A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction

Structure of the Mediator head module

(2012) Laurent Larivière et al.   NATURE

Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II

(2012) P. J. J. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of the Mediator Head Module with RNA Polymerase II

(2012) Gang Cai et al.   STRUCTURE

Iterative Stable Alignment and Clustering of 2D Transmission Electron Microscope Images

(2012) Zhengfan Yang et al.   STRUCTURE

The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder

(2011) E.V. Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

Architecture of the Mediator head module

(2011) Tsuyoshi Imasaki et al.   NATURE

Identifying Conformational States of Macromolecules by Eigen-Analysis of Resampled Cryo-EM Images

(2011) Pawel A. Penczek et al.   STRUCTURE

Molecular Architecture of the Human Mediator–RNA Polymerase II–TFIIF Assembly

(2011) Carrie Bernecky et al.   PLOS BIOLOGY

CDK8 is a positive regulator of transcriptional elongation within the serum response network

(2010) Aaron J Donner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mediator Head module structure and functional interactions

(2010) Gang Cai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

(2009) M. T. Knuesel et al.   GENES & DEVELOPMENT

DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy

(2009) N.R. Voss et al.   JOURNAL OF STRUCTURAL BIOLOGY

Conformational flexibility of metazoan fatty acid synthase enables catalysis

(2009) Edward J Brignole et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mediator Structural Conservation and Implications for the Regulation Mechanism

(2009) Gang Cai et al.   STRUCTURE

The Human CDK8 Subcomplex Is a Histone Kinase That Requires Med12 for Activity and Can Function Independently of Mediator

(2008) M. T. Knuesel et al.   MOLECULAR AND CELLULAR BIOLOGY