Differential kinase activity of ACVR1 G328V and R206H mutations with implications to possible TβRI cross-talk in diffuse intrinsic pontine glioma
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Title
Differential kinase activity of ACVR1 G328V and R206H mutations with implications to possible TβRI cross-talk in diffuse intrinsic pontine glioma
Authors
Keywords
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Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-04-09
DOI
10.1038/s41598-020-63061-0
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Note: Only part of the references are listed.- ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis
- (2019) Christine M. Hoeman et al. Nature Communications
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- Bis-Heteroaryl Pyrazoles: Identification of Orally Bioavailable Inhibitors of Activin Receptor-Like Kinase-2 (R206H)
- (2019) Katsuhiko Sekimata et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Transforming Growth Factor-β Signaling in Immunity and Cancer
- (2019) Eduard Batlle et al. IMMUNITY
- Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials
- (2019) Ann Lin et al. Science Translational Medicine
- Effects of FKBP12 and type II BMP receptors on signal transduction by ALK2 activating mutations associated with genetic disorders
- (2018) Aiko Machiya et al. BONE
- ENTPRISE-X: Predicting disease-associated frameshift and nonsense mutations
- (2018) Hongyi Zhou et al. PLoS One
- FINDSITEcomb2.0: A New Approach for Virtual Ligand Screening of Proteins and Virtual Target Screening of Biomolecules
- (2018) Hongyi Zhou et al. Journal of Chemical Information and Modeling
- New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
- (2018) Anushka Dongre et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease
- (2017) Joshua Baugh et al. JOURNAL OF NEURO-ONCOLOGY
- Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
- (2017) Andrea Piunti et al. NATURE MEDICINE
- A knowledge-based approach for predicting gene–disease associations
- (2016) Hongyi Zhou et al. BIOINFORMATICS
- Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads
- (2016) Apirat Chaikuad et al. Cold Spring Harbor Perspectives in Biology
- Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma
- (2016) Hamid Nikbakht et al. Nature Communications
- ENTPRISE: An Algorithm for Predicting Human Disease-Associated Amino Acid Substitutions from Sequence Entropy and Predicted Protein Structures
- (2016) Hongyi Zhou et al. PLoS One
- Cell-of-origin chromatin organization shapes the mutational landscape of cancer
- (2015) Paz Polak et al. NATURE
- Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
- (2015) Catherine S Grasso et al. NATURE MEDICINE
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- Structure–Activity Relationship of 3,5-Diaryl-2-aminopyridine ALK2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants
- (2014) Agustin H. Mohedas et al. JOURNAL OF MEDICINAL CHEMISTRY
- Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
- (2014) Pawel Buczkowicz et al. NATURE GENETICS
- Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
- (2014) Kathryn R Taylor et al. NATURE GENETICS
- Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
- (2014) Rintaro Hashizume et al. NATURE MEDICINE
- Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
- (2014) Kosuke Funato et al. SCIENCE
- Experimental validation of FINDSITEcomb virtual ligand screening results for eight proteins yields novel nanomolar and micromolar binders
- (2014) Bharath Srinivasan et al. Journal of Cheminformatics
- Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor
- (2013) Agustin H. Mohedas et al. ACS Chemical Biology
- A New Class of Small Molecule Inhibitor of BMP Signaling
- (2013) Caroline E. Sanvitale et al. PLoS One
- Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva
- (2012) Apirat Chaikuad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transforming Growth Factor Inhibits Bone Morphogenetic Protein-Induced Transcription through Novel Phosphorylated Smad1/5-Smad3 Complexes
- (2012) E. Gronroos et al. MOLECULAR AND CELLULAR BIOLOGY
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
- (2012) Laurens Kruidenier et al. NATURE
- Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
- (2012) Gang Wu et al. NATURE GENETICS
- In vitro Analyses of the Dysregulated R206H ALK2 Kinase-FKBP12 Interaction Associated with Heterotopic Ossification in FOP
- (2011) Jay C. Groppe et al. CELLS TISSUES ORGANS
- Spatio-temporal transcriptome of the human brain
- (2011) Hyo Jung Kang et al. NATURE
- Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma
- (2011) M. Monje et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors
- (2009) F. Gellibert et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Transforming Growth Factor -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth
- (2008) A. C. Daly et al. MOLECULAR AND CELLULAR BIOLOGY
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