Bacterial quorum sensing and phenotypic heterogeneity: how the collective shapes the individual

Quorum sensing governs a transmissive Legionella subpopulation at the pathogen vacuole periphery

(2021) Bianca Striednig et al.   EMBO REPORTS

The structure of the Legionella response regulator LqsR reveals amino acids critical for phosphorylation and dimerization

(2020) Ramon Hochstrasser et al.   MOLECULAR MICROBIOLOGY

Legionella quorum sensing meets cyclic-di-GMP signaling

(2020) Ramon Hochstrasser et al.   CURRENT OPINION IN MICROBIOLOGY

Quorum sensing controls persistence, resuscitation, and virulence of Legionella subpopulations in biofilms

(2020) Nicolas Personnic et al.   ISME Journal

Impact of bacterial persisters on their host

(2020) Ana L Moldoveanu et al.   CURRENT OPINION IN MICROBIOLOGY

The pleotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence

(2019) Ramon Hochstrasser et al.   ENVIRONMENTAL MICROBIOLOGY

Vibrio variations on a type three theme

(2019) Kelly A Miller et al.   CURRENT OPINION IN MICROBIOLOGY

Phenotypic Heterogeneity in Bacterial Quorum Sensing Systems

(2019) Vera Bettenworth et al.   JOURNAL OF MOLECULAR BIOLOGY

Definitions and guidelines for research on antibiotic persistence

(2019) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Density-dependent resistance protects Legionella pneumophila from its own antimicrobial metabolite, HGA

(2019) Tera C Levin et al.   eLife

Phenotypic Diversification of Microbial Pathogens—Cooperating and Preparing for the Future

(2019) Larissa Schröter et al.   JOURNAL OF MOLECULAR BIOLOGY

Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut

(2019) Erik Bakkeren et al.   NATURE

Quorum sensing modulates the formation of virulent Legionella persisters within infected cells

(2019) Nicolas Personnic et al.   Nature Communications

Legionella quorum sensing and its role in pathogen–host interactions

(2018) Nicolas Personnic et al.   CURRENT OPINION IN MICROBIOLOGY

Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa

(2018) Martina Valentini et al.   CURRENT OPINION IN MICROBIOLOGY

Formation of the Legionella -containing vacuole: phosphoinositide conversion, GTPase modulation and ER dynamics

(2018) Bernhard Steiner et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection

(2018) A. Leoni Swart et al.   Frontiers in Cellular and Infection Microbiology

Progress in and promise of bacterial quorum sensing research

(2017) Marvin Whiteley et al.   NATURE

A Vibrio cholerae autoinducer–receptor pair that controls biofilm formation

(2017) Kai Papenfort et al.   Nature Chemical Biology

Interbacterial predation as a strategy for DNA acquisition in naturally competent bacteria

(2017) Jan-Willem Veening et al.   NATURE REVIEWS MICROBIOLOGY

Legionella and Coxiella effectors: strength in diversity and activity

(2017) Jiazhang Qiu et al.   NATURE REVIEWS MICROBIOLOGY

Rules of Engagement: The Type VI Secretion System in Vibrio cholerae

(2017) Avatar Joshi et al.   TRENDS IN MICROBIOLOGY

Ecological feedback in quorum-sensing microbial populations can induce heterogeneous production of autoinducers

(2017) Matthias Bauer et al.   eLife

Intra-Species and Inter-Kingdom Signaling of Legionella pneumophila

(2017) Ramon Hochstrasser et al.   Frontiers in Microbiology

Immune activation of the host cell induces drug tolerance inMycobacterium tuberculosisboth in vitro and in vivo

(2016) Yancheng Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Exogenous N -acyl-homoserine lactones enhance the expression of flagella of Pseudomonas syringae and activate defence responses in plants

(2016) Feifei Cheng et al.   MOLECULAR PLANT PATHOLOGY

Division of labour in microorganisms: an evolutionary perspective

(2016) Stuart A. West et al.   NATURE REVIEWS MICROBIOLOGY

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Quorum sensing signal–response systems in Gram-negative bacteria

(2016) Kai Papenfort et al.   NATURE REVIEWS MICROBIOLOGY

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

The fitness burden imposed by synthesising quorum sensing signals

(2016) A. Ruparell et al.   Scientific Reports

Phenotypic Heterogeneity, a Phenomenon That May Explain Why Quorum Sensing Does Not Always Result in Truly Homogenous Cell Behavior

(2015) Jessica Grote et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Community Behavior and Spatial Regulation within a Bacterial Microcolony in Deep Tissue Sites Serves to Protect against Host Attack

(2015) Kimberly M. Davis et al.   Cell Host & Microbe

Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms

(2015) Giulia Manina et al.   Cell Host & Microbe

Microbial bet-hedging: the power of being different

(2015) Ard Jan Grimbergen et al.   CURRENT OPINION IN MICROBIOLOGY

The Phosphorylation Flow of the Vibrio harveyi Quorum-Sensing Cascade Determines Levels of Phenotypic Heterogeneity in the Population

(2015) Laure Plener et al.   JOURNAL OF BACTERIOLOGY

The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression ofLegionella pneumophila

(2015) Ursula Schell et al.   MOLECULAR MICROBIOLOGY

A functional perspective on phenotypic heterogeneity in microorganisms

(2015) Martin Ackermann   NATURE REVIEWS MICROBIOLOGY

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms

(2015) Gerardo Cárcamo-Oyarce et al.   Nature Communications

Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway

(2015) Sylvia Simon et al.   PLoS Pathogens

Evidence of Autoinducer-Dependent and -Independent Heterogeneous Gene Expression in Sinorhizobium fredii NGR234

(2014) Jessica Grote et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy

(2014) Beatrice Claudi et al.   CELL

Disparate Impact of Oxidative Host Defenses Determines the Fate of Salmonella during Systemic Infection in Mice

(2014) Neil A. Burton et al.   Cell Host & Microbe

Reversible non-genetic phenotypic heterogeneity in bacterial quorum sensing

(2014) Binod B. Pradhan et al.   MOLECULAR MICROBIOLOGY

Phosphorylation signalling through theLegionellaquorum sensing histidine kinases LqsS and LqsT converges on the response regulator LqsR

(2014) Ursula Schell et al.   MOLECULAR MICROBIOLOGY

Quorum regulatory small RNAs repress type VI secretion inVibrio cholerae

(2014) Yi Shao et al.   MOLECULAR MICROBIOLOGY

Phenotypic bistability in Escherichia coli's central carbon metabolism

(2014) O. Kotte et al.   Molecular Systems Biology

Stochasticity of metabolism and growth at the single-cell level

(2014) Daniel J. Kiviet et al.   NATURE

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

(2014) Markus Arnoldini et al.   PLOS BIOLOGY

Acyl-Homoserine Lactone Quorum Sensing: From Evolution to Application

(2013) Martin Schuster et al.   Annual Review of Microbiology

Analysis of fluorescent reporters indicates heterogeneity in glucose uptake and utilization in clonal bacterial populations

(2013) Nela Nikolic et al.   BMC MICROBIOLOGY

Stabilization of cooperative virulence by the expression of an avirulent phenotype

(2013) Médéric Diard et al.   NATURE

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Single cell analysis of Vibrio harveyi uncovers functional heterogeneity in response to quorum sensing signals

(2012) Claudia Anetzberger et al.   BMC MICROBIOLOGY

TheLegionella pneumophilaorphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit

(2012) Aline Kessler et al.   ENVIRONMENTAL MICROBIOLOGY

Microbial individuality in the natural environment

(2012) M Ackermann   ISME Journal

Autoinducers Act as Biological Timers in Vibrio harveyi

(2012) Claudia Anetzberger et al.   PLoS One

α-Hydroxyketone Synthesis and Sensing by Legionella and Vibrio

(2012) André Tiaden et al.   SENSORS

Correction: A Genome-Wide Analysis of Promoter-Mediated Phenotypic Noise in Escherichia coli

(2012) Olin K. Silander et al.   PLoS Genetics

Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response

(2011) M. K. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cost of Virulence: Retarded Growth of Salmonella Typhimurium Cells Expressing Type III Secretion System 1

(2011) Alexander Sturm et al.   PLoS Pathogens

The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila

(2010) André Tiaden et al.   ENVIRONMENTAL MICROBIOLOGY

Heterogeneous Response to a Quorum-Sensing Signal in the Luminescence of Individual Vibrio fischeri

(2010) Pablo Delfino Pérez et al.   PLoS One

Quorum sensing and a global regulator TsrA control expression of type VI secretion and virulence in Vibrio cholerae

(2010) J. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of intracellular bacterial replication at the single cell level

(2010) Sophie Helaine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

Bacterial gene regulation by α-hydroxyketone signaling

(2010) André Tiaden et al.   TRENDS IN MICROBIOLOGY

Bacterial Quorum-Sensing Network Architectures

(2009) Wai-Leung Ng et al.   Annual Review of Genetics

Inter-kingdom signaling: chemical language between bacteria and host

(2009) Alline R Pacheco et al.   CURRENT OPINION IN MICROBIOLOGY

New developments in microbial interspecies signaling

(2009) Elizabeth Anne Shank et al.   CURRENT OPINION IN MICROBIOLOGY

Heterogeneity in quorum sensing-regulated bioluminescence ofVibrio harveyi

(2009) Claudia Anetzberger et al.   MOLECULAR MICROBIOLOGY

Bistability, Epigenetics, and Bet-Hedging in Bacteria

(2008) Jan-Willem Veening et al.   Annual Review of Microbiology

Synergistic Contribution of the Legionella pneumophila lqs Genes to Pathogen-Host Interactions

(2008) A. Tiaden et al.   JOURNAL OF BACTERIOLOGY

TheLegionellaAutoinducer Synthase LqsA Produces an α-Hydroxyketone Signaling Molecule

(2008) Thomas Spirig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional interplay between theYersinia pseudotuberculosisYpsRI and YtbRI quorum sensing systems modulates swimming motility by controlling expression offlhDCandfliA

(2008) Steve Atkinson et al.   MOLECULAR MICROBIOLOGY