Perfluorooctane sulfonate continual exposure impairs glucose-stimulated insulin secretion via SIRT1-induced upregulation of UCP2 expression

Perfluoroalkyl Substances Stimulate Insulin Secretion by Islet β Cells via G Protein-Coupled Receptor 40

(2020) Wei-Ping Qin et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Comparative Analysis of PFOS and PFOA Toxicity on Sertoli Cells

(2020) Hin Ting Wan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Receptor-Bound Perfluoroalkyl Carboxylic Acids Dictate Their Activity on Human and Mouse Peroxisome Proliferator-Activated Receptor γ

(2020) Chuan-Hai Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluorooctane sulfonate acute exposure stimulates insulin secretion via GPR40 pathway

(2020) Lianying Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Profiling of emerging and legacy per-/polyfluoroalkyl substances in serum among pregnant women in China

(2020) Jiaying Liu et al.   ENVIRONMENTAL POLLUTION

Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines

(2019) John Bassler et al.   ENVIRONMENTAL POLLUTION

Perfluorohexanoic acid toxicity, part I: Development of a chronic human health toxicity value for use in risk assessment

(2019) Anthony L. Luz et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

SIRT1 Modulators in Experimentally Induced Liver Injury

(2019) Hassan Farghali et al.   Oxidative Medicine and Cellular Longevity

Perfluoroalkyl Acids (PFAAs) in Children’s Serum and Contribution from PFAA-Contaminated Drinking Water

(2019) Irina Gyllenhammar et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Occurrence and human exposure assessment of perfluorinated substances in house dust from three European countries

(2019) Adrián de la Torre et al.   SCIENCE OF THE TOTAL ENVIRONMENT

The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells

(2019) Baiyu Yao et al.   TOXICOLOGY LETTERS

Mitochondrial membrane potential

(2018) Ljubava D. Zorova et al.   ANALYTICAL BIOCHEMISTRY

Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells

(2018) Yan Xin et al.   ARCHIVES OF TOXICOLOGY

Do concentrations of perfluoroalkylated acids (PFAAs) in isopods reflect concentrations in soil and songbirds? A study using a distance gradient from a fluorochemical plant

(2018) Thimo Groffen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Variation in PFAA concentrations and egg parameters throughout the egg-laying sequence in a free-living songbird (the great tit, Parus major): Implications for biomonitoring studies

(2018) Robin Lasters et al.   ENVIRONMENTAL POLLUTION

Embryonic exposures to perfluorooctanesulfonic acid (PFOS) disrupt pancreatic organogenesis in the zebrafish, Danio rerio

(2017) Karilyn E. Sant et al.   ENVIRONMENTAL POLLUTION

Structure-Dependent Hematological Effects of Per- and Polyfluoroalkyl Substances on Activation of Plasma Kallikrein–Kinin System Cascade

(2017) Qian S. Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Perfluorooctanoic acid induces oxidative damage and mitochondrial dysfunction in pancreatic β-cells

(2017) Kwang Sik Suh et al.   Molecular Medicine Reports

Mitochondrial toxicity of perfluorooctane sulfonate in mouse embryonic stem cell-derived cardiomyocytes

(2017) Lei-Lei Tang et al.   TOXICOLOGY

PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling

(2017) Mitchell B. Rosen et al.   TOXICOLOGY

Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice

(2017) Nivedita Seshadri et al.   Molecular Metabolism

Serum perfluorinated chemicals, glucose homeostasis and the risk of diabetes in working-aged Taiwanese adults

(2016) Ta-Chen Su et al.   ENVIRONMENT INTERNATIONAL

Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by CysteineS-Nitrosation

(2016) Kelsey S. Kalous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of Sirt1 in mouse livers protects against endotoxemic liver injury by acetylating and activating NF-κB

(2016) Xiaolan Cui et al.   Cell Death & Disease

A review of sources, multimedia distribution and health risks of perfluoroalkyl acids (PFAAs) in China

(2015) Tieyu Wang et al.   CHEMOSPHERE

Differential Accumulation and Elimination Behavior of Perfluoroalkyl Acid Isomers in Occupational Workers in a Manufactory in China

(2015) Yan Gao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Toxic effects of perfluorononanoic acid on the development of Zebrafish (Danio rerio) embryos

(2015) Hui Liu et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Highly Elevated Serum Concentrations of Perfluoroalkyl Substances in Fishery Employees from Tangxun Lake, China

(2014) Zhen Zhou et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

ATP/ADP ratio, the missed connection between mitochondria and the Warburg effect

(2014) Eduardo N. Maldonado et al.   MITOCHONDRION

The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing

(2013) L. Luu et al.   DIABETOLOGIA

Circulating levels of perfluoroalkyl substances and prevalent diabetes in the elderly

(2013) Lars Lind et al.   DIABETOLOGIA

Persistence of Perfluoroalkyl Acid Precursors in AFFF-Impacted Groundwater and Soil

(2013) Erika F. Houtz et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells

(2013) Yedong Cheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

(2013) Xun Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo

(2013) Wan Norhamidah Wan Ibrahim et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anti-diabetic effects of Centratherum anthelminticum seeds methanolic fraction on pancreatic cells, β-TC6 and its alleviating role in type 2 diabetic rats

(2012) Aditya Arya et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cyclic AMP dynamics in the pancreatic β-cell

(2012) Anders Tengholm   UPSALA JOURNAL OF MEDICAL SCIENCES

Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate

(2011) Ziquan Lv et al.   ENVIRONMENTAL TOXICOLOGY

Mitochondrial ATP synthase: architecture, function and pathology

(2011) An I. Jonckheere et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Regulation of insulin secretion: role of mitochondrial signalling

(2010) S. Jitrapakdee et al.   DIABETOLOGIA

Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life☆

(2009) Erin P. Hines et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Metabolic cycling in control of glucose-stimulated insulin secretion

(2008) Mette V. Jensen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persistent Lipophilic Compounds

(2008) Jason M. Conder et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

UCP2 is highly expressed in pancreatic  -cells and influences secretion and survival

(2008) J. Diao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA