Glycation modulates alpha-synuclein fibrillization kinetics: A sweet spot for inhibition
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Title
Glycation modulates alpha-synuclein fibrillization kinetics: A sweet spot for inhibition
Authors
Keywords
Parkinson's disease, glycation, neurodegenerative diseases, alpha-Synuclein
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 298, Issue 5, Pages 101848
Publisher
Elsevier BV
Online
2022-03-18
DOI
10.1016/j.jbc.2022.101848
References
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Note: Only part of the references are listed.- Comparison of N-Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α-Synuclein Aggregation
- (2021) Ana Galesic et al. ACS Chemical Biology
- Internalization of α-synuclein oligomers into SH-SY5Y cells
- (2021) Lindsay J. Shearer et al. BIOPHYSICAL JOURNAL
- Effects of α-Synuclein-Associated Post-Translational Modifications in Parkinson’s Disease
- (2021) Songzhe He et al. ACS Chemical Neuroscience
- Galactose in human metabolism, glycosylation and congenital metabolic diseases: Time for a closer look
- (2021) Federica Conte et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Do Post-Translational Modifications Influence Protein Aggregation in Neurodegenerative Diseases: A Systematic Review
- (2020) Larissa-Nele Schaffert et al. Brain Sciences
- Modification by glyceraldehyde-3-phosphate prevents amyloid transformation of alpha-synuclein
- (2019) Kseniya Barinova et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity
- (2019) Hossein Mohammad-Beigi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease
- (2019) Neelam Sharma et al. FREE RADICAL BIOLOGY AND MEDICINE
- Glycation of α-synuclein amplifies the binding with glyceraldehyde-3-phosphate dehydrogenase
- (2019) Pavel Semenyuk et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles
- (2019) Richard M. Meade et al. Molecular Neurodegeneration
- α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities
- (2019) Parvez Alam et al. JOURNAL OF NEUROCHEMISTRY
- The growth of amyloid fibrils: rates and mechanisms
- (2019) Alexander K. Buell BIOCHEMICAL JOURNAL
- Glycation affects fibril formation of Aβ peptides
- (2018) Alesandro Emendato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson’s Disease
- (2018) Annekatrin König et al. Journal of Parkinsons Disease
- Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy
- (2018) Yaowang Li et al. CELL RESEARCH
- Cellular models as tools for the study of the role of alpha-synuclein in Parkinson's disease
- (2017) Diana F. Lázaro et al. EXPERIMENTAL NEUROLOGY
- The status of glycation in protein aggregation
- (2017) Fereshteh Taghavi et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Probing Protein Glycation by Chromatography and Mass Spectrometry: Analysis of Glycation Adducts
- (2017) Alena Soboleva et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases
- (2017) Kyunghee Byun et al. PHARMACOLOGY & THERAPEUTICS
- Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification
- (2017) Ricardo Gaspar et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Guanine glycation repair by DJ-1/Park7 and its bacterial homologs
- (2017) Gilbert Richarme et al. SCIENCE
- Evolution of Complex Maillard Chemical Reactions, Resolved in Time
- (2017) Daniel Hemmler et al. Scientific Reports
- Cell Biology and Pathophysiology of α-Synuclein
- (2017) Jacqueline Burré et al. Cold Spring Harbor Perspectives in Medicine
- The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson’s Disease
- (2017) Céline Galvagnion Journal of Parkinsons Disease
- Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson’s disease
- (2017) Hugo Vicente Miranda et al. Scientific Reports
- Lysines, Achilles’ heel in alpha-synuclein conversion to a deadly neuronal endotoxin
- (2016) Nicoletta Plotegher et al. AGEING RESEARCH REVIEWS
- DJ-1 linked parkinsonism (PARK7) is associated with Lewy body pathology
- (2016) Ricardo Taipa et al. BRAIN
- Pathways of the Maillard reaction under physiological conditions
- (2016) Christian Henning et al. GLYCOCONJUGATE JOURNAL
- Toxicity of serum albumin on microglia upon seeding effect of amyloid peptide
- (2016) Maryam Ferdousi et al. JOURNAL OF BIOCHEMISTRY
- Glycation in Parkinson's disease and Alzheimer's disease
- (2016) Hugo Vicente Miranda et al. MOVEMENT DISORDERS
- Molecular mechanisms of protein aggregation from global fitting of kinetic models
- (2016) Georg Meisl et al. Nature Protocols
- Glycation induces conformational changes in the amyloid-β peptide and enhances its aggregation propensity: molecular insights
- (2016) Asis K. Jana et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Nuclear Magnetic Resonance Analysis of the Acetylation Pattern of the Neuronal Tau Protein
- (2014) Amina Kamah et al. BIOCHEMISTRY
- Parkinsonism-associated Protein DJ-1/Park7 Is a Major Protein Deglycase That Repairs Methylglyoxal- and Glyoxal-glycated Cysteine, Arginine, and Lysine Residues
- (2014) Gilbert Richarme et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Advanced Glycation End Products and Diabetic Complications
- (2014) Varun Parkash Singh et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- Solution conditions determine the relative importance of nucleation and growth processes in -synuclein aggregation
- (2014) A. K. Buell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour
- (2014) Giuliana Fusco et al. Nature Communications
- Fructose compared with glucose is more a potent glycoxidation agent in vitro, but not under carbohydrate-induced stress in vivo: potential role of antioxidant and antiglycation enzymes
- (2013) Halyna M. Semchyshyn et al. CARBOHYDRATE RESEARCH
- Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation
- (2013) G. Vistoli et al. FREE RADICAL RESEARCH
- d-ribose in glycation and protein aggregation
- (2012) Yan Wei et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Insights into the molecular mechanism of protein native-like aggregation upon glycation
- (2012) Luis M.A. Oliveira et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications
- (2012) R. Nagai et al. DIABETES
- Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation
- (2012) M. J. Diogenes et al. JOURNAL OF NEUROSCIENCE
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glyoxalase in diabetes, obesity and related disorders
- (2011) Naila Rabbani et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Modulation of Amyloid β Peptide1-42 Cytotoxicity and Aggregation in Vitro by Glucose and Chondroitin Sulfate
- (2010) X. Fernandez-Busquets et al. Current Alzheimer Research
- Immunological detection of fructose-derived advanced glycation end-products
- (2010) Masayoshi Takeuchi et al. LABORATORY INVESTIGATION
- The Influence of Vesicle Size and Composition on α-Synuclein Structure and Stability
- (2009) Lars Kjaer et al. BIOPHYSICAL JOURNAL
- Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells
- (2009) Yan Wei et al. BMC CELL BIOLOGY
- Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models
- (2009) Damla Pinar Karpinar et al. EMBO JOURNAL
- Inducible over-expression of wild type α-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death
- (2009) Kostas Vekrellis et al. JOURNAL OF NEUROCHEMISTRY
- The sour side of neurodegenerative disorders: the effects of protein glycation
- (2009) Hugo Vicente Miranda et al. JOURNAL OF PATHOLOGY
- The modification of α-synuclein by dicarbonyl compounds inhibits its fibril-forming process
- (2008) Daekyun Lee et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Assembly-dependent endocytosis and clearance of extracellular a-synuclein
- (2008) He-Jin Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- A Perspective on the Maillard Reaction and the Analysis of Protein Glycation by Mass Spectrometry: Probing the Pathogenesis of Chronic Disease
- (2008) Qibin Zhang et al. JOURNAL OF PROTEOME RESEARCH
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