Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 25, Pages 13160-13174
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2016-04-29
DOI
10.1074/jbc.m115.691543
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression
- (2014) X.-g. Wu et al. BLOOD
- Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload
- (2014) Sandro Altamura et al. Cell Metabolism
- TGF-β1, but Not Bone Morphogenetic Proteins, Activates Smad1/5 Pathway in Primary Human Macrophages and Induces Expression of Proatherogenic Genes
- (2014) Dinara Nurgazieva et al. JOURNAL OF IMMUNOLOGY
- Systemic Iron Homeostasis
- (2013) Tomas Ganz PHYSIOLOGICAL REVIEWS
- A New Class of Small Molecule Inhibitor of BMP Signaling
- (2013) Caroline E. Sanvitale et al. PLoS One
- TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?
- (2012) David Warburton et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload
- (2012) Maja Vujić Spasić et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation
- (2012) Flavia D’Alessio et al. JOURNAL OF HEPATOLOGY
- Transforming Growth Factor Inhibits Bone Morphogenetic Protein-Induced Transcription through Novel Phosphorylated Smad1/5-Smad3 Complexes
- (2012) E. Gronroos et al. MOLECULAR AND CELLULAR BIOLOGY
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Crosstalk between TGF-β signaling and the microRNA machinery
- (2012) Henriett Butz et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
- (2011) A. U. Steinbicker et al. BLOOD
- Hepcidin regulation by innate immune and infectious stimuli
- (2011) A. E. Armitage et al. BLOOD
- TGF-β in progression of liver disease
- (2011) Steven Dooley et al. CELL AND TISSUE RESEARCH
- Iron Regulation of Hepcidin Despite Attenuated Smad1,5,8 Signaling in Mice Without Transferrin Receptor 2 or Hfe
- (2011) Elena Corradini et al. GASTROENTEROLOGY
- Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice
- (2011) Emilio Ramos et al. HEPATOLOGY
- Spontaneous repopulation of β-catenin null livers with β-catenin-positive hepatocytes after chronic murine liver injury
- (2011) Michael D. Thompson et al. HEPATOLOGY
- The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice
- (2011) Mirco Castoldi et al. JOURNAL OF CLINICAL INVESTIGATION
- Two to Tango: Regulation of Mammalian Iron Metabolism
- (2010) Matthias W. Hentze et al. CELL
- Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis
- (2010) John D. Ryan et al. HEPATOLOGY
- Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes
- (2010) K.W. Finnson et al. OSTEOARTHRITIS AND CARTILAGE
- Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis
- (2009) Elena Corradini et al. GASTROENTEROLOGY
- Transforming Growth Factor β Can Stimulate Smad1 Phosphorylation Independently of Bone Morphogenic Protein Receptors
- (2009) Katharine H. Wrighton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
- (2009) Guillem Casanovas et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
- (2009) Mitsuo Kato et al. NATURE CELL BIOLOGY
- Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
- (2008) Y. Xia et al. BLOOD
- Cancer-Associated Transforming Growth Factor Type II Receptor Gene Mutant Causes Activation of Bone Morphogenic Protein-Smads and Invasive Phenotype
- (2008) S. Bharathy et al. CANCER RESEARCH
- TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch
- (2008) Irwin M Liu et al. EMBO JOURNAL
- ALK1 Opposes ALK5/Smad3 Signaling and Expression of Extracellular Matrix Components in Human Chondrocytes
- (2008) Kenneth W Finnson et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells
- (2008) Maria Vittoria Verga Falzacappa et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Transforming Growth Factor -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth
- (2008) A. C. Daly et al. MOLECULAR AND CELLULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now