Genetically Encoded, Functional Single‐Strand RNA Origami: Anticoagulant

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Development of a genetically encodable FRET system using fluorescent RNA aptamers

(2018) Mette D. E. Jepsen et al.   Nature Communications

Programmed Switching of Single Polymer Conformation on DNA Origami

(2016) Abhichart Krissanaprasit et al.   ACS Nano

Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures

(2016) Abhijit Rangnekar et al.   MOLECULES

Routing of individual polymers in designed patterns

(2015) Jakob Bach Knudsen et al.   Nature Nanotechnology

Transcription yield of fully 2′-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants

(2015) Adam J. Meyer et al.   NUCLEIC ACIDS RESEARCH

New oral anticoagulants: their advantages and disadvantages compared with vitamin K antagonists in the prevention and treatment of patients with thromboembolic events

(2015) Agon Mekaj et al.   Therapeutics and Clinical Risk Management

Venous thrombosis

(2015) Alisa S. Wolberg et al.   Nature Reviews Disease Primers

A single-stranded architecture for cotranscriptional folding of RNA nanostructures

(2014) C. Geary et al.   SCIENCE

Sensitization of Transforming Growth Factor-β Signaling by Multiple Peptides Patterned on DNA Nanostructures

(2013) Ronnie O. Pedersen et al.   BIOMACROMOLECULES

A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity

(2012) K. M. BOMPIANI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Organization of Inorganic Nanomaterials via Programmable DNA Self-Assembly and Peptide Molecular Recognition

(2011) Joshua D. Carter et al.   ACS Nano

Increased anticoagulant activity of thrombin-binding DNA aptamers by nanoscale organization on DNA nanostructures

(2011) Abhijit Rangnekar et al.   Nanomedicine-Nanotechnology Biology and Medicine

National Estimates of Emergency Department Visits for Hemorrhage-Related Adverse Events From Clopidogrel Plus Aspirin and From Warfarin

(2010) Nadine Shehab et al.   ARCHIVES OF INTERNAL MEDICINE

NUPACK: Analysis and design of nucleic acid systems

(2010) Joseph N. Zadeh et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Weave Tile Architecture Construction Strategy for DNA Nanotechnology

(2010) Majken N. Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Phase 1b Randomized Study of Antidote-Controlled Modulation of Factor IXa Activity in Patients With Stable Coronary Artery Disease

(2008) Mark Y. Chan et al.   CIRCULATION

SELEX with modified nucleotides

(2008) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A randomized, repeat-dose, pharmacodynamic and safety study of an antidote-controlled factor IXa inhibitor

(2008) M. Y. CHAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Crystal structure of an RNA aptamer bound to thrombin

(2008) S. B. Long et al.   RNA