Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State

Nutraceutical Properties of Mediterranean Diet and Cognitive Decline: Possible Underlying Mechanisms

(2017) Vincenza Frisardi et al.   JOURNAL OF ALZHEIMERS DISEASE

Modulation of Hydrogen Peroxide and Acrolein-Induced Oxidative Stress, Mitochondrial Dysfunctions and Redox Regulated Pathways by the Bacopa Monniera Extract: Potential Implication in Alzheimer's Disease

(2017) Manjeet Singh et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular Regulations Induced by Acrolein in Neuroblastoma SK-N-SH Cells: Relevance to Alzheimer's Disease

(2017) Dang Thanh Nam et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of By-Products of Lipid Oxidation in Alzheimer's Disease Brain: A Focus on Acrolein

(2017) Manjeet Singh et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative stress in Alzheimer disease and mild cognitive impairment: evidence from human data provided by redox proteomics

(2015) Aaron M. Swomley et al.   ARCHIVES OF TOXICOLOGY

Evaluation of dementia by acrolein, amyloid-β and creatinine

(2015) Kazuei Igarashi et al.   CLINICA CHIMICA ACTA

Oxidative stress and lipid peroxidation are upstream of amyloid pathology

(2015) Muriel Arimon et al.   NEUROBIOLOGY OF DISEASE

Distinction between mild cognitive impairment and Alzheimer's disease by CSF amyloid β40 and β42, and protein-conjugated acrolein

(2014) Mutsumi Mizoi et al.   CLINICA CHIMICA ACTA

The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios

(2014) Heike J. Wobst et al.   FEBS LETTERS

Protection of the Developing Brain with Anthocyanins Against Ethanol-Induced Oxidative Stress and Neurodegeneration

(2014) Shahid Ali Shah et al.   MOLECULAR NEUROBIOLOGY

Guarana (Paullinia cupanaMart.) Prevents β-Amyloid Aggregation, Generation of Advanced Glycation-end Products (AGEs), and Acrolein-Induced Cytotoxicity on Human Neuronal-Like Cells

(2014) Leonardo da Silva Bittencourt et al.   PHYTOTHERAPY RESEARCH

Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications

(2014) Jun Wang et al.   Frontiers in Aging Neuroscience

The worldwide economic impact of dementia 2010

(2013) Anders Wimo et al.   Alzheimers & Dementia

Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies

(2013) Aaron M. Swomley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases

(2013) Myung Hee Park et al.   Biomolecules & Therapeutics

Reductive stress in young healthy individuals at risk of Alzheimer disease

(2013) Mari-Carmen Badía et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of Nutrition and Diet in Alzheimer Disease: A Systematic Review

(2013) Rusha Shah   Journal of the American Medical Directors Association

Curcumin protects neuronal-like cells against acrolein by restoring Akt and redox signaling pathways

(2013) Sihem Doggui et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells

(2013) Yingjuan Huang et al.   NEUROSCIENCE LETTERS

Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB

(2013) Xin Zhou et al.   NUTRITION

Kenyan purple tea anthocyanins ability to cross the blood brain barrier and reinforce brain antioxidant capacity in mice

(2013) Khalid Rashid et al.   NUTRITIONAL NEUROSCIENCE

Gadd153 and NF-κB Crosstalk Regulates 27-Hydroxycholesterol-Induced Increase in BACE1 and β-Amyloid Production in Human Neuroblastoma SH-SY5Y Cells

(2013) Gurdeep Marwarha et al.   PLoS One

Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo

(2013) Ying-Juan Huang et al.   TOXICOLOGY LETTERS

Green tea: A promising natural product in oral health

(2012) Baruch Narotzki et al.   ARCHIVES OF ORAL BIOLOGY

Augmented glutathione synthesis decreases acrolein toxicity

(2012) Hideyuki Tomitori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite

(2012) Madoka Yoshida et al.   CLINICA CHIMICA ACTA

Effects of Polyphenols on Brain Ageing and Alzheimer’s Disease: Focus on Mitochondria

(2012) Sebastian Schaffer et al.   MOLECULAR NEUROBIOLOGY

Protective effect of cyanidin 3-O-glucoside on beta-amyloid peptide-induced cognitive impairment in rats

(2012) Lina Qin et al.   NEUROSCIENCE LETTERS

Protective effect of cyanidin-3-O-β-D-glucopyranoside fraction from mulberry fruit pigment against oxidative damage in streptozotocin-induced diabetic rat bladder

(2012) U-Syn Ha et al.   NEUROUROLOGY AND URODYNAMICS

A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes

(2011) Ejaz Ahmad et al.   BIOCHIMIE

Challenges associated with curcumin therapy in Alzheimer disease

(2011) Abdenour Belkacemi et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP–PKA-dependent signaling pathway

(2011) Wei Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Time sequence of oxidative stress in the brain from transgenic mouse models of Alzheimer's disease related to the amyloid-β cascade

(2011) Abdenour Belkacemi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cyanidin-3-glucoside ameliorates ethanol neurotoxicity in the developing brain

(2011) Zunji Ke et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Protein-conjugated acrolein as a biochemical marker of brain infarction

(2011) Kazuei Igarashi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Acrolein scavengers: Reactivity, mechanism and impact on health

(2011) Qin Zhu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Oleuropein and derivatives from olives as Tau aggregation inhibitors

(2011) Anthony Daccache et al.   NEUROCHEMISTRY INTERNATIONAL

Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease

(2011) Cai Wang et al.   NEUROSCIENCE LETTERS

Neuroprotective effects of anthocyanins on apoptosis induced by mitochondrial oxidative stress

(2011) Natalie Kelsey et al.   NUTRITIONAL NEUROSCIENCE

The impact of fruit flavonoids on memory and cognition

(2010) Jeremy P. E. Spencer   BRITISH JOURNAL OF NUTRITION

Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease

(2010) M.A. Bradley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Xenobiotic Metabolism and Berry Flavonoid Transport across the Blood−Brain Barrier†

(2010) Paul E. Milbury et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Blueberry Supplementation Improves Memory in Older Adults†

(2010) Robert Krikorian et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex

(2010) Mubeen A. Ansari et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Resveratrol Protects Human Retinal Pigment Epithelial Cells from Acrolein-Induced Damage

(2010) Shwu-Jiuan Sheu et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

The pattern of human tau phosphorylation is the result of priming and feedback events in primary hippocampal neurons

(2010) J. Bertrand et al.   NEUROSCIENCE

Anthocyanins: Natural Colorants with Health-Promoting Properties

(2010) Jian He et al.   Annual Review of Food Science and Technology

Potential Role of Acrolein in Neurodegeneration and in Alzheimers Disease

(2010) Dang Thanh Nam et al.   Current Molecular Pharmacology

Delphinidin Ameliorates Beta-Amyloid-Induced Neurotoxicity by Inhibiting Calcium Influx and Tau Hyperphosphorylation

(2009) Hyo-Shin KIM et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment

(2009) Robert Krikorian et al.   BRITISH JOURNAL OF NUTRITION

Natural Polyphenols as Direct Trapping Agents of Lipid Peroxidation-Derived Acrolein and 4-Hydroxy-trans-2-nonenal

(2009) Qin Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Molecular pathways of aging and hypertension

(2009) Giovanni G Camici et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Different inhibitory response of cyanidin and methylene blue for filament formation of tau microtubule-binding domain

(2008) Masaki Hattori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protective effect of Pycnogenol in human neuroblastoma SH-SY5Y cells following acrolein-induced cytotoxicity

(2008) Mubeen A. Ansari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of Anthocyanins in the Liver, Eye, and Brain of Blueberry-Fed Pigs

(2008) Wilhelmina Kalt et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Challenges for Research on Polyphenols from Foods in Alzheimer’s Disease: Bioavailability, Metabolism, and Cellular and Molecular Mechanisms

(2008) Manjeet Singh et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY