Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: Potential role of mTORC1-S6K1
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: Potential role of mTORC1-S6K1
Authors
Keywords
Childhood obesity, Endothelial dysfunction, Monocytes adhesion, Oxidative stress, Insulin resistance, Rapamycin
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Volume 1867, Issue 4, Pages 166076
Publisher
Elsevier BV
Online
2021-01-09
DOI
10.1016/j.bbadis.2021.166076
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Use of Human Umbilical Vein Endothelial Cells (HUVEC) as a Model to Study Cardiovascular Disease: A Review
- (2020) Diana J. Medina-Leyte et al. Applied Sciences-Basel
- Hormonal Blood Pressure Regulation during General Anesthesia Using a Standardized Propofol Dosage in Children and Adolescents Seems Not to Be Affected by Body Weight
- (2020) Gunther Hempel et al. Journal of Clinical Medicine
- Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species
- (2019) John J. Reho et al. Journal of the American Heart Association
- Targeting Early Atherosclerosis: A Focus on Oxidative Stress and Inflammation
- (2019) Patricia Marchio et al. Oxidative Medicine and Cellular Longevity
- Insulin Resistance in Children
- (2019) Veronica Maria Tagi et al. Frontiers in Endocrinology
- Unfolded Protein Response supports endothelial barrier function
- (2019) Nektarios Barabutis BIOCHIMIE
- The epidemiological burden of obesity in childhood: a worldwide epidemic requiring urgent action
- (2019) Mariachiara Di Cesare et al. BMC Medicine
- ER Stress Activates the NLRP3 Inflammasome: A Novel Mechanism of Atherosclerosis
- (2019) Xinnong Chen et al. Oxidative Medicine and Cellular Longevity
- Urinary Biomarkers of Inflammation and Oxidative Stress Are Elevated in Obese Children and Correlate with a Marker of Endothelial Dysfunction
- (2019) Vaithinathan Selvaraju et al. Oxidative Medicine and Cellular Longevity
- P53 Regulates the Redox Status of Lung Endothelial Cells
- (2019) Mohammad S. Akhter et al. INFLAMMATION
- Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases
- (2018) Maria Angela Incalza et al. VASCULAR PHARMACOLOGY
- Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm
- (2018) Andrew M. South et al. JOURNAL OF PEDIATRICS
- Review of Childhood Obesity
- (2017) Seema Kumar et al. MAYO CLINIC PROCEEDINGS
- Plasma from pre-pubertal obese children impairs insulin stimulated Nitric Oxide (NO) bioavailability in endothelial cells: Role of ER stress
- (2017) Natalia Di Pietro et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling
- (2017) Mee-Sup Yoon Nutrients
- Akt/mTOR Role in Human Foetoplacental Vascular Insulin Resistance in Diseases of Pregnancy
- (2017) Roberto Villalobos-Labra et al. Journal of Diabetes Research
- Pharmacological inhibition of S6K1 increases glucose metabolism and Akt signalling in vitro and in diet-induced obese mice
- (2016) Michael Shum et al. DIABETOLOGIA
- Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives
- (2016) Pei Shi Ong et al. Frontiers in Pharmacology
- Endothelial progenitor cells, defined by the simultaneous surface expression of VEGFR2 and CD133, are not detectable in healthy peripheral and cord blood
- (2015) Paola Lanuti et al. CYTOMETRY PART A
- Rapamycin: One Drug, Many Effects
- (2014) Jing Li et al. Cell Metabolism
- Inhibitory cross-talk between the AMPK and ERK pathways mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle
- (2013) Seung-Lark Hwang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Childhood Obesity and Cardiovascular Dysfunction
- (2013) Anita T. Cote et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Role of insulin resistance in endothelial dysfunction
- (2013) Ranganath Muniyappa et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet
- (2013) O V Leontieva et al. Cell Death & Disease
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- β-Carotene and lycopene affect endothelial response to TNF-α reducing nitro-oxidative stress and interaction with monocytes
- (2011) Pamela Di Tomo et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Endothelial dysfunction, inflammation, and oxidative stress in obese children and adolescents: markers and effect of lifestyle intervention
- (2011) D. Montero et al. Obesity Reviews
- Inflammatory Adipokines, High Molecular Weight Adiponectin, and Insulin Resistance: A Population-Based Survey in Prepubertal Schoolchildren
- (2011) Giuseppe Murdolo et al. PLoS One
- Hyperactive S6K1 Mediates Oxidative Stress and Endothelial Dysfunction in Aging: Inhibition by Resveratrol
- (2011) Angana G. Rajapakse et al. PLoS One
- Unbalanced oxidant–antioxidant status and its effects in pediatric diseases
- (2011) Valentina Chiavaroli et al. REDOX REPORT
- Oxidant mechanisms in childhood obesity: the link between inflammation and oxidative stress
- (2011) Pilar Codoñer-Franch et al. Translational Research
- The TRIB3 R84 variant is associated with increased carotid intima–media thickness in vivo and with enhanced MAPK signalling in human endothelial cells
- (2010) Gloria Formoso et al. CARDIOVASCULAR RESEARCH
- Crosstalk of reactive oxygen species and NF-κB signaling
- (2010) Michael J Morgan et al. CELL RESEARCH
- Vascular actions of insulin with implications for endothelial dysfunction
- (2009) Maria Assunta Potenza et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- ENPP1 Q121 Variant, Increased Pulse Pressure and Reduced Insulin Signaling, and Nitric Oxide Synthase Activity in Endothelial Cells
- (2009) Simonetta Bacci et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Increased carotid intima-media thickness in pre-pubertal children with constitutional leanness and severe obesity: the speculative role of insulin sensitivity, oxidant status, and chronic inflammation
- (2009) C Giannini et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Raptor Binds the SAIN (Shc and IRS-1 NPXY Binding) Domain of Insulin Receptor Substrate-1 (IRS-1) and Regulates the Phosphorylation of IRS-1 at Ser-636/639 by mTOR
- (2009) Alexandros Tzatsos JOURNAL OF BIOLOGICAL CHEMISTRY
- Insulin Resistance Affects Gene Expression in Endothelium
- (2008) Claudia Consoli et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells
- (2008) Francesco Andreozzi et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Obesity reduces the bioavailability of nitric oxide in juveniles
- (2008) H-J Gruber et al. INTERNATIONAL JOURNAL OF OBESITY
- S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2
- (2008) Jin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Obese related effects of inflammatory markers and insulin resistance on increased carotid intima media thickness in pre-pubertal children
- (2007) Cosimo Giannini et al. ATHEROSCLEROSIS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started