Salvianolic Acid B Suppresses ER Stress-Induced NLRP3 Inflammasome and Pyroptosis via the AMPK/FoxO4 and Syndecan-4/Rac1 Signaling Pathways in Human Endothelial Progenitor Cells

Role of pyroptosis in atherosclerosis and its therapeutic implications

(2021) Bin He et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells

(2021) Stefan Geldon et al.   Frontiers in Cell and Developmental Biology

Inhibition of Rac1 GTPase Decreases Vascular Oxidative Stress, Improves Endothelial Function, and Attenuates Atherosclerosis Development in Mice

(2021) Sebastian Zimmer et al.   Frontiers in Cardiovascular Medicine

Bioactive lipids, inflammation and chronic diseases

(2020) Alessandro Leuti et al.   ADVANCED DRUG DELIVERY REVIEWS

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495

(2020) Katrin Spengler et al.   BIOCHEMICAL JOURNAL

Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1

(2019) Hatem Maamoun et al.   Frontiers in Physiology

New evidence on the role of inflammation in CVD risk

(2019) Alberto J. Lorenzatti et al.   CURRENT OPINION IN CARDIOLOGY

Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation

(2019) Tamami Fujiki et al.   Scientific Reports

ER Stress Activates the NLRP3 Inflammasome: A Novel Mechanism of Atherosclerosis

(2019) Xinnong Chen et al.   Oxidative Medicine and Cellular Longevity

OUP accepted manuscript

(2018)   CARDIOVASCULAR RESEARCH

At the crossway of ER-stress and proinflammatory responses

(2018) Marisa Reverendo et al.   FEBS Journal

ROS signaling and ER stress in cardiovascular disease

(2018) Cristhiaan D. Ochoa et al.   MOLECULAR ASPECTS OF MEDICINE

Globular adiponectin protects hepatocytes from tunicamycin-induced cell death via modulation of the inflammasome and heme oxygenase-1 induction

(2018) Amrita Khakurel et al.   PHARMACOLOGICAL RESEARCH

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

(2018) Yachun Han et al.   Redox Biology

Endoplasmic Reticulum Stress in Metabolic Disorders

(2018) Rose Ghemrawi et al.   Cells

Paeoniflorin attenuates atRAL-induced oxidative stress, mitochondrial dysfunction and endoplasmic reticulum stress in retinal pigment epithelial cells via triggering Ca2+/CaMKII-dependent activation of AMPK

(2018) Xue Zhu et al.   ARCHIVES OF PHARMACAL RESEARCH

Berberine ameliorates lipopolysaccharide-induced acute lung injury via the PERK-mediated Nrf2/HO-1 signaling axis

(2018) Yuan Liang et al.   PHYTOTHERAPY RESEARCH

Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR-223/NLRP3 axis

(2017) Yong Zhang et al.   JOURNAL OF PINEAL RESEARCH

Salvianolic acid B attenuates doxorubicin-induced ER stress by inhibiting TRPC3 and TRPC6 mediated Ca 2+ overload in rat cardiomyocytes

(2017) Rong-chang Chen et al.   TOXICOLOGY LETTERS

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

(2017) Rebecca C. Rabinovitch et al.   Cell Reports

Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

(2017) Miriam Cnop et al.   Molecular Metabolism

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Berberine improves endothelial function by inhibiting endoplasmic reticulum stress in the carotid arteries of spontaneously hypertensive rats

(2015) Limei Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Syndecan-4 Is a Major Syndecan in Primary Human Endothelial Cells In Vitro, Modulated by Inflammatory Stimuli and Involved in Wound Healing

(2015) Tram Thu Vuong et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Metformin Protects Endothelial Function in Diet-Induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5′ Adenosine Monophosphate–Activated Protein Kinase–Peroxisome Proliferator–Activated Receptor δ Pathway

(2014) Wai San Cheang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Salvianolic acid B protects human endothelial progenitor cells against oxidative stress-mediated dysfunction by modulating Akt/mTOR/4EBP1, p38 MAPK/ATF2, and ERK1/2 signaling pathways

(2014) Yubo Tang et al.   BIOCHEMICAL PHARMACOLOGY

NLRP3 Inflammasome as a Novel Player in Myocardial Infarction

(2014) Masafumi Takahashi   International Heart Journal

Die another way – non-apoptotic mechanisms of cell death

(2014) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

Ischemic Preconditioning Provides Neuroprotection by Induction of AMP-Activated Protein Kinase-Dependent Autophagy in a Rat Model of Ischemic Stroke

(2014) Teng Jiang et al.   MOLECULAR NEUROBIOLOGY

Assessment of vascular and endothelial dysfunction in nutritional studies

(2014) S. Ray et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Transcription factor Krüppel-like factor 2 plays a vital role in endothelial colony forming cells differentiation

(2013) Yimeng Song et al.   CARDIOVASCULAR RESEARCH

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Syndecan-4 signaling at a glance

(2013) A. Elfenbein et al.   JOURNAL OF CELL SCIENCE

Thioredoxin-Interacting Protein Mediates ER Stress-Induced β Cell Death through Initiation of the Inflammasome

(2012) Christine M. Oslowski et al.   Cell Metabolism

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Syndecan-4 over-expression preserves cardiac function in a rat model of myocardial infarction

(2012) Jun Xie et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Matrix metalloproteinase-9 induces cardiac fibroblast migration, collagen and cytokine secretion: Inhibition by salvianolic acid B from Salvia miltiorrhiza

(2011) Yanhui Wang et al.   PHYTOMEDICINE

Prostaglandin E2 Promotes Endothelial Differentiation from Bone Marrow-Derived Cells through AMPK Activation

(2011) Zhenjiu Zhu et al.   PLoS One

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Syndecan-4 regulates platelet-derived growth factor-mediated MAP kinase activation by altering intracellular reactive oxygen species

(2008) Jungyean Kim et al.   FEBS LETTERS

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE