Incidence and risk factors of drug‐induced liver injury

HERBAL AND DIETARY SUPPLEMENTS-INDUCED LIVER INJURY IN LATIN AMERICA: EXPERIENCE FROM THE LATINDILI NETWORK

(2021) Fernando Bessone et al.   Clinical Gastroenterology and Hepatology

Comprehensive analysis and insights gained from long-term experience of the Spanish DILI registry

(2021) Camilla Stephens et al.   JOURNAL OF HEPATOLOGY

Ashwagandha‐induced liver injury: A case series from Iceland and the US Drug‐Induced Liver Injury Network

(2020) Helgi K. Björnsson et al.   LIVER INTERNATIONAL

Cytochrome P450 2E1 and its roles in disease

(2020) F. Peter Guengerich   CHEMICO-BIOLOGICAL INTERACTIONS

HLA-B*14:01 and HLA-B*35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury

(2020) Yi-Ju Li et al.   HEPATOLOGY

Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

(2020) Lorenzo Galluzzi et al.   Nature Reviews Clinical Oncology

Drug induced liver injury: an update

(2020) Miren Garcia-Cortes et al.   ARCHIVES OF TOXICOLOGY

A Phase 1 study of gefitinib combined with durvalumab in EGFR TKI-naive patients with EGFR mutation-positive locally advanced/metastatic non-small-cell lung cancer

(2020) Benjamin C. Creelan et al.   BRITISH JOURNAL OF CANCER

HLA‐B*35:01 and Green Tea Induced Liver Injury

(2020) Jay H. Hoofnagle et al.   HEPATOLOGY

Drug-induced liver injury in older people

(2020) M Isabel Lucena et al.   Lancet Gastroenterology & Hepatology

Genetic risk factors in the development of idiosyncratic drug-induced liver injury

(2020) Camilla Stephens et al.   Expert Opinion on Drug Metabolism & Toxicology

A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury

(2019) Elizabeth T. Cirulli et al.   GASTROENTEROLOGY

EASL Clinical Practice Guidelines: Drug-induced liver injury

(2019) Raúl Andrade et al.   JOURNAL OF HEPATOLOGY

Incidence and Etiology of Drug-Induced Liver Injury in Mainland China

(2019) Tao Shen et al.   GASTROENTEROLOGY

Drug-Induced Acute-on-Chronic Liver Failure in Asian Patients

(2019) Harshad Devarbhavi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Epidemiology of drug-induced liver injury in a University Hospital from Colombia: Updated RUCAM being used for prospective causality assessment

(2019) Alejandra Cano-Paniagua et al.   Annals of Hepatology

Shared genetic risk factors across carbamazepine‐induced hypersensitivity reactions

(2019) Paola Nicoletti et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Development and Validation of Model Consisting of Comorbidity Burden to Calculate Risk of Death Within 6 months for Patients With Suspected Drug-Induced Liver Injury

(2019) Marwan Ghabril et al.   GASTROENTEROLOGY

Drug-Induced Liver Injury — Types and Phenotypes

(2019) Jay H. Hoofnagle et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drug-induced liver injury

(2019) Raul J. Andrade et al.   Nature Reviews Disease Primers

Non‐alcoholic fatty liver disease is a potential risk factor for liver injury caused by immune checkpoint inhibitor

(2019) Koji Sawada et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Acute Liver Failure Secondary to Drug-Induced Liver Injury

(2019) Maneerat Chayanupatkul et al.   Clinics in Liver Disease

Drug-Induced Liver Injury in the Setting of Chronic Liver Disease

(2019) Nicholas A. Hoppmann et al.   Clinics in Liver Disease

WHO global progress report on tuberculosis elimination

(2019) Emilia Harding   Lancet Respiratory Medicine

High Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries

(2018) Miguel E. Zoubek et al.   Clinical Gastroenterology and Hepatology

Herbal and Dietary Supplement-Induced Liver Injuries in the Spanish DILI Registry

