Förster resonance energy transfer biosensors for fluorescence and time-gated luminescence analysis of rac1 activity

Correction: Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation

(2020) Ying Yan et al.   Oncotarget

Single-Chain Lanthanide Luminescence Biosensors for Cell-Based Imaging and Screening of Protein-Protein Interactions

(2020) Ting Chen et al.   iScience

Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4

(2018) Shirley C. Mills et al.   CELLULAR SIGNALLING

Direct multiplex imaging and optogenetics of Rho GTPases enabled by near-infrared FRET

(2018) Daria M. Shcherbakova et al.   Nature Chemical Biology

Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks

(2018) Eric C. Greenwald et al.   CHEMICAL REVIEWS

Discovery and characterization of small molecule Rac1 inhibitors

(2017) Jamie L. Arnst et al.   Oncotarget

Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells

(2016) Veronika Miskolci et al.   JOURNAL OF IMMUNOLOGY

Mimicking transient activation of protein kinases in living cells

(2016) Jennifer E. Klomp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SrGAP2-Dependent Integration of Membrane Geometry and Slit-Robo-Repulsive Cues Regulates Fibroblast Contact Inhibition of Locomotion

(2015) Rafael Dominik Fritz et al.   DEVELOPMENTAL CELL

Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets

(2015) S. Dütting et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A Trio–Rac1–Pak1 signalling axis drives invadopodia disassembly

(2014) Yasmin Moshfegh et al.   NATURE CELL BIOLOGY

Rho GTPase isoforms in cell motility: Don't fret, we have FRET

(2014) Sara K Donnelly et al.   Cell Adhesion & Migration

Balanced Tiam1-Rac1 and RhoA Drives Proliferation and Invasion of Pancreatic Cancer Cells

(2013) Xingjun Guo et al.   MOLECULAR CANCER RESEARCH

A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space

(2013) R. D. Fritz et al.   Science Signaling

Six-Color Time-Resolved Förster Resonance Energy Transfer for Ultrasensitive Multiplexed Biosensing

(2012) Daniel Geißler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Luminescent Trimethoprim–Polyaminocarboxylate Lanthanide Complex Conjugates for Selective Protein Labeling and Time-Resolved Bioassays

(2011) D. Rajasekhar Reddy et al.   BIOCONJUGATE CHEMISTRY

Development of an optimized backbone of FRET biosensors for kinases and GTPases

(2011) Naoki Komatsu et al.   MOLECULAR BIOLOGY OF THE CELL

Imaging the coordination of multiple signalling activities in living cells

(2011) Christopher M. Welch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Systematic control of protein interaction using a modular ER/K  -helix linker

(2011) S. Sivaramakrishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque

(2010) Suman Dwivedi et al.   Journal of Translational Medicine

Luminescent Terbium Protein Labels for Time-Resolved Microscopy and Screening

(2009) Harsha E. Rajapakse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combining Single-Molecule Optical Trapping and Small-Angle X-Ray Scattering Measurements to Compute the Persistence Length of a Protein ER/K α-Helix

(2009) S. Sivaramakrishnan et al.   BIOPHYSICAL JOURNAL

Virtual Screening Approach for the Identification of New Rac1 Inhibitors

(2009) Nicola Ferri et al.   JOURNAL OF MEDICINAL CHEMISTRY