EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells
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Title
EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells
Authors
Keywords
Apoptosis, PMAIP1, MCL1, USP9X, DDIT3, ER stress, EHMT2, BIX-01294
Journal
Cancer Cell International
Volume 15, Issue 1, Pages 4
Publisher
Springer Nature
Online
2015-02-03
DOI
10.1186/s12935-014-0149-x
References
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Note: Only part of the references are listed.- Immunohistochemistry for Histone H3 Lysine 9 Methyltransferase and Demethylase Proteins in Human Melanomas
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- (2014) B. Lehnertz et al. GENES & DEVELOPMENT
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- (2014) J Yan et al. Cell Death & Disease
- Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells
- (2013) Ziyan Lu et al. ANTI-CANCER DRUGS
- BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production
- (2013) Yunha Kim et al. Autophagy
- Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells
- (2013) Tianliang Li et al. Autophagy
- Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim
- (2013) Tom Verfaillie et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation
- (2013) Jane Ding et al. Cell Metabolism
- α-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation
- (2013) Sung-Jin Kim et al. Immune Network
- The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition
- (2012) Chander Peddaboina et al. BMC CANCER
- PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response
- (2012) Miri Jwa et al. NATURE CELL BIOLOGY
- Autophagy Induced by Calcium Phosphate Precipitates Involves Endoplasmic Reticulum Membranes in Autophagosome Biogenesis
- (2012) Xi Chen et al. PLoS One
- Molecular Pharmacological Studies on the Protection Mechanism against Endoplasmic Reticulum Stress-induced Neurodegenerative Disease
- (2012) Masayuki Kaneko YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
- Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis
- (2011) Christopher M. Scull et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Noxa controls Mule-dependent Mcl-1 ubiquitination through the regulation of the Mcl-1/USP9X interaction
- (2011) Patricia Gomez-Bougie et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Salermide up-regulates death receptor 5 expression through the ATF4-ATF3-CHOP axis and leads to apoptosis in human cancer cells
- (2011) Guangbo Liu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The adaptor protein CRK is a pro-apoptotic transducer of endoplasmic reticulum stress
- (2011) Kathryn Austgen et al. NATURE CELL BIOLOGY
- A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
- (2011) Masoud Vedadi et al. Nature Chemical Biology
- 5-Aza-2′-deoxycytidine stress response and apoptosis in prostate cancer
- (2011) Aditi Patra et al. Clinical Epigenetics
- Epigenetic cancer therapy: Proof of concept and remaining challenges
- (2010) Cora Mund et al. BIOESSAYS
- H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM
- (2010) M.-W. Chen et al. CANCER RESEARCH
- G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53
- (2010) Jing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
- (2009) Martin Schwickart et al. NATURE
- BH3-only proteins in apoptosis and beyond: an overview
- (2009) E Lomonosova et al. ONCOGENE
- Coupling of Endoplasmic Reticulum Stress to CDDO-Me-Induced Up-regulation of Death Receptor 5 via a CHOP-Dependent Mechanism Involving JNK Activation
- (2008) W. Zou et al. CANCER RESEARCH
- Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds
- (2008) Yan Shi et al. Cell Stem Cell
- Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
- (2008) Inki Kim et al. NATURE REVIEWS DRUG DISCOVERY
- Downregulation of Histone H3 Lysine 9 Methyltransferase G9a Induces Centrosome Disruption and Chromosome Instability in Cancer Cells
- (2008) Yutaka Kondo et al. PLoS One
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