(2018) Inmaculada Medina-Caliz et al.   Clinical Gastroenterology and Hepatology

Phase 1/2 Study of the Safety and Tolerability of Nivolumab Plus Crizotinib for the First-Line Treatment of Anaplastic Lymphoma Kinase Translocation — Positive Advanced Non–Small Cell Lung Cancer (CheckMate 370)

(2018) David R. Spigel et al.   Journal of Thoracic Oncology

Hepatotoxicity of immune checkpoint inhibitors: An evolving picture of risk associated with a vital class of immunotherapy agents

(2018) Daniel L. Suzman et al.   LIVER INTERNATIONAL

Advances in studies of tyrosine kinase inhibitors and their acquired resistance

(2018) Qinlian Jiao et al.   Molecular Cancer

The role of HLA-A*33:01 in patients with cholestatic hepatitis attributed to terbinafine

(2018) Robert John Fontana et al.   JOURNAL OF HEPATOLOGY

Liver transplantation and the use of KAVA: Case report

(2018) Matheus William Becker et al.   PHYTOMEDICINE

Patients With Chronic Liver Disease Suggestive of Nonalcoholic Fatty Liver Disease May Be at Higher Risk for Drug-Induced Liver Injury

(2018) Craig Lammert et al.   Clinical Gastroenterology and Hepatology

Analysis of 307 cases with drug-induced liver injury between 2010 and 2018 in Japan

(2018) Mitsuhiko Aiso et al.   HEPATOLOGY RESEARCH

Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗ 35:02 as a risk factor

(2017) Thomas Jacob Urban et al.   JOURNAL OF HEPATOLOGY

Drug-induced acute liver failure in children and adults: Results of a single-centre study of 128 patients

(2017) Harshad Devarbhavi et al.   LIVER INTERNATIONAL

Acute liver failure induced by idiosyncratic reaction to drugs: Challenges in diagnosis and therapy

(2017) Shannan R. Tujios et al.   LIVER INTERNATIONAL

Clinical Features and Outcomes of Complementary and Alternative Medicine Induced Acute Liver Failure and Injury

(2016) Luke Hillman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A Model to predict severity of drug-induced liver injury in humans

(2016) Minjun Chen et al.   HEPATOLOGY

NAT2 slow acetylator associated with anti-tuberculosis drug-induced liver injury in Thai patients

(2016) S. Wattanapokayakit et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination

(2016) Celine Boutros et al.   Nature Reviews Clinical Oncology

HLA-DRB1*16

(2016) Paola Nicoletti et al.   Pharmacogenetics and Genomics

Correlation of CpG Island Methylation of the Cytochrome P450 2E1/2D6 Genes with Liver Injury Induced by Anti-Tuberculosis Drugs: A Nested Case-Control Study

(2016) Jinling Zhang et al.   International Journal of Environmental Research and Public Health

HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer

(2015) C.-F. Xu et al.   CLINICAL CANCER RESEARCH

Population-Representative Incidence of Drug-Induced Acute Liver Failure Based on an Analysis of an Integrated Health Care System

(2015) David S. Goldberg et al.   GASTROENTEROLOGY

Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study

(2015) Naga Chalasani et al.   GASTROENTEROLOGY

Acute liver failure following atorvastatin dose escalation: Is there a threshold dose for idiosyncratic hepatotoxicity?

(2015) Miguel F. Carrascosa et al.   JOURNAL OF HEPATOLOGY

Drug-induced liver injury: Interactions between drug properties and host factors

(2015) Minjun Chen et al.   JOURNAL OF HEPATOLOGY

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

(2015) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

(2014) Naga P Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mechanism of hepatotoxicity due to black cohosh (Cimicifuga racemosa): Histological, immunohistochemical and electron microscopy analysis of two liver biopsies with clinical correlation

(2014) Elena T. Enbom et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump

(2014) Michael D. Aleo et al.   HEPATOLOGY

Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network

(2014) Victor J. Navarro et al.   HEPATOLOGY

Prospective Validation ofHLA-DRB1*07:01Allele Carriage As a Predictive Risk Factor for Lapatinib-Induced Liver Injury

(2014) Daniel J. Schaid et al.   JOURNAL OF CLINICAL ONCOLOGY

A detection algorithm for drug-induced liver injury in medical information databases using the Japanese diagnostic scale and its comparison with the Council for International Organizations of Medical Sciences/the Roussel Uclaf Causality Assessment Method

(2014) Tadaaki Hanatani et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Epidemiology and Risk Factors for Idiosyncratic Drug-Induced Liver Injury

(2014) Einar Björnsson   SEMINARS IN LIVER DISEASE

Genetic Basis of Drug-Induced Liver Injury: Present and Future

(2014) Thomas Urban et al.   SEMINARS IN LIVER DISEASE

The Liver Toxicity Knowledge Base: A Systems Approach to a Complex End Point

(2013) M Chen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland

(2013) Einar S. Björnsson et al.   GASTROENTEROLOGY

Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma WithEGFRMutations

(2013) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

Drug-induced liver injury in obesity

(2013) Bernard Fromenty   JOURNAL OF HEPATOLOGY

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity

(2013) Camilla Stephens et al.   PLoS One

A Prospective Nationwide Study of Drug-Induced Liver Injury in Korea

(2012) Ki Tae Suk et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Risk of tyrosine kinase inhibitors-induced hepatotoxicity in cancer patients: A meta-analysis

(2012) Yi Ling Teo et al.   CANCER TREATMENT REVIEWS

Drug-Induced Liver Disease

(2012) Timothy J. Davern   Clinics in Liver Disease

High lipophilicity and high daily dose of oral medications are associated with significant risk for drug-induced liver injury

(2012) Minjun Chen et al.   HEPATOLOGY

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer

(2011) Colin F. Spraggs et al.   JOURNAL OF CLINICAL ONCOLOGY

Characteristics of Idiosyncratic Drug-induced Liver Injury in Children

(2011) Jean P. Molleston et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

(2011) G Yimer et al.   PHARMACOGENOMICS JOURNAL

Single-Center Experience With Drug-Induced Liver Injury From India: Causes, Outcome, Prognosis and Predictors of Mortality

(2010) Harshad Devarbhavi et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development

(2010) Richard A. Thompson et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method

(2010) Don C. Rockey et al.   HEPATOLOGY

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

The Characteristics and Clinical Outcome of Drug-induced Liver Injury

(2010) Ramazan Idilman et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Herbal medicine hepatotoxicity: A new step with development of specific biomarkers

(2010) Dominique Larrey et al.   JOURNAL OF HEPATOLOGY

Propylthiouracil use associated with severe hepatotoxicity in children

(2010) Linda Koch   Nature Reviews Endocrinology

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

(2010) Makoto Maemondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development

(2010) Ryan E. Morgan et al.   TOXICOLOGICAL SCIENCES

Drug-Induced Liver Injury Network (DILIN) Prospective Study

(2009) Robert J. Fontana et al.   DRUG SAFETY

Phenotypic characterization of idiosyncratic drug-induced liver injury: The influence of age and sex

(2009) M. Isabel Lucena et al.   HEPATOLOGY

Drug-induced liver injury in Japan: An analysis of 1676 cases between 1997 and 2006

(2009) Hajime Takikawa et al.   HEPATOLOGY RESEARCH

Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

(2009) Jedd D Wolchok et al.   LANCET ONCOLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Physiochemical drug properties associated with in vivo toxicological outcomes

(2008) Jason D. Hughes et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Prognostic Utility of the Bilirubin Lactate and Etiology Score

(2008) William Bernal et al.   Clinical Gastroenterology and Hepatology

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

(2008) Naga Chalasani et al.   GASTROENTEROLOGY

Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: Search for signals

(2008) Craig Lammert et al.   HEPATOLOGY