Exposure to perfluorooctane sulfonate reduced cell viability and insulin release capacity of β cells

Endothelial Nox5 Expression Modulates Glucose Uptake and Lipid Accumulation in Mice Fed a High-Fat Diet and 3T3-L1 Adipocytes Treated with Glucose and Palmitic Acid

(2021) Jorge G. García et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells via the Reactive Oxygen Species / JUN Pathway

(2021) Yaping Sun et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: Potential role of mTORC1-S6K1

(2021) Nadia Di Pietrantonio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Per- and polyfluoroalkyl substances in serum and associations with food consumption and use of personal care products in the Norwegian biomonitoring study from the EU project EuroMix

(2021) E. Thépaut et al.   ENVIRONMENTAL RESEARCH

Perfluorooctane sulfonate continual exposure impairs glucose-stimulated insulin secretion via SIRT1-induced upregulation of UCP2 expression

(2021) Xiaoyu Duan et al.   ENVIRONMENTAL POLLUTION

Chlorinated Polyfluoroalkylether Sulfonic Acids Exhibit Stronger Estrogenic Effects than Perfluorooctane Sulfonate by Activating Nuclear Estrogen Receptor Pathways

(2020) Yan Xin et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluoroalkyl Substances Stimulate Insulin Secretion by Islet β Cells via G Protein-Coupled Receptor 40

(2020) Wei-Ping Qin et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Albumin is the major carrier protein for PFOS, PFOA, PFHxS, PFNA and PFDA in human plasma

(2020) Martin Forsthuber et al.   ENVIRONMENT INTERNATIONAL

Probabilistic human health risk assessment of perfluorooctane sulfonate (PFOS) by integrating in vitro, in vivo toxicity, and human epidemiological studies using a Bayesian-based dose-response assessment coupled with physiologically based pharmacokinetic (PBPK) modeling approach

(2020) Wei-Chun Chou et al.   ENVIRONMENT INTERNATIONAL

Membrane/Water Partitioning and Permeabilities of Perfluoroalkyl Acids and Four of their Alternatives and the Effects on Toxicokinetic Behavior

(2020) Andrea Ebert et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Prenatal organophosphate pesticide exposure and reproductive hormones in cord blood in Shandong, China

(2020) Kaili Qin et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Associations of per- and polyfluoroalkyl substances (PFAS) with glucose tolerance during pregnancy in Project Viva

(2020) Emma V Preston et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cytotoxicity Burst? Differentiating Specific from Nonspecific Effects in Tox21 in Vitro Reporter Gene Assays

(2020) Beate I. Escher et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Serum perfluoroalkyl substances in residents following long-term drinking water contamination from firefighting foam in Ronneby, Sweden

(2020) Yiyi Xu et al.   ENVIRONMENT INTERNATIONAL

Endocrine Disrupting Chemicals: An Occult Mediator of Metabolic Disease

(2019) Olga Papalou et al.   Frontiers in Endocrinology

Occurrence of perfluoroalkyl substances (PFASs) in a large number of wild and farmed aquatic animals collected in the Netherlands

(2019) Effrosyni Zafeiraki et al.   CHEMOSPHERE

Assessing the human health risks of perfluorooctane sulfonate by in vivo and in vitro studies

(2019) Zhuotong Zeng et al.   ENVIRONMENT INTERNATIONAL

Effects of Aryl Hydrocarbon Receptor Deficiency on PCB-77-Induced Impairment of Glucose Homeostasis during Weight Loss in Male and Female Obese Mice

(2019) Erin N. Jackson et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Baseline Toxicity and Volatility Cutoff in Reporter Gene Assays Used for High-Throughput Screening

(2019) Beate I. Escher et al.   CHEMICAL RESEARCH IN TOXICOLOGY

EFFECTIVENESS OF A PRIMARY CARE NURSE DELIVERED EDUCATIONAL INTERVENTION FOR PATIENTS WITH TYPE 2 DIABETES MELLITUS IN PROMOTING METABOLIC CONTROL AND COMPLIANCE WITH LONG-TERM THERAPEUTIC TARGETS: RANDOMISED CONTROLLED TRIAL

(2019) M.C. De la Fuente Coria et al.   INTERNATIONAL JOURNAL OF NURSING STUDIES

ROS-mediated JNK pathway critically contributes to PFOS-triggered apoptosis in SH-SY5Y cells

(2019) Pingping Sun et al.   NEUROTOXICOLOGY AND TERATOLOGY

Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells

(2018) Yan Xin et al.   ARCHIVES OF TOXICOLOGY

Perfluoroalkyl substances and glycemic status in pregnant Danish women: The Odense Child Cohort

(2018) Richard Christian Jensen et al.   ENVIRONMENT INTERNATIONAL

Perfluoroalkyl substances, glucose homeostasis, and gestational diabetes mellitus in Chinese pregnant women: A repeat measurement-based prospective study

(2018) Hexing Wang et al.   ENVIRONMENT INTERNATIONAL

Chlorinated Polyfluorinated Ether Sulfonates Exhibit Higher Activity toward Peroxisome Proliferator-Activated Receptors Signaling Pathways than Perfluorooctanesulfonate

