mTORC1 inhibitor effects on rapid ketamine-induced reductions in suicidal ideation in patients with treatment-resistant depression

Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin

(2020) Chadi G. Abdallah et al.   NEUROPSYCHOPHARMACOLOGY

The potential role of the HCN1 ion channel and BDNF-mTOR signaling pathways and synaptic transmission in the alleviation of PTSD

(2020) Lianghui Ni et al.   Translational Psychiatry

Acute exercise enhances fear extinction through a mechanism involving central mTOR signaling

(2020) Nicolette A. Moya et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Prediction Models for Suicide Attempts and Deaths

(2019) Bradley E. Belsher et al.   JAMA Psychiatry

Suicide Reduction and Research Efforts in Service Members and Veterans—Sobering Realities

(2019) Charles W. Hoge   JAMA Psychiatry

Critical appraisal of major depression with suicidal ideation

(2019) Maurizio Pompili   Annals of General Psychiatry

Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials

(2019) Katrina Witt et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial

(2018) Michael F. Grunebaum et al.   AMERICAN JOURNAL OF PSYCHIATRY

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

(2018) Samuel T. Wilkinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Depression and hopelessness as risk factors for suicide ideation, attempts and death: meta-analysis of longitudinal studies

(2018) Jessica D. Ribeiro et al.   BRITISH JOURNAL OF PSYCHIATRY

The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

(2018) Chadi G. Abdallah et al.   PHARMACOLOGY & THERAPEUTICS

Antisuicidal Effects in Mood Disorders: Are They Unique to Lithium?

(2018) Leonardo Tondo et al.   PHARMACOPSYCHIATRY

Understanding suicide: Focusing on its mechanisms through a lithium lens

(2018) Gin S Malhi et al.   JOURNAL OF AFFECTIVE DISORDERS

Molecular Pharmacology and Neurobiology of Rapid-Acting Antidepressants

(2018) Todd D. Gould et al.   Annual Review of Pharmacology and Toxicology

Clozapine induced gastrointestinal hypomotility: A potentially life threatening adverse event. A review of the literature

(2017) Stephen West et al.   GENERAL HOSPITAL PSYCHIATRY

Clozapine and incidence of myocarditis and sudden death – Long term Australian experience

(2017) Arshad A. Khan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Targeting glutamate signalling in depression: progress and prospects

(2017) James W. Murrough et al.   NATURE REVIEWS DRUG DISCOVERY

Gene expression associated with suicide attempts in US veterans

(2017) J D Flory et al.   Translational Psychiatry

New perspectives on the involvement of mTOR in depression as well as in the action of antidepressant drugs

(2016) Zuleide M. Ignácio et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation

(2016) M M Harraz et al.   MOLECULAR PSYCHIATRY

Ketamine as a promising prototype for a new generation of rapid-acting antidepressants

(2015) Chadi G. Abdallah et al.   Annals of the New York Academy of Sciences

Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics

(2015) Chadi G. Abdallah et al.   Annual Review of Medicine

Mental disorders and risk of suicide attempt: a national prospective study

(2015) N Hoertel et al.   MOLECULAR PSYCHIATRY

Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach

(2015) A B Niculescu et al.   MOLECULAR PSYCHIATRY

Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial

(2015) J. W. Murrough et al.   PSYCHOLOGICAL MEDICINE

Roles of mTOR Signaling in Brain Development

(2015) Da Yong Lee   Experimental Neurobiology

Existing and Novel Biological Therapeutics in Suicide Prevention

(2014) Joshua J. Griffiths et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

EFFECTS OF KETAMINE ON EXPLICIT AND IMPLICIT SUICIDAL COGNITION: A RANDOMIZED CONTROLLED TRIAL IN TREATMENT-RESISTANT DEPRESSION

(2014) Rebecca B. Price et al.   DEPRESSION AND ANXIETY

Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

(2013) James W. Murrough et al.   AMERICAN JOURNAL OF PSYCHIATRY

Inhibition of mTOR kinase via rapamycin blocks persistent predator stress-induced hyperarousal

(2013) Kathleen Fifield et al.   BEHAVIOURAL BRAIN RESEARCH

Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex

(2013) W. Zhou et al.   EUROPEAN PSYCHIATRY

A recollection of mTOR signaling in learning and memory

(2013) T. E. Graber et al.   LEARNING & MEMORY

Ketamine for Depression: Where Do We Go from Here?

(2012) Marije aan het Rot et al.   BIOLOGICAL PSYCHIATRY

Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial

(2012) Carlos A. Zarate et al.   BIOLOGICAL PSYCHIATRY

Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

(2012) James W. Murrough et al.   BIOLOGICAL PSYCHIATRY

Acute administration of ketamine in rats increases hippocampal BDNF and mTOR levels during forced swimming test

(2012) Chun Yang et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

(2011) Nanxin Li et al.   BIOLOGICAL PSYCHIATRY

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder

(2011) Courtney S. Jernigan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

(2010) Nancy DiazGranados et al.   JOURNAL OF CLINICAL PSYCHIATRY

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Effects of Intravenous Ketamine on Explicit and Implicit Measures of Suicidality in Treatment-Resistant Depression

(2009) Rebecca B. Price et al.   BIOLOGICAL PSYCHIATRY

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Lithium's Antisuicidal Efficacy: Elucidation of Neurobiological Targets Using Endophenotype Strategies

(2008) Colleen E. Kovacsics et al.   Annual Review of Pharmacology and Toxicology