AβPP/PS1 Transgenic Mice Show Sex Differences in the Cerebellum Associated with Aging

PPARγ agonist pioglitazone improves cerebellar dysfunction at pre-Aβ deposition stage in APPswe/PS1dE9 Alzheimer's disease model mice

(2016) Junya Toba et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study

(2015) Sophie Sérrière et al.   NEUROBIOLOGY OF AGING

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Astroglial cell subtypes in the cerebella of normal adults, elderly adults, and patients with Alzheimer's disease: A histological and immunohistochemical comparison

(2014) María-Isabel Álvarez et al.   GLIA

Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis

(2014) Diego Sepulveda-Falla et al.   JOURNAL OF CLINICAL INVESTIGATION

Impairments of long-term depression induction and motor coordination precede Aβ accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice

(2014) Yuki Kuwabara et al.   JOURNAL OF NEUROCHEMISTRY

Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences

(2014) Michelle Mielke et al.   Clinical Epidemiology

Synaptic Changes in the Dentate Gyrus of APP/PS1 Transgenic Mice Revealed by Electron Microscopy

(2013) Lidia Alonso-Nanclares et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Characterization of the APP/PS1 mouse model of Alzheimer's disease in senescence accelerated background

(2013) Kenghoe Lok et al.   NEUROSCIENCE LETTERS

Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease

(2013) Sharon C Yates et al.   Acta Neuropathologica Communications

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

(2012) Lucía Chávez-Gutiérrez et al.   EMBO JOURNAL

Suppression of survival signalling pathways by the phosphatase PHLPP

(2012) Audrey K. O’Neill et al.   FEBS Journal

Sex Steroid Levels and AD-Like Pathology in 3xTgAD Mice

(2012) C. R. Overk et al.   JOURNAL OF NEUROENDOCRINOLOGY

Sex and Gender Differences in Alzheimer's Disease: Recommendations for Future Research

(2012) Christine L. Carter et al.   JOURNAL OF WOMENS HEALTH

Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Excitability and Synaptic Alterations in the Cerebellum of APP/PS1 Mice

(2012) Eriola Hoxha et al.   PLoS One

GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease

(2012) Willem Kamphuis et al.   PLoS One

Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease

(2011) Ester Aso et al.   BRAIN PATHOLOGY

Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease

(2011) Huaqi Xiong et al.   Neuroscience Bulletin

Rapamycin promotes β-amyloid production via ADAM-10 inhibition

(2010) Sheqing Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease

(2010) Diego Sepulveda-Falla et al.   BRAIN PATHOLOGY

β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration

(2010) Mirsada Čaušević et al.   NEUROSCIENCE LETTERS

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Variations in the neuropathology of familial Alzheimer’s disease

(2009) Claire Shepherd et al.   ACTA NEUROPATHOLOGICA

Cerebellum and Nonmotor Function

(2009) Peter L. Strick et al.   Annual Review of Neuroscience

Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death

(2009) Lisa Chakrabarti et al.   Molecular Brain