When cyclin‐dependent kinases meet viral infections, including SARS‐CoV‐2

Regulation of HBV Replication by Cyclin Docking Motifs in Core Protein

(2021) Haitao Liu et al.   JOURNAL OF VIROLOGY

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells

(2021) Charlotte Martinat et al.   Nature Communications

Development of a PROTAC-Based Targeting Strategy Provides a Mechanistically Unique Mode of Anti-Cytomegalovirus Activity

(2021) Friedrich Hahn et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular microRNA-127-3p suppresses oncogenic herpesvirus-induced transformation and tumorigenesis via down-regulation of SKP2

(2021) Soo Mi Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs

(2020) Sangeun Jeon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Global Phosphorylation Landscape of SARS-CoV-2 Infection

(2020) Mehdi Bouhaddou et al.   CELL

S-like phase CDKs stabilize the Epstein-Barr virus BDLF4 protein to temporally control late gene transcription

(2019) Yoshitaka Sato et al.   JOURNAL OF VIROLOGY

Multisite phosphorylation code of CDK

(2019) Mihkel Örd et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus

(2018) Junji Xing et al.   JOURNAL OF IMMUNOLOGY

Cyclin-dependent kinase activity is required for type I interferon production

(2018) Oya Cingöz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression

(2018) Tonya Kueck et al.   eLife

Breaking Bad: How Viruses Subvert the Cell Cycle

(2018) Ying Fan et al.   Frontiers in Cellular and Infection Microbiology

TRIM29 promotes progression of thyroid carcinoma via activating P13K/AKT signaling pathway

(2017) Jinkai Xu et al.   ONCOLOGY REPORTS

TRIM29 promotes DNA virus infections by inhibiting innate immune response

(2017) Junji Xing et al.   Nature Communications

Cyclin-dependent kinases as therapeutic targets for HIV-1 infection

(2016) Andrew P. Rice   EXPERT OPINION ON THERAPEUTIC TARGETS

Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract

(2016) Junji Xing et al.   NATURE IMMUNOLOGY

HCV-Mediated Apoptosis of Hepatocytes in Culture and Viral Pathogenesis

(2016) Erica Silberstein et al.   PLoS One

Cyclin D3-dependent control of the dNTP pool and HIV-1 replication in human macrophages

(2015) Alba Ruiz et al.   CELL CYCLE

CDK11 in TREX/THOC Regulates HIV mRNA 3′ End Processing

(2015) Vladimir Pak et al.   Cell Host & Microbe

Cyclin L2 Is a Critical HIV Dependency Factor in Macrophages that Controls SAMHD1 Abundance

(2015) George Boateng Kyei et al.   Cell Host & Microbe

Herpes Simplex Virus 1 Upregulates p35, Alters CDK-5 Localization, and Stimulates CDK-5 Kinase Activity during Acute Infection in Neurons

(2015) Heba H. Mostafa et al.   JOURNAL OF VIROLOGY

Palbociclib, a selective inhibitor of cyclin-dependent kinase4/6, blocks HIV-1 reverse transcription through the control of sterile α motif and HD domain-containing protein-1 (SAMHD1) activity

(2014) Eduardo Pauls et al.   AIDS

Cell Cycle Control and HIV-1 Susceptibility Are Linked by CDK6-Dependent CDK2 Phosphorylation of SAMHD1 in Myeloid and Lymphoid Cells

(2014) Eduardo Pauls et al.   JOURNAL OF IMMUNOLOGY

Cyclin-dependent kinases

(2014) Marcos Malumbres   GENOME BIOLOGY

A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

(2013) Kuang-Lei Tsai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inhibition of cdk9 during Herpes Simplex Virus 1 Infection Impedes Viral Transcription

(2013) Mark Ou et al.   PLoS One

Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1

(2013) Alexandra Cribier et al.   Cell Reports

Cyclin-Dependent Kinase 2 Phosphorylates S/T-P Sites in the Hepadnavirus Core Protein C-Terminal Domain and Is Incorporated into Viral Capsids

(2012) L. Ludgate et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus 1 ICP22 Inhibits the Transcription of Viral Gene Promoters by Binding to and Blocking the Recruitment of P-TEFb

(2012) Lei Guo et al.   PLoS One

CDK2 Regulates HIV-1 Transcription by Phosphorylation of CDK9 on Serine 90

(2012) Denitra Breuer et al.   Retrovirology

Crystal structure of HIV-1 Tat complexed with human P-TEFb

(2010) Tahir H. Tahirov et al.   NATURE

Cyclin-Dependent Kinase Activity Controls the Onset of the HCMV Lytic Cycle

(2010) Martin Zydek et al.   PLoS Pathogens

Cyclin Dependent Kinases as Attractive Targets to Prevent Transcription from Viral Genomes

(2009) Fatah Kashanchi et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular targets for antiviral therapy of cytomegalovirus infections

(2009) Manfred Marschall et al.   Future Microbiology

Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity

(2009) Sabine Rechter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multi-tasking P-TEFb complex

(2008) Vanessa Brès et al.   CURRENT OPINION IN CELL BIOLOGY

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

(2008) Sonja Baumli et al.   EMBO JOURNAL

CDK13, a New Potential Human Immunodeficiency Virus Type 1 Inhibitory Factor Regulating Viral mRNA Splicing

(2008) R. Berro et al.   JOURNAL OF VIROLOGY

Role of cdk9 in the Optimization of Expression of the Genes Regulated by ICP22 of Herpes Simplex Virus 1

(2008) L. O. Durand et al.   JOURNAL OF VIROLOGY

Cyclin T1-Dependent Genes in Activated CD4+ T and Macrophage Cell Lines Appear Enriched in HIV-1 Co-Factors

(2008) Wendong Yu et al.   PLoS One