al.   NUCLEIC ACIDS RESEARCH

Coordinating DNA polymerase traffic during high and low fidelity synthesis

(2009) Mark D. Sutton   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Distinct β-clamp interactions govern the activities of the Y family PolIV DNA polymerase

(2009) Jérôme Wagner et al.   MOLECULAR MICROBIOLOGY

Contributions of the individual hydrophobic clefts of the Escherichia coli   sliding clamp to clamp loading, DNA replication and clamp recycling

(2009) S. K. Scouten Ponticelli et al.   NUCLEIC ACIDS RESEARCH

A model for DNA polymerase switching involving a single cleft and the rim of the sliding clamp

(2009) J. M. H. Heltzel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase

(2009) C. Indiani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overproduction ofEscherichia coliDNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal

(2008) Kaori Uchida et al.   MOLECULAR MICROBIOLOGY

Single-molecule studies of fork dynamics in Escherichia coli DNA replication

(2008) Nathan A Tanner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of polymerase exchange between Pol  and Pol  by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme

(2008) Z. Zhuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA