A Model of Human Small Airway on a Chip for Studies of Subacute Effects of Inhalation Toxicants

Precision cut lung slices: an ex vivo model for assessing the impact of immunomodulatory therapeutics on lung immune responses

(2021) Guanghui Liu et al.   ARCHIVES OF TOXICOLOGY

Advances in Smoking Related In Vitro Inhalation Toxicology: A Perspective Case of Challenges and Opportunities from Progresses in Lung-on-Chip Technologies

(2021) Ajay Vikram Singh et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Applicability of organ-on-chip systems in toxicology and pharmacology

(2021) Marlon R. Schneider et al.   CRITICAL REVIEWS IN TOXICOLOGY

Multicellular modeling of ciliopathy by combining iPS cells and microfluidic airway-on-a-chip technology

(2021) Naoyuki Sone et al.   Science Translational Medicine

Emerging Technologies for In Vitro Inhalation Toxicology

(2021) Ajay Vikram Singh et al.   Advanced Healthcare Materials

Lung-on-a-chip: the future of respiratory disease models and pharmacological studies

(2020) Jesus Shrestha et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs)

(2020) Amy M. Avila et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models—A Perspective

(2020) Dania Movia et al.   Frontiers in Bioengineering and Biotechnology

Development of an in vitro approach to point-of-contact inhalation toxicity testing of volatile compounds, using organotypic culture and air-liquid interface exposure

(2020) Artik Mistry et al.   TOXICOLOGY IN VITRO

USP9X promotes LPS-induced pulmonary epithelial barrier breakdown and hyperpermeability by activating NF-kBp65 feedback loop

(2019) Yijin Xiang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

In vitro model for predicting acute inhalation toxicity by using a Calu-3 epithelium cytotoxicity assay

(2019) Mi Ho Jeong et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Air-Liquid Interface: Relevant In Vitro Models for Investigating Air Pollutant-Induced Pulmonary Toxicity

(2018) Swapna Upadhyay et al.   TOXICOLOGICAL SCIENCES

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report

(2018) Amy J. Clippinger et al.   TOXICOLOGY IN VITRO

Different concentrations of lipopolysaccharide regulate barrier function through the PI3K/Akt signalling pathway in human pulmonary microvascular endothelial cells

(2018) Xia Zheng et al.   Scientific Reports

Combining MucilAir™ and Vitrocell® Powder Chamber for the In Vitro Evaluation of Nasal Ointments in the Context of Aerosolized Pollen

(2018) Julia Metz et al.   Pharmaceutics

Use of 3D organoids and lung-on-a-chip methods to study lung development, regeneration and disease

(2018) Konstantinos Gkatzis et al.   EUROPEAN RESPIRATORY JOURNAL

TrackMate: An open and extensible platform for single-particle tracking

(2017) Jean-Yves Tinevez et al.   METHODS

A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro

(2017) Kinga Balogh Sivars et al.   TOXICOLOGICAL SCIENCES

Factors of concern in a human 3D cellular airway model exposed to aerosols of nanoparticles

(2017) Ingeborg M. Kooter et al.   TOXICOLOGY IN VITRO

Assessment of biological responses of EpiAirway 3-D cell constructs versus A549 cells for determining toxicity of ambient air pollution

(2016) Jose Zavala et al.   INHALATION TOXICOLOGY

Cells and Culture Systems Used to Model the Small Airway Epithelium

(2016) Rudra Bhowmick et al.   LUNG

A Review of the Comparative Anatomy, Histology, Physiology and Pathology of the Nasal Cavity of Rats, Mice, Dogs and Non-human Primates. Relevance to Inhalation Toxicology and Human Health Risk Assessment

(2015) R. Chamanza et al.   JOURNAL OF COMPARATIVE PATHOLOGY

In vivo–in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems

(2012) Ursula G. Sauer et al.   TOXICOLOGY IN VITRO

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium

(2009) Liqun Zhang et al.   PLOS BIOLOGY