Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors

Toward the Goal of Human Heart Regeneration

(2020) Hesham Sadek et al.   Cell Stem Cell

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

(2020) Li Wang et al.   NATURE CELL BIOLOGY

Long-term functional and structural preservation of precision-cut human myocardium under continuous electromechanical stimulation in vitro

(2019) Carola Fischer et al.   Nature Communications

Regenerating the field of cardiovascular cell therapy

(2019) Kenneth R. Chien et al.   NATURE BIOTECHNOLOGY

YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo

(2019) Tanner O. Monroe et al.   DEVELOPMENTAL CELL

Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract

(2019) Makoto Sahara et al.   DEVELOPMENTAL CELL

Stars in the Night Sky: iPSC-Cardiomyocytes Return the Patient Context to Drug Screening

(2019) Anna Hnatiuk et al.   Cell Stem Cell

MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

(2019) Khatia Gabisonia et al.   NATURE

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias

(2019) Rocco Romagnuolo et al.   Stem Cell Reports

Single-Cell Transcriptomics Reveals Chemotaxis-Mediated Intraorgan Crosstalk During Cardiogenesis

(2019) Haiqing Xiong et al.   CIRCULATION RESEARCH

Clinical Translation of Pluripotent Stem Cell Therapies: Challenges and Considerations

(2019) Manon Desgres et al.   Cell Stem Cell

An acute immune response underlies the benefit of cardiac stem-cell therapy

(2019) Ronald J. Vagnozzi et al.   NATURE

Transplantation of Human Embryonic Stem Cell–Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction

(2018) Philippe Menasché et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Human ISL1 + Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction

(2018) Kylie S. Foo et al.   MOLECULAR THERAPY

Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates

(2018) Yen-Wen Liu et al.   NATURE BIOTECHNOLOGY

Secretome Analysis of Hypoxia-Induced 3T3-L1 Adipocytes Uncovers Novel Proteins Potentially Involved in Obesity

(2018) Anna Elisa Laria et al.   PROTEOMICS

Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq

(2018) Fabienne Lescroart et al.   SCIENCE

A complete workflow for the differentiation and the dissociation of hiPSC-derived cardiospheres

(2018) Benjamin Fischer et al.   Stem Cell Research

TrackMate: An open and extensible platform for single-particle tracking

(2017) Jean-Yves Tinevez et al.   METHODS

The extracellular matrix protein agrin promotes heart regeneration in mice

(2017) Elad Bassat et al.   NATURE

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Redefining the identity of cardiac fibroblasts

(2017) Michelle D. Tallquist et al.   Nature Reviews Cardiology

Cardiac regeneration strategies: Staying young at heart

(2017) Eldad Tzahor et al.   SCIENCE

In Vivo Cellular Reprogramming: The Next Generation

(2016) Deepak Srivastava et al.   CELL

Cardiac Fibrosis

(2016) Joshua G. Travers et al.   CIRCULATION RESEARCH

Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems

(2016) Jason Pellman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Induced pluripotent stem cell technology: a decade of progress

(2016) Yanhong Shi et al.   NATURE REVIEWS DRUG DISCOVERY

Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs

(2016) Andrea Bähr et al.   PLoS One

Dynamics of Cell Generation and Turnover in the Human Heart

(2015) Olaf Bergmann et al.   CELL

Programming and reprogramming a human heart cell

(2015) M. Sahara et al.   EMBO JOURNAL

Epicardial FSTL1 reconstitution regenerates the adult mammalian heart

(2015) Ke Wei et al.   NATURE

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

(2014) James J. H. Chong et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

HCN4 Dynamically Marks the First Heart Field and Conduction System Precursors

(2013) Xingqun Liang et al.   CIRCULATION RESEARCH

A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells

(2013) Daniela Später et al.   NATURE CELL BIOLOGY

Embryonic Heart Progenitors and Cardiogenesis

(2013) T. Brade et al.   Cold Spring Harbor Perspectives in Medicine

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

(2011) J. M. Gonzalez-Rosa et al.   DEVELOPMENT

De novo cardiomyocytes from within the activated adult heart after injury

(2011) Nicola Smart et al.   NATURE

NKX2-5 eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

(2011) David A Elliott et al.   NATURE METHODS

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

(2009) Lei Bu et al.   NATURE

Homing and engraftment of progenitor cells: A prerequisite for cell therapy

(2008) Emmanouil Chavakis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY