Chronic stress disrupts the homeostasis and progeny progression of oligodendroglial lineage cells, associating immune oligodendrocytes with prefrontal cortex hypomyelination

Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders

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Depression Mediated By Inflammatory Responses To Chronic Stress

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Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons

(2020) Corina Nagy et al.   NATURE NEUROSCIENCE

ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

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Neuroimmune mechanisms and sex/gender-dependent effects in the pathophysiology of mental disorders

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Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes

(2019) Marlijn van der Poel et al.   Nature Communications

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

The behavioral sequelae of social defeat require microglia and are driven by oxidative stress in mice

(2019) Michael L. Lehmann et al.   JOURNAL OF NEUROSCIENCE

Comprehensive Integration of Single-Cell Data

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Augmentation effect of ketamine by guanosine in the novelty-suppressed feeding test is dependent on mTOR signaling pathway

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White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group

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Region-specific myelin differences define behavioral consequences of chronic social defeat stress in mice

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Oligodendrocyte precursor cells present antigen and are cytotoxic targets in inflammatory demyelination

(2019) Leslie Kirby et al.   Nature Communications

Immune cell modulation of oligodendrocyte lineage cells

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation

(2018) Xiang Nie et al.   NEURON

Non-canonical Wnt signaling regulates neural stem cell quiescence during homeostasis and after demyelination

(2018) Manideep Chavali et al.   Nature Communications

Vesicular glutamate release from central axons contributes to myelin damage

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Neuroinflammation: Microglia and T Cells Get Ready to Tango

(2018) Sjoerd T. T. Schetters et al.   Frontiers in Immunology

Suppressing interferon gamma stimulates microglial responses and repair of microbleeds in the diabetic brain

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Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

(2018) Ana Mendanha Falcão et al.   NATURE MEDICINE

Oligodendrocytes — active accomplices in MS pathogenesis?

(2018) Charlotte Ridler   Nature Reviews Neurology

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(2017) Xiaojie Qiu et al.   NATURE METHODS

Chronic social defeat reduces myelination in the mouse medial prefrontal cortex

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Effects of the mode of re-socialization after juvenile social isolation on medial prefrontal cortex myelination and function

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Chronic stress regulates NG2 + cell maturation and myelination in the prefrontal cortex through induction of death receptor 6

(2016) Youjun Yang et al.   EXPERIMENTAL NEUROLOGY

Harnessing the integrated stress response for the treatment of multiple sclerosis

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NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

The recovery trajectory of adolescent social defeat stress-induced behavioral, 1H-MRS metabolites and myelin changes in Balb/c mice

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Age-Dependent Netrin-1 Signaling Regulates NG2+ Glial Cell Spatial Homeostasis in Normal Adult Gray Matter

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Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

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A New Outlook on Mental Illnesses: Glial Involvement Beyond the Glue

(2015) Maha Elsayed et al.   Frontiers in Cellular Neuroscience

Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic

(2015) Sharon W. Way et al.   Nature Communications

Oligodendrocyte Precursor Cells Synthesize Neuromodulatory Factors

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Defining Critical White Matter Pathways Mediating Successful Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression

(2014) Patricio Riva-Posse et al.   BIOLOGICAL PSYCHIATRY

NG2 cells (polydendrocytes): Listeners to the neural network with diverse properties

(2014) Robert A. Hill et al.   GLIA

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Lead-induced effects on learning/memory and fear/anxiety are correlated with disturbances in specific cholinesterase isoform activity and redox imbalance in adult brain

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

The brain reward circuitry in mood disorders

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Fiji: an open-source platform for biological-image analysis

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Impaired adult myelination in the prefrontal cortex of socially isolated mice

(2012) Jia Liu et al.   NATURE NEUROSCIENCE

The Role of Medial Prefrontal Cortex in Memory and Decision Making

(2012) David R. Euston et al.   NEURON

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

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Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress

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Dystroglycan promotes filopodial formation and process branching in differentiating oligodendroglia

(2011) Christopher Eyermann et al.   JOURNAL OF NEUROCHEMISTRY

A standardized protocol for repeated social defeat stress in mice

(2011) Sam A Golden et al.   Nature Protocols

Abnormal Left and Right Amygdala-Orbitofrontal Cortical Functional Connectivity to Emotional Faces: State Versus Trait Vulnerability Markers of Depression in Bipolar Disorder

(2010) Amelia Versace et al.   BIOLOGICAL PSYCHIATRY

Evaluation of 5-ethynyl-2′-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system

(2010) Chenbo Zeng et al.   BRAIN RESEARCH

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Stress signalling pathways that impair prefrontal cortex structure and function

(2009) Amy F. T. Arnsten   NATURE REVIEWS NEUROSCIENCE

Chronic Stress Causes Frontostriatal Reorganization and Affects Decision-Making

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Maturation-dependent sensitivity of oligodendrocyte lineage cells to apoptosis: implications for normal development and disease

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PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

(2008) Leanne E Rivers et al.   NATURE NEUROSCIENCE

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

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