α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities
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Title
α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities
Authors
Keywords
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Journal
JOURNAL OF NEUROCHEMISTRY
Volume 150, Issue 5, Pages 522-534
Publisher
Wiley
Online
2019-06-29
DOI
10.1111/jnc.14808
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Note: Only part of the references are listed.- Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network
- (2019) Simona Gribaudo et al. Stem Cell Reports
- Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation
- (2019) Femke van Diggelen et al. PLoS One
- Hydrophobic-Interaction-Induced Stiffening of α -Synuclein Fibril Networks
- (2018) Slav A. Semerdzhiev et al. PHYSICAL REVIEW LETTERS
- Cryo-EM structure of alpha-synuclein fibrils
- (2018) Ricardo Guerrero-Ferreira et al. eLife
- Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy
- (2018) Yaowang Li et al. CELL RESEARCH
- Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel
- (2018) Binsen Li et al. Nature Communications
- α-Synuclein promotes dilation of the exocytotic fusion pore
- (2017) Todd Logan et al. NATURE NEUROSCIENCE
- Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
- (2017) Giuliana Fusco et al. SCIENCE
- Propagation of pathological α-synuclein in marmoset brain
- (2017) Aki Shimozawa et al. Acta Neuropathologica Communications
- Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease
- (2016) Emma Deas et al. ANTIOXIDANTS & REDOX SIGNALING
- Alpha-synuclein activates BV2 microglia dependent on its aggregation state
- (2016) Alana Hoffmann et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Widespread transneuronal propagation of α-synucleinopathy triggered in olfactory bulb mimics prodromal Parkinson’s disease
- (2016) Nolwen L. Rey et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structural disorder of monomeric α-synuclein persists in mammalian cells
- (2016) Francois-Xavier Theillet et al. NATURE
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein
- (2016) Marcus D Tuttle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Alpha-Synuclein Oligomers—Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders
- (2016) Martin Ingelsson Frontiers in Neuroscience
- Structural and functional properties of prefibrillar α-synuclein oligomers
- (2016) Laura Pieri et al. Scientific Reports
- Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease
- (2015) A. Gustot et al. BIOCHEMICAL JOURNAL
- Post-translational modification of α-synuclein in Parkinson׳s disease
- (2015) Paul J. Barrett et al. BRAIN RESEARCH
- Insights on the interaction of alpha-synuclein and metals in the pathophysiology of Parkinson's disease
- (2015) Eleonora Carboni et al. Metallomics
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
- (2015) Stanley B. Prusiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson’s disease
- (2015) Paula Garcia-Esparcia et al. Acta Neuropathologica Communications
- Co-existence of Two Different α-Synuclein Oligomers with Different Core Structures Determined by Hydrogen/Deuterium Exchange Mass Spectrometry
- (2014) Wojciech Paslawski et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cold Denaturation of α-Synuclein Amyloid Fibrils
- (2014) Tatsuya Ikenoue et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- High Stability and Cooperative Unfolding of α-Synuclein Oligomers
- (2014) Wojciech Paslawski et al. BIOCHEMISTRY
- How Epigallocatechin Gallate Can Inhibit α-Synuclein Oligomer Toxicityin Vitro
- (2014) Nikolai Lorenzen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Insights into Amyloid Oligomers of the Parkinson Disease-related Protein α-Synuclein
- (2014) J. Ignacio Gallea et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein-Induced Membrane Remodeling Is Driven by Binding Affinity, Partition Depth, and Interleaflet Order Asymmetry
- (2014) Anthony R. Braun et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid Formation
- (2014) Nikolai Lorenzen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Polyunsaturated fatty acids and their metabolites in brain function and disease
- (2014) Richard P. Bazinet et al. NATURE REVIEWS NEUROSCIENCE
- Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice
- (2014) Veronica Lindström et al. NEUROBIOLOGY OF DISEASE
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice
- (2013) Nolwen L. Rey et al. ACTA NEUROPATHOLOGICA
- G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
- (2013) Suzanne Lesage et al. ANNALS OF NEUROLOGY
- Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
- (2013) Ariadna Recasens et al. ANNALS OF NEUROLOGY
- Prion-like spreading of pathological α-synuclein in brain
- (2013) Masami Masuda-Suzukake et al. BRAIN
- α-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling
- (2013) Myriam M. Ouberai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toward the Molecular Mechanism(s) by Which EGCG Treatment Remodels Mature Amyloid Fibrils
- (2013) Fernando L. Palhano et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Properties of native brain α-synuclein
- (2013) Jacqueline Burré et al. NATURE
- A novel -synuclein missense mutation in Parkinson disease
- (2013) C. Proukakis et al. NEUROLOGY
- Transmission of multiple system atrophy prions to transgenic mice
- (2013) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Large -synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
- (2013) B.-K. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure
- (2012) María Soledad Celej et al. BIOCHEMICAL JOURNAL
- Fibrillar α-Synuclein and Huntingtin Exon 1 Assemblies Are Toxic to the Cells
- (2012) Laura Pieri et al. BIOPHYSICAL JOURNAL
- Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
- (2012) Nunilo Cremades et al. CELL
- Remodeling of Lipid Vesicles into Cylindrical Micelles by α-Synuclein in an Extended α-Helical Conformation
- (2012) Naoko Mizuno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Accumulation of Toxic -Synuclein Oligomer within Endoplasmic Reticulum Occurs in -Synucleinopathy In Vivo
- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
- α-Synuclein Induces Both Positive Mean Curvature and Negative Gaussian Curvature in Membranes
- (2012) Anthony R. Braun et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- α-Synuclein Oligomers: an Amyloid Pore?
- (2012) Martin T. Stöckl et al. MOLECULAR NEUROBIOLOGY
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Interplay between desolvation and secondary structure in mediating cosolvent and temperature induced alpha-synuclein aggregation
- (2012) V L Anderson et al. PHYSICAL BIOLOGY
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Structural and Morphological Characterization of Aggregated Species of α-Synuclein Induced by Docosahexaenoic Acid
- (2011) Giorgia De Franceschi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding
- (2011) Iwona M. Pranke et al. JOURNAL OF CELL BIOLOGY
- Pathological roles of α-synuclein in neurological disorders
- (2011) Kostas Vekrellis et al. LANCET NEUROLOGY
- Prion-like acceleration of a synucleinopathy in a transgenic mouse model
- (2011) Anne-Laure Mougenot et al. NEUROBIOLOGY OF AGING
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Low-resolution structure of a vesicle disrupting -synuclein oligomer that accumulates during fibrillation
- (2011) L. Giehm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel molecular mechanism for nitrated α-synuclein-induced cell death
- (2011) Yanying Liu et al. Journal of Molecular Cell Biology
- The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties
- (2010) Thomas Näsström et al. FREE RADICAL BIOLOGY AND MEDICINE
- Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins
- (2010) Jobin Varkey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Copper binding regulates intracellular alpha-synuclein localisation, aggregation and toxicity
- (2010) Xiaoyan Wang et al. JOURNAL OF NEUROCHEMISTRY
- Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits -Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions
- (2010) K. E. Paleologou et al. JOURNAL OF NEUROSCIENCE
- Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells
- (2009) Mordhwaj S. Parihar et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents
- (2009) Songcang Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Tryptophan Fluorescence Reveals Structural Features of α-Synuclein Oligomers
- (2009) B.D. van Rooijen et al. JOURNAL OF MOLECULAR BIOLOGY
- Seeding induced by α-synuclein oligomers provides evidence for spreading of α-synuclein pathology
- (2009) Karin M. Danzer et al. JOURNAL OF NEUROCHEMISTRY
- Interplay of -synuclein binding and conformational switching probed by single-molecule fluorescence
- (2009) A. C. M. Ferreon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: Conformational heterogeneity of α-synuclein
- (2009) Agya K. Frimpong et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Single Particle Characterization of Iron-induced Pore-forming α-Synuclein Oligomers
- (2008) Marcus Kostka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
- (2008) Dagmar E Ehrnhoefer et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level
- (2008) Massimo Sandal et al. PLOS BIOLOGY
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