Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations

Stopping pandemics before they start: Lessons learned from SARS-CoV-2

(2022) Aled M. Edwards et al.   SCIENCE

Visualizing group II intron dynamics between the first and second steps of splicing

(2020) Jacopo Manigrasso et al.   Nature Communications

The bio-relevant metals of the periodic table of the elements

(2019) Helmut Sigel et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES

Metal Ion-Coordinating Properties in Aqueous Solutions of the Antivirally Active Nucleotide Analogue (S )-9-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine (HPMPA) - Quantification of Complex Isomeric Equilibria

(2019) Claudia A. Blindauer et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Metal-ion binding properties of ( S )-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, Cidofovir). A nucleotide analogue with activity against DNA viruses

(2018) Claudia A. Blindauer et al.   INORGANICA CHIMICA ACTA

Intramolecular π-stacks in mixed-ligand copper(II) complexes formed by heteroaromatic amines and antivirally active acyclic nucleotide analogues carrying a hydroxy-2-(phosphonomethoxy)propyl residue

(2018) Claudia A. Blindauer et al.   JOURNAL OF COORDINATION CHEMISTRY

Metal ion complexes of nucleoside phosphorothioates reflecting the ambivalent properties of lead(ii)

(2018) Astrid Sigel et al.   NEW JOURNAL OF CHEMISTRY

Optimal molecular crowding accelerates group II intron folding and maximizes catalysis

(2018) Bishnu P. Paudel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Catalytic Mechanism of DNA and RNA Polymerases

(2018) Vito Genna et al.   ACS Catalysis

Divalent metal ions control activity and inhibition of protein kinases

(2017) Matthias J. Knape et al.   Metallomics

The structure of a nucleolytic ribozyme that employs a catalytic metal ion

(2017) Yijin Liu et al.   Nature Chemical Biology

A New View into the Regulation of Purine Metabolism: The Purinosome

(2017) Anthony M. Pedley et al.   TRENDS IN BIOCHEMICAL SCIENCES

Approved Antiviral Drugs over the Past 50 Years

(2016) Erik De Clercq et al.   CLINICAL MICROBIOLOGY REVIEWS

(N7)-Platination and its effect on (N1)H-acidification in nucleoside phosphate derivatives

(2016) Astrid Sigel et al.   INORGANICA CHIMICA ACTA

Catalytic Metal Ions and Enzymatic Processing of DNA and RNA

(2015) Giulia Palermo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Solution properties of metal ion complexes formed with the antiviral and cytostatic nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]-2-amino-6-dimethylaminopurine (PME2A6DMAP)

(2014) Raquel B. Gómez-Coca et al.   CANADIAN JOURNAL OF CHEMISTRY

Extent of Intramolecular π-Stacks in Aqueous Solution in Mixed-Ligand Copper(II) Complexes Formed by Heteroaromatic Amines and Several 2-Aminopurine Derivatives of the Antivirally Active Nucleotide Analog 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

(2012) Raquel B. Gómez-Coca et al.   CHEMISTRY & BIODIVERSITY

Unusually High-Affinity Mg2+ Binding at the AU-Rich Sequence within the Antiterminator Hairpin of a Mg2+ Riboswitch

(2012) Maximiliane M. T. Korth et al.   CHEMISTRY & BIODIVERSITY

Price To Be Paid for Two-Metal Catalysis: Magnesium Ions That Accelerate Chemistry Unavoidably Limit Product Release from a Protein Kinase

(2012) Douglas M. Jacobsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding the Acid-Base Properties of Adenosine: The Intrinsic Basicities of N1, N3 and N7

(2011) Larisa E. Kapinos  et al.   CHEMISTRY-A EUROPEAN JOURNAL

MINAS—a database of Metal Ions in Nucleic AcidS

(2011) Joachim Schnabl et al.   NUCLEIC ACIDS RESEARCH

Analysis of Metal Ion Dependence in glmS Ribozyme Self-Cleavage and Coenzyme Binding

(2010) Kevin Klawuhn et al.   CHEMBIOCHEM

Controlling ribozyme activity by metal ions

(2010) Joachim Schnabl et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Metal ion-binding properties of 9-[(2-phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antiviral nucleotide analogue 9-[(2-phosphonomethoxy)ethyl]adenine (PMEA). Steric guiding of metal ion-coordination by the purine-amino group

(2010) Alfonso Fernández-Botello et al.   DALTON TRANSACTIONS

Metal ion-N7 coordination in a ribozyme branch domain by NMR

(2010) Michèle C. Erat et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Riboswitch structure: an internal residue mimicking the purine ligand

(2009) Vanessa Delfosse et al.   NUCLEIC ACIDS RESEARCH

Intramolecular π–π stacking interactions in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and the nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA)

(2008) Alfonso Fernández-Botello et al.   INORGANICA CHIMICA ACTA

Influence of decreased solvent permittivity on the structure and magnesium(II)-binding properties of the catalytic domain 5 of a group II intron ribozyme

(2008) Maya Furler et al.   INORGANICA CHIMICA ACTA

Divalent metal ions tune the self-splicing reaction of the yeast mitochondrial group II intron Sc.ai5γ

(2008) Michèle C. Erat et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Metal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozyme

(2008) J. L. Boots et al.   RNA