Polyploidy as a Fundamental Phenomenon in Evolution, Development, Adaptation and Diseases
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Title
Polyploidy as a Fundamental Phenomenon in Evolution, Development, Adaptation and Diseases
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 7, Pages 3542
Publisher
MDPI AG
Online
2022-03-26
DOI
10.3390/ijms23073542
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Note: Only part of the references are listed.- A Neonatal Mild Defect in Brain Insulin Signaling Predisposes a Subclinical Model of Sporadic Alzheimer's to Develop the Disease
- (2021) Zohreh Abbasi et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- CELL CYCLE STRESS IN NORMAL HUMAN CELLS: A ROUTE TO “FIRST CELLS” (WITH/WITHOUT FITNESS GAIN) AND CANCER-LIKE CELL-SHAPE CHANGES
- (2021) Kirsten H Walen SEMINARS IN CANCER BIOLOGY
- Developmental and Early Life Origins of Cardiometabolic Risk Factors
- (2021) Empar Lurbe et al. HYPERTENSION
- Whole-genome doubling confers unique genetic vulnerabilities on tumour cells
- (2021) Ryan J. Quinton et al. NATURE
- Cancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells
- (2021) K. J. Pienta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver
- (2021) Heng Lin et al. Nature Communications
- Proliferative polyploid cells give rise to tumors via ploidy reduction
- (2021) Tomonori Matsumoto et al. Nature Communications
- Altered chromatin conformation and transcriptional regulation in watermelon following genome doubling
- (2021) Marleny Garcia‐Lozano et al. PLANT JOURNAL
- Ploidy dynamics increase the risk of liver cancer initiation
- (2021) Miryam Müller et al. Nature Communications
- Polyploid cardiomyocytes: implications for heart regeneration
- (2021) Anna Kirillova et al. DEVELOPMENT
- Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond
- (2021) Luís F. Grilo et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Polyploidy in Tissue Repair and Regeneration
- (2021) Erin C. Bailey et al. Cold Spring Harbor Perspectives in Biology
- Context-dependent effects of whole-genome duplication during mammary tumor recurrence
- (2021) Rachel Newcomb et al. Scientific Reports
- Cell Cycle Re-entry in the Nervous System: From Polyploidy to Neurodegeneration
- (2021) Shyama Nandakumar et al. Frontiers in Cell and Developmental Biology
- Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome
- (2021) Markus Krane et al. CIRCULATION
- Growth of Biological Complexity from Prokaryotes to Hominids Reflected in the Human Genome
- (2021) Alexander E. Vinogradov et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetic Modifications at the Center of the Barker Hypothesis and Their Transgenerational Implications
- (2021) Rebecca Jean Ryznar et al. International Journal of Environmental Research and Public Health
- DNA Damage Responses during the Cell Cycle: Insights from Model Organisms and Beyond
- (2021) Delisa E. Clay et al. Genes
- Diversity of Nuclear Lamin A/C Action as a Key to Tissue-Specific Regulation of Cellular Identity in Health and Disease
- (2021) Anna Malashicheva et al. Frontiers in Cell and Developmental Biology
- Polyploidy in Cardiomyocytes
- (2020) Wouter Derks et al. CIRCULATION RESEARCH
- Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration
- (2020) Lu Han et al. DEVELOPMENTAL CELL
- Cell‐cycle dependence of transcriptome gene modules: comparison of regression lines
- (2020) Alexander E. Vinogradov et al. FEBS Journal
- Cell Fusion-Mediated Tissue Regeneration as an Inducer of Polyploidy and Aneuploidy
- (2020) Jessica Dörnen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Competition of Parental Genomes in Plant Hybrids
- (2020) Marek Glombik et al. Frontiers in Plant Science
- Sensitivity to gene dosage and gene expression affects genes with copy number variants observed among neuropsychiatric diseases
- (2020) Maria Yamasaki et al. BMC Medical Genomics
- Polyploidy in liver development, homeostasis and disease
- (2020) Romain Donne et al. Nature Reviews Gastroenterology & Hepatology
- Role of cell cycling and polyploidy in placental trophoblast of different mammalian species
- (2020) Tatiana G. Zybina et al. REPRODUCTION IN DOMESTIC ANIMALS
- Induction of Synthetic Polyploids and Assessment of Genomic Stability in Lippia alba
- (2020) Sirlei Aparecida Julião et al. Frontiers in Plant Science
- Cancer Stem Cells as a Potential Target to Overcome Multidrug Resistance
- (2020) Yena Cho et al. Frontiers in Oncology
- The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization
- (2020) Kang Du et al. Nature Ecology & Evolution
- Cardiomyocytes in congenital heart disease: Overcoming cytokinesis failure in tetralogy of Fallot
- (2020) Olaf Bergmann JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
- Polyploidy: A Biological Force From Cells to Ecosystems
- (2020) Donald T. Fox et al. TRENDS IN CELL BIOLOGY
- Integrating mathematical modeling with high throughput imaging explains how polyploid populations behave in nutrient-sparse environments
- (2020) Gregory J. Kimmel et al. CANCER RESEARCH
- Towards understanding the origin of animal development
- (2020) Iñaki Ruiz-Trillo et al. DEVELOPMENT
- Identifying key questions in the ecology and evolution of cancer
- (2020) Antoine M. Dujon et al. Evolutionary Applications
- Phylostratic Shift of Whole-Genome Duplications in Normal Mammalian Tissues towards Unicellularity Is Driven by Developmental Bivalent Genes and Reveals a Link to Cancer
- (2020) Olga V. Anatskaya et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Paradoxes of cancer: Survival at the brink
- (2020) Jekaterina Erenpreisa et al. SEMINARS IN CANCER BIOLOGY
- Therapy-induced polyploidization and senescence: Coincidence or interconnection?
- (2020) Ewa Sikora et al. SEMINARS IN CANCER BIOLOGY
- Wound-induced polyploidization is dependent on Integrin-Yki signaling
- (2020) Rose Besen-McNally et al. Biology Open
- The Cancer Aneuploidy Paradox: In the Light of Evolution
- (2019) Kristine Salmina et al. Genes
- Surviving Acute Organ Failure: Cell Polyploidization and Progenitor Proliferation
- (2019) Elena Lazzeri et al. TRENDS IN MOLECULAR MEDICINE
- Nuclear Scaling Is Coordinated among Individual Nuclei in Multinucleated Muscle Fibers
- (2019) Stefanie E. Windner et al. DEVELOPMENTAL CELL
- Histone stress: an unexplored source of chromosomal instability in cancer?
- (2019) Douglas Maya Miles et al. CURRENT GENETICS
- Evolutionary and developmental mismatches are consequences of adaptive developmental plasticity in humans and have implications for later disease risk
- (2019) Peter D. Gluckman et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Evolutionary framework of the human interactome: Unicellular and multicellular giant clusters
- (2019) A.E. Vinogradov et al. BIOSYSTEMS
- Age Mosaicism across Multiple Scales in Adult Tissues
- (2019) Rafael Arrojo e Drigo et al. Cell Metabolism
- Genome-Wide Association Study for Multiple Biotic Stress Resistance in Synthetic Hexaploid Wheat
- (2019) Madhav Bhatta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetic responses and the developmental origins of health and disease
- (2019) Dipali Goyal et al. JOURNAL OF ENDOCRINOLOGY
- Using digital organisms to study the evolutionary consequences of whole genome duplication and polyploidy
- (2019) Yao Yao et al. PLoS One
- Microglial memory of early life stress and inflammation: Susceptibility to neurodegeneration in adulthood
- (2019) Paula Desplats et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- OHNOLOGS v2: a comprehensive resource for the genes retained from whole genome duplication in vertebrates
- (2019) Param Priya Singh et al. NUCLEIC ACIDS RESEARCH
- The DisGeNET knowledge platform for disease genomics: 2019 update
- (2019) Janet Piñero et al. NUCLEIC ACIDS RESEARCH
- Residual Diploidy in Polyploid Tissues: A Cellular State with Enhanced Proliferative Capacity for Tissue Regeneration?
- (2019) Michaela Patterson et al. STEM CELLS AND DEVELOPMENT
- Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency
- (2019) Peiheng Gan et al. PLoS Genetics
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- (2019) Elisavet Fotiou et al. Circulation-Genomic and Precision Medicine
- aCLS cancers: Genomic and epigenetic changes transform the cell of origin of cancer into a tumorigenic pathogen of unicellular organization and lifestyle
- (2019) Vladimir F. Niculescu GENE
- Editorial: A New Bright Era for Evolutionary Medicine
- (2019) Konstantinos Voskarides JOURNAL OF MOLECULAR EVOLUTION
- Polyploidy and nuclear phenotype characteristics of cardiomyocytes from diabetic adult and normoglycemic aged mice
- (2018) Isabela S. Silva et al. ACTA HISTOCHEMICA
- How the evolution of multicellularity set the stage for cancer
- (2018) Anna S Trigos et al. BRITISH JOURNAL OF CANCER
- Polyploidy in tissue homeostasis and regeneration
- (2018) Jan Inge Øvrebø et al. DEVELOPMENT
- The Polyploid State Plays a Tumor-Suppressive Role in the Liver
- (2018) