Respiratory Influenza Virus Infection Causes Dynamic Tuft Cell and Innate Lymphoid Cell Changes in the Small Intestine

A proximal-to-distal survey of healthy adult human small intestine and colon epithelium by single-cell transcriptomics

(2022) Joseph Burclaff et al.   Cellular and Molecular Gastroenterology and Hepatology

Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions

(2021) Tessa J. Nash et al.   Communications Biology

Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity

(2020) Christoph S. N. Klose et al.   CELL RESEARCH

Interaction between microbiota and immunity in health and disease

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Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity

(2020) John W. McGinty et al.   IMMUNITY

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Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation

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The relationship between the gut microbiome and host gene expression: a review

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Tuning tuft cells: new ligands and effector functions reveal tissue-specific function

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Development of solitary chemosensory cells in the distal lung after severe influenza injury

(2019) Chetan K Rane et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Intestinal dysbacteriosis-induced IL-25 promotes development of HCC via alternative activation of macrophages in tumor microenvironment

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Innate Lymphoid Cells in Mucosal Immunity

(2019) Santosh K. Panda et al.   Frontiers in Immunology

Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance

(2019) Jessica K. Fiege et al.   PLoS Pathogens

Mouse-adapted H9N2 avian influenza virus causes systemic infection in mice

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A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

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Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

(2018) Marija S. Nadjsombati et al.   IMMUNITY

Annual estimates of the burden of seasonal influenza in the United States: A tool for strengthening influenza surveillance and preparedness

(2018) Melissa A. Rolfes et al.   Influenza and Other Respiratory Viruses

Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps

(2018) Michael A. Kohanski et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tasting type 2 inflammation in the airways

(2018) Robert J. Snelgrove et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interpreting heterogeneity in intestinal tuft cell structure and function

(2018) Amrita Banerjee et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

(2018) Weiwei Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solitary chemosensory cells producing interleukin-25 and group-2 innate lymphoid cells are enriched in chronic rhinosinusitis with nasal polyps

(2018) Neil N. Patel et al.   International Forum of Allergy & Rhinology

Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression

(2018) Neha Vashist et al.   Frontiers in Immunology

Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

(2018) Soner Yildiz et al.   Microbiome

Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

(2018) Corey N. Miller et al.   NATURE

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

(2018) Lindsey W. Plasschaert et al.   NATURE

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

(2018) Daniel T. Montoro et al.   NATURE

Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo

(2018) Louisa E. Sjaastad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Drivers of Pathology in Zoonotic Avian Influenza: The Interplay Between Host and Pathogen

(2018) William S. J. Horman et al.   Frontiers in Immunology

A single-cell survey of the small intestinal epithelium

(2017) Adam L. Haber et al.   NATURE

Guards at the gate: physiological and pathological roles of tissue-resident innate lymphoid cells in the lung

(2017) Hang Cheng et al.   Protein & Cell

Skn-1a/Pou2f3 functions as a master regulator to generate Trpm5-expressing chemosensory cells in mice

(2017) Junpei Yamashita et al.   PLoS One

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

(2016) Meital Gury-BenAri et al.   CELL

Intestinal tuft cells: epithelial sentinels linking luminal cues to the immune system

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Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Maintenance of gut homeostasis by the mucosal immune system

(2016) Ryu OKUMURA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Human Influenza Virus Infections

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The Role of Viral, Host, and Secondary Bacterial Factors in Influenza Pathogenesis

(2015) John C. Kash et al.   AMERICAN JOURNAL OF PATHOLOGY

Small intestinal injury in mice infected with respiratory influenza A virus: evidence for virus induced gastroenteritis

(2015) Shouping Zhang et al.   BIOTECHNOLOGY LETTERS

Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection

(2015) Michael C. Abt et al.   Cell Host & Microbe

Investigating Influenza A Virus Infection: Tools To Track Infection and Limit Tropism: TABLE 1

(2015) Jessica K. Fiege et al.   JOURNAL OF VIROLOGY

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses

(2015) Kazuyo Moro et al.   NATURE IMMUNOLOGY

Innate lymphoid cells: A new paradigm in immunology

(2015) G. Eberl et al.   SCIENCE

Interferons and viruses: an evolutionary arms race of molecular interactions

(2015) Hans-Heinrich Hoffmann et al.   TRENDS IN IMMUNOLOGY

Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know?

(2015) Laetitia Minodier et al.   Virology Journal

Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium

(2014) Tatsuya Yamaguchi et al.   BMC NEUROSCIENCE

MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

(2014) Christopher J. Oliphant et al.   IMMUNITY

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

(2014) Jian Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mammalian gut immunity

(2014) Matam Vijay-Kumar et al.   Biomedical Journal

Pou2f3/Skn-1a Is Necessary for the Generation or Differentiation of Solitary Chemosensory Cells in the Anterior Nasal Cavity

(2013) Makoto OHMOTO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

Interleukin-22 Reduces Lung Inflammation during Influenza A Virus Infection and Protects against Secondary Bacterial Infection

(2013) S. Ivanov et al.   JOURNAL OF VIROLOGY

The mammalian gene function resource: the international knockout mouse consortium

(2012) Allan Bradley et al.   MAMMALIAN GENOME

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

(2012) Christian Quast et al.   NUCLEIC ACIDS RESEARCH

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

(2011) Shinichiro Sawa et al.   NATURE IMMUNOLOGY

Influenza virus infection among pediatric patients reporting diarrhea and influenza-like illness

(2010) Charisma Dilantika et al.   BMC INFECTIOUS DISEASES

Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection

(2010) Kelvin K. W. To et al.   CLINICAL INFECTIOUS DISEASES

DCAMKL-1 Expression Identifies Tuft Cells Rather Than Stem Cells in the Adult Mouse Intestinal Epithelium

(2009) François Gerbe et al.   GASTROENTEROLOGY

Triple-Reassortant Swine Influenza A (H1) in Humans in the United States, 2005–2009

(2009) Vivek Shinde et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

Avian Influenza H6 Viruses Productively Infect and Cause Illness in Mice and Ferrets

(2008) L. Gillim-Ross et al.   JOURNAL OF VIROLOGY