(2018) Chuan-Hai Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress

(2018) Zhenqi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic treatment with tributyltin induces sexually dimorphic alterations in the hypothalamic POMC system of adult mice

(2018) Alice Farinetti et al.   CELL AND TISSUE RESEARCH

Chlorinated Polyfluoroalkylether Sulfonates Exhibit Similar Binding Potency and Activity to Thyroid Hormone Transport Proteins and Nuclear Receptors as Perfluorooctanesulfonate

(2018) Yan Xin et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mitochondria as a target of endocrine-disrupting chemicals: implications for type 2 diabetes

(2018) Laura Marroqui et al.   JOURNAL OF ENDOCRINOLOGY

Perfluorobutanesulfonic acid disrupts pancreatic organogenesis and regulation of lipid metabolism in the zebrafish, Danio rerio

(2018) Karilyn E Sant et al.   TOXICOLOGICAL SCIENCES

Low-dose tributyltin exposure induces an oxidative stress-triggered JNK-related pancreatic β-cell apoptosis and a reversible hypoinsulinemic hyperglycemia in mice

(2018) Chun-Fa Huang et al.   Scientific Reports

Perfluorododecanoic Acid Blocks Rat Leydig Cell Development during Prepuberty

(2018) Yong Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Effect of endosulfan and bisphenol A on the expression of SUMO and UBC9

(2018) Vidhya Yarahalli Jayaram et al.   DRUG AND CHEMICAL TOXICOLOGY

Matrix-specific distribution and compositional profiles of perfluoroalkyl substances (PFASs) in multimedia environments

(2018) Sung-Hee Seo et al.   JOURNAL OF HAZARDOUS MATERIALS

Perfluoroalkyl substances and risk of type II diabetes: A prospective nested case-control study

(2018) Carolina Donat-Vargas et al.   ENVIRONMENT INTERNATIONAL

Distribution of Novel and Well-Known Poly- and Perfluoroalkyl Substances (PFASs) in Human Serum, Plasma, and Whole Blood

(2017) Somrutai Poothong et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tetrabromobisphenol A induces cellular damages in pancreatic β-cells in vitro

(2017) Kwang Sik Suh et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Perfluorooctanoic acid induces oxidative damage and mitochondrial dysfunction in pancreatic β-cells

(2017) Kwang Sik Suh et al.   Molecular Medicine Reports

BDE-47 causes developmental retardation with down-regulated expression profiles of ecdysteroid signaling pathway-involved nuclear receptor (NR) genes in the copepod Tigriopus japonicus

(2016) Dae-Sik Hwang et al.   AQUATIC TOXICOLOGY

Longitudinal Associations of Exposure to Perfluoroalkylated Substances in Childhood and Adolescence and Indicators of Adiposity and Glucose Metabolism 6 and 12 Years Later: The European Youth Heart Study

(2016) Sidsel L. Domazet et al.   DIABETES CARE

PFOS induces adipogenesis and glucose uptake in association with activation of Nrf2 signaling pathway

(2016) Jialin Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metabolically inert perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria

(2015) Irina G. Shabalina et al.   ARCHIVES OF TOXICOLOGY

Tissue Distribution and Whole Body Burden of the Chlorinated Polyfluoroalkyl Ether Sulfonic Acid F-53B in Crucian Carp (Carassius carassius): Evidence for a Highly Bioaccumulative Contaminant of Emerging Concern

(2015) Yali Shi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluorooctanoic acid exposure for 28 days affects glucose homeostasis and induces insulin hypersensitivity in mice

(2015) Shengmin Yan et al.   Scientific Reports

Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protection

(2014) Xia Sun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bisphenol A induces oxidative stress-associated DNA damage in INS-1 cells

(2014) Fei Xin et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Evaluation of the Association between Persistent Organic Pollutants (POPs) and Diabetes in Epidemiological Studies: A National Toxicology Program Workshop Review

(2013) Kyla W. Taylor et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Epigenetics: The missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes

(2012) Elizabeth R. Gilbert et al.   Epigenetics

P24—Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys

(2012) Shu-Ching Chang et al.   REPRODUCTIVE TOXICOLOGY

Evaluation of cellular response to perfluorooctane sulfonate in human umbilical vein endothelial cells

(2012) Yanyan Liao et al.   TOXICOLOGY IN VITRO

Testicular Signaling Is the Potential Target of Perfluorooctanesulfonate-Mediated Subfertility in Male Mice1

(2011) H.T. Wan et al.   BIOLOGY OF REPRODUCTION

Importance of Extranuclear Estrogen Receptor-  and Membrane G Protein-Coupled Estrogen Receptor in Pancreatic Islet Survival

(2009) S. Liu et al.   DIABETES

Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

(2009) R. A. DeFronzo et al.   DIABETES CARE

Immunotoxicity of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and the Role of Peroxisome Proliferator-Activated Receptor Alpha

(2008) Jamie C. DeWitt et al.   CRITICAL REVIEWS IN TOXICOLOGY

Transgenic Expression of Antioxidant Protein Thioredoxin in Pancreatic β Cells Prevents Progression of Type 2 Diabetes Mellitus

(2007) Mayu Yamamoto et al.   ANTIOXIDANTS & REDOX SIGNALING

Protection of pancreatic beta-cells: Is it feasible?

(2007) Enzo Bonora   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES