Dual IGF1R/IR inhibitors in combination with GD2-CAR T-cells display a potent anti-tumor activity in diffuse midline glioma H3K27M-mutant

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

(2021) David N Louis et al.   NEURO-ONCOLOGY

The Emerging Role of Myeloid-Derived Suppressor Cells in the Glioma Immune Suppressive Microenvironment

(2020) Yajing Mi et al.   Frontiers in Immunology

Adoptive Cell Therapy—Harnessing Antigen-Specific T Cells to Target Solid Tumours

(2020) Elżbieta Chruściel et al.   Cancers

Insulin-like growth factor-1 receptor induces immunosuppression in lung cancer by upregulating B7–H4 expression through the MEK/ERK signaling pathway

(2020) Zhiming Zhao et al.   CANCER LETTERS

CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors

(2019) Robbie G. Majzner et al.   CLINICAL CANCER RESEARCH

Chimeric antigen receptor T cell persistence and memory cell formation

(2019) Alexander D McLellan et al.   IMMUNOLOGY AND CELL BIOLOGY

Diverse immunotherapies can effectively treat syngeneic brainstem tumors in the absence of overt toxicity

(2019) Matthew R. Schuelke et al.   Journal for ImmunoTherapy of Cancer

Clinical trials for diffuse intrinsic pontine glioma: the current state of affairs

(2019) Julian S. Rechberger et al.   CHILDS NERVOUS SYSTEM

Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?

(2019) Fatma E. El-Khouly et al.   JOURNAL OF NEURO-ONCOLOGY

Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening

(2019) Grant L. Lin et al.   Science Translational Medicine

Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma

(2019) Aaron D. Simpson et al.   BRITISH JOURNAL OF CANCER

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

(2018) Alan Mackay et al.   CANCER CELL

Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas

(2018) Christopher W. Mount et al.   NATURE MEDICINE

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells

(2018) Mara Vinci et al.   NATURE MEDICINE

CAR-T cells and combination therapies: What’s next in the immunotherapy revolution?

(2018) Maria C. Ramello et al.   PHARMACOLOGICAL RESEARCH

Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma

(2018) Concetta Quintarelli et al.   OncoImmunology

The Role of the Insulin-Like Growth Factor 1 Pathway in Immune Tumor Microenvironment and Its Clinical Ramifications in Gynecologic Malignancies

(2018) Muna Alemi Yahya et al.   Frontiers in Endocrinology

Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma

(2018) Grant L. Lin et al.   Acta Neuropathologica Communications

CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies

(2018) Hannah M. Knochelmann et al.   Frontiers in Immunology

Survival benefit for patients with diffuse intrinsic pontine glioma (DIPG) undergoing re-irradiation at first progression: A matched-cohort analysis on behalf of the SIOP-E-HGG/DIPG working group

(2017) Geert O. Janssens et al.   EUROPEAN JOURNAL OF CANCER

Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies

(2017) Michaël H. Meel et al.   EXPERIMENTAL CELL RESEARCH

Induction of Regulatory T Cells and Its Regulation with Insulin-like Growth Factor/Insulin-like Growth Factor Binding Protein-4 by Human Mesenchymal Stem Cells

(2017) Ippei Miyagawa et al.   JOURNAL OF IMMUNOLOGY

Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells

(2017) Juliane Gust et al.   Cancer Discovery

IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge

(2017) Olga Spadaro et al.   Cell Reports

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

(2015) Kyle G. Halvorson et al.   PLoS One

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

Genome-Wide Analyses Identify Recurrent Amplifications of Receptor Tyrosine Kinases and Cell-Cycle Regulatory Genes in Diffuse Intrinsic Pontine Glioma

(2011) Barbara S. Paugh et al.   JOURNAL OF CLINICAL ONCOLOGY

Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFR / 

(2011) A. Bielen et al.   MOLECULAR CANCER THERAPEUTICS

IGF-IR in neuroprotection and brain tumors

(2009) Elisa Gualco   Frontiers in Bioscience-Landmark