Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci
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Title
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci
Authors
Keywords
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Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-03-28
DOI
10.1038/s41467-022-29143-5
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Note: Only part of the references are listed.- A cross-platform approach identifies genetic regulators of human metabolism and health
- (2021) Luca A. Lotta et al. NATURE GENETICS
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- (2019) Jason Flannick et al. NATURE
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- (2019) Alana C. Costa et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Exome sequencing of Finnish isolates enhances rare-variant association power
- (2019) Adam E. Locke et al. NATURE
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- (2019) David S. Wishart PHYSIOLOGICAL REVIEWS
- Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study
- (2018) Tanya M Teslovich et al. HUMAN MOLECULAR GENETICS
- Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer’s Disease
- (2018) Xue-Ying He et al. JOURNAL OF ALZHEIMERS DISEASE
- Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
- (2018) Marie Verbanck et al. NATURE GENETICS
- Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
- (2018) Noha A. Yousri et al. Nature Communications
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- (2018) Ling Zhang et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2018) Ayush Giri et al. NATURE GENETICS
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- (2018) Annalisa Buniello et al. NUCLEIC ACIDS RESEARCH
- The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases
- (2017) Markku Laakso et al. JOURNAL OF LIPID RESEARCH
- Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population
- (2017) Yoshiki Yasukochi et al. MOLECULAR GENETICS AND GENOMICS
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- (2017) Tao Long et al. NATURE GENETICS
- HMDB 4.0: the human metabolome database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization
- (2017) Xiaoquan Wen et al. PLoS Genetics
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- (2016) Xiaoquan Wen Annals of Applied Statistics
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- (2016) Christian Benner et al. BIOINFORMATICS
- Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator
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- The genetic architecture of type 2 diabetes
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- (2016) Georg B Ehret et al. NATURE GENETICS
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- (2016) Sayantan Das et al. NATURE GENETICS
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- (2016) Pirjo Käkelä et al. OBESITY SURGERY
- An exome array study of the plasma metabolome
- (2016) Eugene P. Rhee et al. Nature Communications
- Gallstones
- (2016) Frank Lammert et al. Nature Reviews Disease Primers
- Increased frequency of double and triple heterozygous gene variants in children with intrahepatic cholestasis
- (2015) Monique L. Goldschmidt et al. HEPATOLOGY RESEARCH
- Genetics of human metabolism: an update
- (2015) Gabi Kastenmüller et al. HUMAN MOLECULAR GENETICS
- Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
- (2015) J. Bowden et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
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- (2015) Daniela M.T. Malina et al. Journal of Clinical Lipidology
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- (2015) Maria Jimenez-Sanchez et al. Nature Chemical Biology
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- (2015) Robert Vaser et al. Nature Protocols
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- (2014) So-Youn Shin et al. NATURE GENETICS
- MutationTaster2: mutation prediction for the deep-sequencing age
- (2014) Jana Marie Schwarz et al. NATURE METHODS
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