Structure-Guided Designing Pre-Organization in Bivalent Aptamers

Aptamer Blocking Strategy Inhibits SARS‐CoV‐2 Virus Infection

(2021) Miao Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, optimization and analysis of large DNA and RNA nanostructures through interactive visualization, editing and molecular simulation

(2020) Erik Poppleton et al.   NUCLEIC ACIDS RESEARCH

Strategies to bioengineer aptamer-driven nanovehicles as exceptional molecular tools for targeted therapeutics: A review

(2020) Ramesh Thevendran et al.   JOURNAL OF CONTROLLED RELEASE

Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities

(2020) Ali Aghebat Rafat et al.   Nature Chemistry

Genetically Encoded, Functional Single‐Strand RNA Origami: Anticoagulant

(2019) Abhichart Krissanaprasit et al.   ADVANCED MATERIALS

DNA Nanoscaffold‐Assisted Selection of Femtomolar Bivalent Aptamers for Human α‐Thrombin with Potent Anticoagulant Activity

(2019) Yu Zhou et al.   CHEMBIOCHEM

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

(2019) Paul S. Kwon et al.   Nature Chemistry

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Tailored protein encapsulation into a DNA host using geometrically organized supramolecular interactions

(2017) Andreas Sprengel et al.   Nature Communications

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

A Case Study of the Likes and Dislikes of DNA and RNA in Self-Assembly

(2015) Hua Zuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A family of DNA aptamers with varied duplex region length that forms complexes with thrombin and prothrombin

(2015) V.A. Spiridonova et al.   FEBS LETTERS

Protein Activity Regulation: Inhibition by Closed-Loop Aptamer-Based Structures and Restoration by Near-IR Stimulation

(2015) Jie Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding

(2015) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

Recent Advances in Engineering Polyvalent Biological Interactions

(2014) Chad T. Varner et al.   BIOMACROMOLECULES

Duplex–quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer

(2013) Irene Russo Krauss et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons

(2013) Tandis Vazin et al.   BIOMATERIALS

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible Regulation of Protein Binding Affinity by a DNA Machine

(2012) Chao Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selection is more intelligent than design: improving the affinity of a bivalent ligand through directed evolution

(2012) Kareem M. Ahmad et al.   NUCLEIC ACIDS RESEARCH

The persistence length and length per base of single-stranded DNA obtained from fluorescence correlation spectroscopy measurements using mean field theory

(2012) Qingjia Chi et al.   PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS

Aptamers and the next generation of diagnostic reagents

(2012) Varatharasa Thiviyanathan et al.   Proteomics Clinical Applications

Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer

(2011) Ronak Savla et al.   JOURNAL OF CONTROLLED RELEASE

DNA Nanostructures as Models for Evaluating the Role of Enthalpy and Entropy in Polyvalent Binding

(2011) Jeanette Nangreave et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures

(2011) Abhijit Rangnekar et al.   Nanomedicine-Nanotechnology Biology and Medicine

Self-assembling RNA square

(2011) S. M. Dibrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multitasking with ubiquitin through multivalent interactions

(2010) Fen Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Self-assembled DNA nanostructures for distance-dependent multivalent ligand–protein binding

(2008) Sherri Rinker et al.   Nature Nanotechnology

Molecular assembly for high-performance bivalent nucleic acid inhibitor

(2008) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improvement of Aptamer Affinity by Dimerization

(2008) Hijiri Hasegawa et al.   SENSORS