Eriodictyol and Homoeriodictyol Improve Memory Impairment in Aβ25–35-Induced Mice by Inhibiting the NLRP3 Inflammasome

Amentoflavone Ameliorates Memory Deficits and Abnormal Autophagy in Aβ25−35-Induced Mice by mTOR Signaling

(2021) Bing Cao et al.   NEUROCHEMICAL RESEARCH

Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity

(2021) Yuan Gao et al.   Cell Communication and Signaling

Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer’s Disease

(2021) Wen Zhou et al.   Frontiers in Aging Neuroscience

Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity

(2021) Nan Qin et al.   Frontiers of Medicine

NLRP3 Inflammasome: A Starring Role in Amyloid-β- and Tau-Driven Pathological Events in Alzheimer’s Disease

(2021) Mariana Van Zeller et al.   JOURNAL OF ALZHEIMERS DISEASE

Expression of Immune Related Genes and Possible Regulatory Mechanisms in Alzheimer’s Disease

(2021) Yanjun Lu et al.   Frontiers in Immunology

Camellia oil inhibits oxidative stress and inflammatory response to ameliorate LPS-induced acute kidney injury via downregulation of TLR4-mediated activation of the NF-κB/AP-1/IRF3 and NLRP3 pathways

(2020) Mengnan Zeng et al.   Journal of Functional Foods

TLR4 Cross-Talk With NLRP3 Inflammasome and Complement Signaling Pathways in Alzheimer's Disease

(2020) Junling Yang et al.   Frontiers in Immunology

Alzheimer’s disease: new concepts on the role of autoimmunity and of NLRP3 inflammasome in the pathogenesis of the disease

(2020) Cinzia Severini et al.   Current Neuropharmacology

Ameliorating Activity of Ishige okamurae on the Amyloid Beta–Induced Cognitive Deficits and Neurotoxicity through Regulating ERK, p38 MAPK, and JNK Signaling in Alzheimer's Disease–Like Mice Model

(2020) Oh Yun Kwon et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Raw and salt-processed Achyranthes bidentata attenuate LPS-induced acute kidney injury by inhibiting ROS and apoptosis via an estrogen-like pathway

(2020) Shengchao Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

The immune system on the TRAIL of Alzheimer’s disease

(2020) Chiara Burgaletto et al.   Journal of Neuroinflammation

Blood-Brain Barrier Permeability of Asiaticoside, Madecassoside and Asiatic Acid in Porcine Brain Endothelial Cell Model

(2020) Nur Aziah Hanapi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanisms of NLRP3 Inflammasome Activation: Its Role in the Treatment of Alzheimer’s Disease

(2020) Yidan Zhang et al.   NEUROCHEMICAL RESEARCH

The involvement of NLRP3 inflammasome in the treatment of Alzheimer’s disease

(2020) Ya-Shuo Feng et al.   AGEING RESEARCH REVIEWS

Non-steroidal Anti-inflammatory Drugs as Candidates for the Prevention or Treatment of Alzheimer’s Disease: Do they Still Have a Role?

(2020) Alberto Villarejo-Galende et al.   Current Alzheimer Research

The Complexity of Microglial Interactions With Innate and Adaptive Immune Cells in Alzheimer’s Disease

(2020) Season K. Wyatt-Johnson et al.   Frontiers in Aging Neuroscience

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

The fruit of Crataegus pinnatifida ameliorates memory deficits in β-amyloid protein-induced Alzheimer's disease mouse model

(2019) Jihye Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol

(2019) Solomon Habtemariam   Oxidative Medicine and Cellular Longevity

Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis

(2018) Chun-Yan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer’s disease

(2018) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulatory Roles of Flavonoids on Inflammasome Activation during Inflammatory Responses

(2018) Young-Su Yi   MOLECULAR NUTRITION & FOOD RESEARCH

Eriodictyol Attenuates LPS-Induced Neuroinflammation, Amyloidogenesis, and Cognitive Impairments via the Inhibition of NF-κB in Male C57BL/6J Mice and BV2 Microglial Cells

(2018) Pandi He et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibitors of NF-κB and P2X7/NLRP3/Caspase 1 pathway in microglia: Novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimer’s disease

(2018) Baban S. Thawkar et al.   JOURNAL OF NEUROIMMUNOLOGY

Functional alterations of myeloid cells during the course of Alzheimer’s disease

(2018) Aaron D. Thome et al.   Molecular Neurodegeneration

Microglia in Alzheimer's Disease: Risk Factors and Inflammation

(2018) Atsuko Katsumoto et al.   Frontiers in Neurology

Factors underlying cognitive decline in old age and Alzheimer’s disease: the role of the hippocampus

(2017) Wafa Jaroudi et al.   REVIEWS IN THE NEUROSCIENCES

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

(2017) Lindsay M. Lueptow   Jove-Journal of Visualized Experiments

The road to restoring neural circuits for the treatment of Alzheimer's disease

(2016) Rebecca G. Canter et al.   NATURE

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Eriodictyol Attenuates β-Amyloid 25–35 Peptide-Induced Oxidative Cell Death in Primary Cultured Neurons by Activation of Nrf2

(2015) Xu Jing et al.   NEUROCHEMICAL RESEARCH

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eriodictyol, a plant flavonoid, attenuates LPS-induced acute lung injury through its antioxidative and anti-inflammatory activity

(2015) GUANG-FA ZHU et al.   Experimental and Therapeutic Medicine

Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases

(2015) Paola Bossù et al.   Frontiers in Immunology

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

(2015) Amy M Pooler et al.   Acta Neuropathologica Communications

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

β-amyloid Peptides and Amyloid Plaques in Alzheimer’s Disease

(2014) Gunnar K. Gouras et al.   Neurotherapeutics

Oxidative stress in Alzheimer’s disease

(2014) Zhichun Chen et al.   Neuroscience Bulletin

Oxidative stress and mitochondrial dysfunction in Alzheimer's disease

(2013) Xinglong Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1  Release

(2013) F. Laudisi et al.   JOURNAL OF IMMUNOLOGY

Discovery of potential cyclooxygenase inhibitors using in silico docking studies

(2012) Arumugam Madeswaran et al.   Bangladesh Journal of Pharmacology

Mycobacterium tuberculosis Infection of Dendritic Cells Leads to Partially Caspase-1/11-Independent IL-1β and IL-18 Secretion but Not to Pyroptosis

(2012) Hana Abdalla et al.   PLoS One

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18

(2010) S. Jha et al.   JOURNAL OF NEUROSCIENCE

Inflammation, microglia, and alzheimer's disease

(2009) Brent Cameron et al.   NEUROBIOLOGY OF DISEASE

Unknown

(2008) G Irvine et al.   MOLECULAR MEDICINE