Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot

Genetically Encoded Elastin‐Like Polypeptides for Drug Delivery

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Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Radiotherapy‐immunotherapy combinations: perspectives and challenges

(2020) Michele Mondini et al.   Molecular Oncology

Development of elastin-like polypeptide for targeted specific gene delivery in vivo

(2020) Aena Yi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Immunostimulant Complexed With Polylysine Limits Transport and Maintains Immune Cell Activation

(2020) Melissa M. Pressnall et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Radiotherapy Cooperates with IL15 to Induce Antitumor Immune Responses

(2020) Karsten A. Pilones et al.   Cancer Immunology Research

Enhanced cellular uptake of CpG DNA by α-helical antimicrobial peptide Kn2-7: Effects on macrophage responsiveness to CpG DNA

(2020) Saeka Nishihara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alginate-based hydrogels for cancer therapy and research

(2020) Belen Reig-Vano et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Conjugate of Doxorubicin to Albumin‐Binding Peptide Outperforms Aldoxorubicin

(2019) Parisa Yousefpour et al.   Small

Effect of Pembrolizumab After Stereotactic Body Radiotherapy vs Pembrolizumab Alone on Tumor Response in Patients With Advanced Non–Small Cell Lung Cancer

(2019) Willemijn S. M. E. Theelen et al.   JAMA Oncology

Are 90% of deaths from cancer caused by metastases?

(2019) Hanna Dillekås et al.   Cancer Medicine

Tumor‐Targeted Drug and CpG Delivery System for Phototherapy and Docetaxel‐Enhanced Immunotherapy with Polarization toward M1‐Type Macrophages on Triple Negative Breast Cancers

(2019) Lv Chen et al.   ADVANCED MATERIALS

Robo1-specific CAR-NK Immunotherapy Enhances Efficacy of 125I Seed Brachytherapy in an Orthotopic Mouse Model of Human Pancreatic Carcinoma

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A phase 2 clinical trial assessing the efficacy and safety of pembrolizumab and radiotherapy in patients with metastatic triple‐negative breast cancer

(2019) Alice Y. Ho et al.   CANCER

Statistical determination of synergy based on Bliss definition of drugs independence

(2019) Eugene Demidenko et al.   PLoS One

Immunotherapy and pulmonary toxicities: can concomitant immune-checkpoint inhibitors with radiotherapy increase the risk of radiation pneumonitis?

(2018) Guillaume Louvel et al.   EUROPEAN RESPIRATORY JOURNAL

ε-Poly- l -Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo

(2018) Haimanti Mandal et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action

(2018) Caslin A. Gilroy et al.   JOURNAL OF CONTROLLED RELEASE

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

Immune-checkpoint inhibitors associated with interstitial lung disease in cancer patients

(2017) Myriam Delaunay et al.   EUROPEAN RESPIRATORY JOURNAL

One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer

(2017) Kelli M. Luginbuhl et al.   Nature Biomedical Engineering

Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy

(2016) Jeffrey L. Schaal et al.   JOURNAL OF CONTROLLED RELEASE

Elastin-like recombinamers with acquired functionalities for gene-delivery applications

(2015) Maria J. Piña et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

(2015) Christina Twyman-Saint Victor et al.   NATURE

Stapling monomeric GCN4 peptides allows for DNA binding and enhanced cellular uptake

(2015) Abhishek Iyer et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Uniform Small Graphene Oxide as an Efficient Cellular Nanocarrier for Immunostimulatory CpG Oligonucleotides

(2014) Jinli Sun et al.   ACS Applied Materials & Interfaces

Applications of elastin-like polypeptides in drug delivery

(2014) Sarah R. MacEwan et al.   JOURNAL OF CONTROLLED RELEASE

Injectable, self-gelling, biodegradable, and immunomodulatory DNA hydrogel for antigen delivery

(2014) Makiya Nishikawa et al.   JOURNAL OF CONTROLLED RELEASE

Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial

(2014) Eugene D Kwon et al.   LANCET ONCOLOGY

A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection

(2013) M. Amiram et al.   JOURNAL OF CONTROLLED RELEASE

Abscopal Regression of Antigen Disparate Tumors by Antigen Cascade After Systemic Tumor Vaccination in Combination with Local Tumor Radiation

(2012) James W. Hodge et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Brachytherapy Using Injectable Seeds That Are Self-Assembled from Genetically Encoded Polypeptides In Situ

(2012) W. Liu et al.   CANCER RESEARCH

CpG plus radiotherapy: a review of preclinical works leading to clinical trial

(2012) Kathy A. Mason et al.   Frontiers in Oncology

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Recursive Directional Ligation by Plasmid Reconstruction Allows Rapid and Seamless Cloning of Oligomeric Genes

(2010) Jonathan R. McDaniel et al.   BIOMACROMOLECULES

Cellular uptake of self-assembled cationic peptide–DNA complexes: Multifunctional role of the enhancer chloroquine

(2009) Shu Yang et al.   JOURNAL OF CONTROLLED RELEASE

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors

(2008) Yuki Hori et al.   Acta Biomaterialia