Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway

DNA Entry into and Exit out of the Cohesin Ring by an Interlocking Gate Mechanism

(2015) Yasuto Murayama et al.   CELL

Cohesin and human disease: lessons from mouse models

(2015) Vijay Pratap Singh et al.   CURRENT OPINION IN CELL BIOLOGY

Complex elaboration: making sense of meiotic cohesin dynamics

(2015) Susannah Rankin   FEBS Journal

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

(2015) Hyunjoo Cha-Molstad et al.   NATURE CELL BIOLOGY

Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway

(2015) S.-E. Park et al.   SCIENCE

Molecular events and signalling pathways of male germ cell differentiation in mouse

(2015) Moïra Rossitto et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Meiosis: An Overview of Key Differences from Mitosis

(2015) Hiroyuki Ohkura   Cold Spring Harbor Perspectives in Biology

Recombination, Pairing, and Synapsis of Homologs during Meiosis

(2015) Denise Zickler et al.   Cold Spring Harbor Perspectives in Biology

Chromosome Dynamics during Mitosis

(2015) Tatsuya Hirano   Cold Spring Harbor Perspectives in Biology

Germ cell-specific Atg7 knockout results in primary ovarian insufficiency in female mice

(2015) Z-H Song et al.   Cell Death & Disease

The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

(2015) Gamze Çamdere et al.   eLife

Centromeric Heterochromatin: The Primordial Segregation Machine

(2014) Kerry S. Bloom   Annual Review of Genetics

Atg7 is required for acrosome biogenesis during spermatogenesis in mice

(2014) Hongna Wang et al.   CELL RESEARCH

Paradigms of protein degradation by the proteasome

(2014) Tomonao Inobe et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cohesin and Its Regulation: On the Logic of X-Shaped Chromosomes

(2014) Judith H.I. Haarhuis et al.   DEVELOPMENTAL CELL

Chromosome Segregation in Budding Yeast: Sister Chromatid Cohesion and Related Mechanisms

(2014) Adele L. Marston   GENETICS

Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats

(2014) Christopher S. Brower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remodeling of a delivery complex allows ClpS-mediated degradation of N-degron substrates

(2014) Izarys Rivera-Rivera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calpain-generated natural protein fragments as short-lived substrates of the N-end rule pathway

(2014) Konstantin I. Piatkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions

(2014) Daniel J. Gibbs et al.   TRENDS IN CELL BIOLOGY

PINK1 is degraded through the N-end rule pathway

(2013) Koji Yamano et al.   Autophagy

The N-Terminal Methionine of Cellular Proteins as a Degradation Signal

(2013) Heon-Ki Kim et al.   CELL

Spindle Assembly Checkpoint of Oocytes Depends on a Kinetochore Structure Determined by Cohesin in Meiosis I

(2013) Kikuë Tachibana-Konwalski et al.   CURRENT BIOLOGY

Meiosis I: when chromosomes undergo extreme makeover

(2013) Matthew P Miller et al.   CURRENT OPINION IN CELL BIOLOGY

The N-degradome ofEscherichia coli

(2013) Matthew A. Humbard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cohesin codes – interpreting chromatin architecture and the many facets of cohesin function

(2013) Soumya Rudra et al.   JOURNAL OF CELL SCIENCE

Control of Protein Quality and Stoichiometries by N-Terminal Acetylation and the N-End Rule Pathway

(2013) Anna Shemorry et al.   MOLECULAR CELL

Neurodegeneration-Associated Protein Fragments as Short-Lived Substrates of the N-End Rule Pathway

(2013) Christopher S. Brower et al.   MOLECULAR CELL

Characterization of the Interaction between the Cohesin Subunits Rad21 and SA1/2

(2013) Nenggang Zhang et al.   PLoS One

The N-End Rule Pathway

(2012) Takafumi Tasaki et al.   Annual Review of Biochemistry

The Ancient and Evolving Roles of Cohesin in Gene Expression and DNA Repair

(2012) Dale Dorsett et al.   CURRENT BIOLOGY

The DegraBase: A Database of Proteolysis in Healthy and Apoptotic Human Cells

(2012) Emily D. Crawford et al.   MOLECULAR & CELLULAR PROTEOMICS

The Auto-Generated Fragment of the Usp1 Deubiquitylase Is a Physiological Substrate of the N-End Rule Pathway

(2012) Konstantin I. Piatkov et al.   MOLECULAR CELL

Post-replicative repair involves separase-dependent removal of the kleisin subunit of cohesin

(2012) Alexandra McAleenan et al.   NATURE

The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments

(2012) K. I. Piatkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis

(2012) Alexander Varshavsky   PROTEIN SCIENCE

Protein N-terminal acetyltransferases: when the start matters

(2012) Kristian K. Starheim et al.   TRENDS IN BIOCHEMICAL SCIENCES

Sister Chromatid Cohesion

(2012) J.-M. Peters et al.   Cold Spring Harbor Perspectives in Biology

The N-end rule pathway: From recognition by N-recognins, to destruction by AAA+proteases

(2011) D.A. Dougan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Arginyltransferase Is an ATP-Independent Self-Regulating Enzyme that Forms Distinct Functional Complexes In Vivo

(2011) Junling Wang et al.   CHEMISTRY & BIOLOGY

Posttranslational arginylation as a global biological regulator

(2011) Sougata Saha et al.   DEVELOPMENTAL BIOLOGY

The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis

(2011) Yan Yin et al.   DEVELOPMENTAL BIOLOGY

RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis

(2011) Jibak Lee et al.   JOURNAL OF CELL BIOLOGY

Calpain-1 Cleaves Rad21 To Promote Sister Chromatid Separation

(2011) A. K. Panigrahi et al.   MOLECULAR AND CELLULAR BIOLOGY

Meiosis in Mice without a Synaptonemal Complex

(2011) Anna Kouznetsova et al.   PLoS One

The N-end rule pathway and regulation by proteolysis

(2011) Alexander Varshavsky   PROTEIN SCIENCE

The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases

(2010) Cheol-Sang Hwang et al.   NATURE CELL BIOLOGY

Condensin and cohesin complexity: the expanding repertoire of functions

(2010) Andrew J. Wood et al.   NATURE REVIEWS GENETICS

Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases

(2010) Woo Suk Choi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of substrate recognition and specificity in the N-end rule pathway

(2010) Edna Matta-Camacho et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

(2010) C.-S. Hwang et al.   SCIENCE

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I

(2009) N. R. Kudo et al.   JOURNAL OF CELL SCIENCE

Glutamine-Specific N-Terminal Amidase, a Component of the N-End Rule Pathway

(2009) Haiqing Wang et al.   MOLECULAR CELL

Ablation of Arginylation in the Mouse N-End Rule Pathway: Loss of Fat, Higher Metabolic Rate, Damaged Spermatogenesis, and Neurological Perturbations

(2009) Christopher S. Brower et al.   PLoS One

Discovery of Cellular Regulation by Protein Degradation

(2008) Alexander Varshavsky   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway

(2008) Zanxian Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Kleisin Subunit of Cohesin Dictates Damage-Induced Cohesion

(2008) Jill M. Heidinger-Pauli et al.   MOLECULAR CELL

Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway

(2008) C.-S. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA