Quorum sensing governs a transmissive Legionella subpopulation at the pathogen vacuole periphery

The structure of the Legionella response regulator LqsR reveals amino acids critical for phosphorylation and dimerization

(2020) Ramon Hochstrasser et al.   MOLECULAR MICROBIOLOGY

Legionella quorum sensing meets cyclic-di-GMP signaling

(2020) Ramon Hochstrasser et al.   CURRENT OPINION IN MICROBIOLOGY

Quorum sensing controls persistence, resuscitation, and virulence of Legionella subpopulations in biofilms

(2020) Nicolas Personnic et al.   ISME Journal

Impact of bacterial persisters on their host

(2020) Ana L Moldoveanu et al.   CURRENT OPINION IN MICROBIOLOGY

Distinct Mycobacterium marinum phosphatases determine pathogen vacuole phosphoinositide pattern, phagosome maturation and escape to the cytosol

(2019) Hendrik Koliwer-Brandl et al.   CELLULAR MICROBIOLOGY

The pleotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence

(2019) Ramon Hochstrasser et al.   ENVIRONMENTAL MICROBIOLOGY

Phenotypic Diversification of Microbial Pathogens—Cooperating and Preparing for the Future

(2019) Larissa Schröter et al.   JOURNAL OF MOLECULAR BIOLOGY

Legionnaires’ Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella

(2019) Sonia Mondino et al.   Annual Review of Pathology-Mechanisms of Disease

Screening Legionella effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication

(2019) Jun-ichi Inaba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quorum sensing modulates the formation of virulent Legionella persisters within infected cells

(2019) Nicolas Personnic et al.   Nature Communications

Legionella quorum sensing and its role in pathogen–host interactions

(2018) Nicolas Personnic et al.   CURRENT OPINION IN MICROBIOLOGY

Formation of the Legionella -containing vacuole: phosphoinositide conversion, GTPase modulation and ER dynamics

(2018) Bernhard Steiner et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection

(2018) A. Leoni Swart et al.   Frontiers in Cellular and Infection Microbiology

Spatially Correlated Gene Expression in Bacterial Groups: The Role of Lineage History, Spatial Gradients, and Cell-Cell Interactions

(2018) Simon van Vliet et al.   Cell Systems

A Surface-Induced Asymmetric Program Promotes Tissue Colonization by Pseudomonas aeruginosa

(2018) Benoît-Joseph Laventie et al.   Cell Host & Microbe

Legionella and Coxiella effectors: strength in diversity and activity

(2017) Jiazhang Qiu et al.   NATURE REVIEWS MICROBIOLOGY

Disulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity

(2017) Christina Lang et al.   Scientific Reports

The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system

(2017) Tobias Sahr et al.   PLoS Genetics

Listeria monocytogenes switches from dissemination to persistence by adopting a vacuolar lifestyle in epithelial cells

(2017) Mounia Kortebi et al.   PLoS Pathogens

The Flagellar Regulon of Legionella—A Review

(2017) Sandra Appelt et al.   Frontiers in Cellular and Infection Microbiology

From Many Hosts, One Accidental Pathogen: The Diverse Protozoan Hosts of Legionella

(2017) David K. Boamah et al.   Frontiers in Cellular and Infection Microbiology

Intra-Species and Inter-Kingdom Signaling of Legionella pneumophila

(2017) Ramon Hochstrasser et al.   Frontiers in Microbiology

Autophagy Evasion and Endoplasmic Reticulum Subversion: The Yin and Yang ofLegionellaIntracellular Infection

(2016) Racquel Kim Sherwood et al.   Annual Review of Microbiology

Inflammasome biology taught by Legionella pneumophila

(2016) Danielle P. A. Mascarenhas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Evaluation and Improvement of Quantification Accuracy in Isobaric Mass Tag-Based Protein Quantification Experiments

(2016) Erik Ahrné et al.   JOURNAL OF PROTEOME RESEARCH

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Subversion of Retrograde Trafficking by Translocated Pathogen Effectors

(2016) Nicolas Personnic et al.   TRENDS IN MICROBIOLOGY

Persister formation in Staphylococcus aureus is associated with ATP depletion

(2016) Brian P. Conlon et al.   Nature Microbiology

Community Behavior and Spatial Regulation within a Bacterial Microcolony in Deep Tissue Sites Serves to Protect against Host Attack

(2015) Kimberly M. Davis et al.   Cell Host & Microbe

Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms

(2015) Giulia Manina et al.   Cell Host & Microbe

Formation of a pathogen vacuole according toLegionella pneumophila: how to kill one bird with many stones

(2015) Ivo Finsel et al.   CELLULAR MICROBIOLOGY

Microbial bet-hedging: the power of being different

(2015) Ard Jan Grimbergen et al.   CURRENT OPINION IN MICROBIOLOGY

Life Stage-specific Proteomes ofLegionella pneumophilaReveal a Highly Differential Abundance of Virulence-associated Dot/Icm effectors

(2015) Philipp Aurass et al.   MOLECULAR & CELLULAR PROTEOMICS

The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signalling and gene expression ofLegionella pneumophila

(2015) Ursula Schell et al.   MOLECULAR MICROBIOLOGY

A functional perspective on phenotypic heterogeneity in microorganisms

(2015) Martin Ackermann   NATURE REVIEWS MICROBIOLOGY

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms

(2015) Gerardo Cárcamo-Oyarce et al.   Nature Communications

Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway

(2015) Sylvia Simon et al.   PLoS Pathogens

Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors

(2015) Sylvia Simon et al.   Frontiers in Immunology

Bacterial Pathogen Manipulation of Host Membrane Trafficking

(2014) Seblewongel Asrat et al.   Annual Review of Cell and Developmental Biology

Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy

(2014) Beatrice Claudi et al.   CELL

A Fluorescent Reporter Reveals On/Off Regulation of the Shigella Type III Secretion Apparatus during Entry and Cell-to-Cell Spread

(2014) François-Xavier Campbell-Valois et al.   Cell Host & Microbe

Disparate Impact of Oxidative Host Defenses Determines the Fate of Salmonella during Systemic Infection in Mice

(2014) Neil A. Burton et al.   Cell Host & Microbe

Phosphorylation signalling through theLegionellaquorum sensing histidine kinases LqsS and LqsT converges on the response regulator LqsR

(2014) Ursula Schell et al.   MOLECULAR MICROBIOLOGY

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during Legionella Infection

(2014) S. Weber et al.   mBio

Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation

(2014) Markus Arnoldini et al.   PLOS BIOLOGY

The natural alternative: protozoa as cellular models forLegionellainfection

(2013) Christine Hoffmann et al.   CELLULAR MICROBIOLOGY

TheLegionella pneumophilaDot/Icm-secreted Effector PlcC/CegC1 Together with PlcA and PlcB Promotes Virulence and Belongs to a Novel Zinc Metallophospholipase C Family Present in Bacteria and Fungi

(2013) Philipp Aurass et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilization of cooperative virulence by the expression of an avirulent phenotype

(2013) Médéric Diard et al.   NATURE

Critical assessment of proteome-wide label-free absolute abundance estimation strategies

(2013) Erik Ahrné et al.   PROTEOMICS

c-di-GMP heterogeneity is generated by the chemotaxis machinery to regulate flagellar motility

(2013) Bridget R Kulasekara et al.   eLife

FliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila

(2012) Tino Schulz et al.   ARCHIVES OF MICROBIOLOGY

TheLegionella pneumophilaorphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit

(2012) Aline Kessler et al.   ENVIRONMENTAL MICROBIOLOGY

Identification of Protective B Cell Antigens of Legionella pneumophila

(2012) S. S. Weber et al.   JOURNAL OF IMMUNOLOGY

Large-Scale Quantitative Assessment of Different In-Solution Protein Digestion Protocols Reveals Superior Cleavage Efficiency of Tandem Lys-C/Trypsin Proteolysis over Trypsin Digestion

(2012) Timo Glatter et al.   JOURNAL OF PROTEOME RESEARCH

The protein SdhA maintains the integrity of the Legionella-containing vacuole

(2012) E. A. Creasey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of NLRC4 by Flagellated Bacteria Triggers Caspase-1-Dependent and -Independent Responses To Restrict Legionella pneumophila Replication in Macrophages and In Vivo

(2011) M. S. F. Pereira et al.   JOURNAL OF IMMUNOLOGY

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

Legionellaspp. outdoors: colonization, communication and persistence

(2011) Hubert Hilbi et al.   Environmental Microbiology Reports

The Nlrc4 Inflammasome Contributes to Restriction of Pulmonary Infection by Flagellated Legionella spp. that Trigger Pyroptosis

(2011) Marcelo S. F. Pereira et al.   Frontiers in Microbiology

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

(2010) H. J. Newton et al.   CLINICAL MICROBIOLOGY REVIEWS

The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila

(2010) André Tiaden et al.   ENVIRONMENTAL MICROBIOLOGY

Pore Formation Triggered by Legionella spp. Is an Nlrc4 Inflammasome-Dependent Host Cell Response That Precedes Pyroptosis

(2010) T. N. Silveira et al.   INFECTION AND IMMUNITY

Distinct roles of ppGpp and DksA inLegionella pneumophiladifferentiation

(2010) Zachary D. Dalebroux et al.   MOLECULAR MICROBIOLOGY

Dynamics of intracellular bacterial replication at the single cell level

(2010) Sophie Helaine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial gene regulation by α-hydroxyketone signaling

(2010) André Tiaden et al.   TRENDS IN MICROBIOLOGY

Molecular mechanism of elongation factor 1A inhibition by aLegionella pneumophilaglycosyltransferase

(2009) Ramon Hurtado-Guerrero et al.   BIOCHEMICAL JOURNAL

Control of Flagellar Gene Regulation in Legionella pneumophila and Its Relation to Growth Phase

(2009) C. Albert-Weissenberger et al.   JOURNAL OF BACTERIOLOGY

 S Controls Multiple Pathways Associated with Intracellular Multiplication of Legionella pneumophila

(2009) G. Hovel-Miner et al.   JOURNAL OF BACTERIOLOGY

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

Large-scale identification ofLegionella pneumophilaDot/Icm substrates that modulate host cell vesicle trafficking pathways

(2008) Matthew Heidtman et al.   CELLULAR MICROBIOLOGY

Synergistic Contribution of the Legionella pneumophila lqs Genes to Pathogen-Host Interactions

(2008) A. Tiaden et al.   JOURNAL OF BACTERIOLOGY

TheLegionellaAutoinducer Synthase LqsA Produces an α-Hydroxyketone Signaling Molecule

(2008) Thomas Spirig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Legionella Eukaryotic-Like Type IV Substrates Interfere with Organelle Trafficking

(2008) Karim Suwwan de Felipe et al.   PLoS Pathogens