The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment strategies
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Title
The intrinsic and microenvironmental features of diffuse midline glioma: Implications for the development of effective immunotherapeutic treatment strategies
Authors
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Journal
NEURO-ONCOLOGY
Volume -, Issue -, Pages -
Publisher
Oxford University Press (OUP)
Online
2022-04-26
DOI
10.1093/neuonc/noac117
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Note: Only part of the references are listed.- GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
- (2022) Robbie G. Majzner et al. NATURE
- Preparing for CAR T cell therapy: patient selection, bridging therapies and lymphodepletion
- (2022) Leila Amini et al. Nature Reviews Clinical Oncology
- Chimeric Antigen Receptor T-cell Therapy for Melanoma
- (2021) Azadehsadat Razavi et al. Expert Review of Clinical Immunology
- A pilot radiogenomic study of DIPG reveals distinct subgroups with unique clinical trajectories and therapeutic targets
- (2021) Xiaoting Zhu et al. Acta Neuropathologica Communications
- Immunotherapeutic Strategies for Neuroblastoma: Present, Past and Future
- (2021) Fabio Morandi et al. Vaccines
- Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma
- (2021) Nikhil C. Munshi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?
- (2021) Brandon Douglas Brown et al. Frontiers in Oncology
- World Cancer Day 2021 - Perspectives in Pediatric and Adult Neuro-Oncology
- (2021) Erik P. Sulman et al. Frontiers in Oncology
- IMMU-11. CLINICAL UPDATES AND CORRELATIVE FINDINGS FROM THE FIRST PATIENT WITH DIPG TREATED WITH INTRACRANIAL CAR T CELLS
- (2021) Nicholas Vitanza et al. NEURO-ONCOLOGY
- Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma
- (2021) Paul Nathan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Breaking barriers: Neurodegenerative repercussions of radiotherapy induced damage on the blood-brain and blood-tumor barrier
- (2021) Barrett D. Allen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dual IGF1R/IR inhibitors in combination with GD2-CAR T-cells display a potent anti-tumor activity in diffuse midline glioma H3K27M-mutant
- (2021) Emmanuel de Billy et al. NEURO-ONCOLOGY
- Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies
- (2021) Izac J. Findlay et al. ONCOGENE
- Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
- (2021) Shaoming Zhu et al. Journal for ImmunoTherapy of Cancer
- ‘Off-the-shelf’ allogeneic CAR T cells: development and challenges
- (2020) S. Depil et al. NATURE REVIEWS DRUG DISCOVERY
- Differential kinase activity of ACVR1 G328V and R206H mutations with implications to possible TβRI cross-talk in diffuse intrinsic pontine glioma
- (2020) Hongnan Cao et al. Scientific Reports
- Combined antitumor effects of anti-EGFR variant III CAR-T cell therapy and PD-1 checkpoint blockade on glioblastoma in mouse model
- (2020) Yujie Song et al. CELLULAR IMMUNOLOGY
- Immune checkpoint inhibition for pediatric patients with recurrent/refractory CNS tumors: a single institution experience
- (2020) Chantel Cacciotti et al. JOURNAL OF NEURO-ONCOLOGY
- Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma
- (2020) Sabine Mueller et al. JOURNAL OF CLINICAL INVESTIGATION
- Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinoma
- (2020) Hao Sun et al. EBioMedicine
- TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML
- (2020) Jayakumar Vadakekolathu et al. Blood Advances
- Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma
- (2020) Michael I. Chastkofsky et al. CLINICAL CANCER RESEARCH
- How to manage patients with corticosteroids in oncology in the era of immunotherapy?
- (2020) Mihaela Aldea et al. EUROPEAN JOURNAL OF CANCER
- Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer
- (2020) Sanja Pajovic et al. Nature Communications
- A Roadmap Toward the Definition of Actionable Tumor-Specific Antigens
- (2020) Robin Minati et al. Frontiers in Immunology
- The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker
- (2020) Denis L. Jardim et al. CANCER CELL
- CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
- (2019) Robbie G. Majzner et al. CLINICAL CANCER RESEARCH
- Treatment Strategies in Diffuse Midline Gliomas With the H3K27M Mutation: The Role of Convection-Enhanced Delivery in Overcoming Anatomic Challenges
- (2019) Benjamin T. Himes et al. Frontiers in Oncology
- Crosslink between Temozolomide and PD-L1 immune-checkpoint inhibition in glioblastoma multiforme
- (2019) Sabrina Heynckes et al. BMC CANCER
- H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo
- (2019) André B. Silveira et al. ACTA NEUROPATHOLOGICA
- Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance
- (2019) Filipe Martins et al. Nature Reviews Clinical Oncology
- Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials
- (2019) Nicholas A. Vitanza et al. Current Treatment Options in Neurology
- Tumor-intrinsic PIK3CA represses tumor immunogenicity in a model of pancreatic cancer
- (2019) Nithya Sivaram et al. JOURNAL OF CLINICAL INVESTIGATION
- Signal Transduction in Diffuse Intrinsic Pontine Glioma
- (2019) Ryan J. Duchatel et al. PROTEOMICS
- The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models
- (2019) Naiara Martínez-Vélez et al. Nature Communications
- B7-H3 as a novel CAR-T therapeutic target for glioblastoma
- (2019) Xin Tang et al. Molecular Therapy-Oncolytics
- Effect of Pembrolizumab After Stereotactic Body Radiotherapy vs Pembrolizumab Alone on Tumor Response in Patients With Advanced Non–Small Cell Lung Cancer
- (2019) Willemijn S. M. E. Theelen et al. JAMA Oncology
- An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
- (2019) Marian L. Burr et al. CANCER CELL
- Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma
- (2019) Chul-Hwan Lee et al. GENES & DEVELOPMENT
- Towards Immunotherapy for Pediatric Brain Tumors
- (2019) Stacie Shiqi Wang et al. TRENDS IN IMMUNOLOGY
- B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres
- (2019) Dean Nehama et al. EBioMedicine
- Analysis of PD‐L1 expression and T cell infiltration in different molecular subgroups of diffuse midline gliomas
- (2019) Prerana Jha et al. NEUROPATHOLOGY
- Mechanisms regulating PD-L1 expression on tumor and immune cells
- (2019) Shuming Chen et al. Journal for ImmunoTherapy of Cancer
- CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma
- (2019) Bryan D. Choi et al. Journal for ImmunoTherapy of Cancer
- IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma
- (2018) Erik Ladomersky et al. CLINICAL CANCER RESEARCH
- Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma
- (2018) Frederick F. Lang et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries
- (2018) Lindsey M. Hoffman et al. JOURNAL OF CLINICAL ONCOLOGY
- Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas
- (2018) Christopher W. Mount et al. NATURE MEDICINE
- Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells
- (2018) Mara Vinci et al. NATURE MEDICINE
- Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
- (2018) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Epithelial-mesenchymal transition (EMT) signature is inversely associated with T-cell infiltration in non-small cell lung cancer (NSCLC)
- (2018) Young Kwang Chae et al. Scientific Reports
- Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma
- (2018) Carter M. Suryadevara et al. OncoImmunology
- Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy
- (2018) Amber J. Giles et al. Journal for ImmunoTherapy of Cancer
- Cytokine release syndrome
- (2018) Alexander Shimabukuro-Vornhagen et al. Journal for ImmunoTherapy of Cancer
- Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma
- (2018) Grant L. Lin et al. Acta Neuropathologica Communications
- DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report
- (2018) Sonia Tejada et al. Frontiers in Oncology
- Immune Response Generated With the Administration of Autologous Dendritic Cells Pulsed With an Allogenic Tumoral Cell-Lines Lysate in Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma
- (2018) Daniel Benitez-Ribas et al. Frontiers in Oncology
- Reirradiation and PD-1 inhibition with nivolumab for the treatment of recurrent diffuse intrinsic pontine glioma: a single-institution experience
- (2018) Cassie Kline et al. JOURNAL OF NEURO-ONCOLOGY
- Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: Implications for development of immunotherapy
- (2018) Nicole A P Lieberman et al. NEURO-ONCOLOGY
- Recent advances in CAR T-cell toxicity: Mechanisms, manifestations and management
- (2018) Jennifer N. Brudno et al. BLOOD REVIEWS
- MRI evaluation of the effects of whole brain radiotherapy on breast cancer brain metastasis
- (2018) William Crowe et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- IMMU-25. PROGRAMMED CELL DEATH-LIGAND 1 (PD-L1) IS NOT EXPRESSED IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) TUMOR CELLS
- (2018) Preet Walia et al. NEURO-ONCOLOGY
- Allogeneic CAR-T Cells: More than Ease of Access?
- (2018) Charlotte Graham et al. Cells
- Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy
- (2017) Zinal S. Chheda et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Preliminary results of immune modulating antibody MDV9300 (pidilizumab) treatment in children with diffuse intrinsic pontine glioma
- (2017) Iris Fried et al. JOURNAL OF NEURO-ONCOLOGY
- Phase 1 Results of ZUMA-1: A Multicenter Study of KTE-C19 Anti-CD19 CAR T Cell Therapy in Refractory Aggressive Lymphoma
- (2017) Frederick L. Locke et al. MOLECULAR THERAPY
- EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
- (2017) Faizaan Mohammad et al. NATURE MEDICINE
- Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study
- (2017) Tabitha Cooney et al. NEURO-ONCOLOGY
- Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
- (2017) Sattva S. Neelapu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Blood–tumor barrier opening changes in brain metastases from pre to one-month post radiation therapy
- (2017) Feifei Teng et al. RADIOTHERAPY AND ONCOLOGY
- Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion
- (2017) Julia V. Cockle et al. Molecular Therapy-Oncolytics
- CTLA-4 and PD-1 Pathways
- (2016) Elizabeth I. Buchbinder et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Coinhibitory Pathways in Immunotherapy for Cancer
- (2016) Susanne H. Baumeister et al. Annual Review of Immunology
- Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
- (2016) Willy Hugo et al. CELL
- Dendritic cell-based immunotherapy
- (2016) Rachel L Sabado et al. CELL RESEARCH
- Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
- (2016) Christine E. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- MYC regulates the antitumor immune response through CD47 and PD-L1
- (2016) S. C. Casey et al. SCIENCE
- Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
- (2015) David Castel et al. ACTA NEUROPATHOLOGICA
- Tumor location, but not H3.3K27M, significantly influences the blood–brain-barrier permeability in a genetic mouse model of pediatric high-grade glioma
- (2015) Ergys Subashi et al. JOURNAL OF NEURO-ONCOLOGY
- Survival prediction model of children with diffuse intrinsic pontine glioma based on clinical and radiological criteria
- (2014) Marc H. Jansen et al. NEURO-ONCOLOGY
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immunology of cancer stem cells in solid tumours. A review
- (2013) Cristina Maccalli et al. EUROPEAN JOURNAL OF CANCER
- The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
- (2013) K.-M. Chan et al. GENES & DEVELOPMENT
- Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas
- (2013) Jing Zeng et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- HLA Class I Alleles Are Associated with Peptide-Binding Repertoires of Different Size, Affinity, and Immunogenicity
- (2013) S. Paul et al. JOURNAL OF IMMUNOLOGY
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- B7-H3, a potential therapeutic target, is expressed in diffuse intrinsic pontine glioma
- (2012) Zhiping Zhou et al. JOURNAL OF NEURO-ONCOLOGY
- Anti-GD2 Antibody Therapy for GD2-Expressing Tumors
- (2010) F. Navid et al. CURRENT CANCER DRUG TARGETS
- Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma
- (2010) J. H. Sampson et al. NEURO-ONCOLOGY
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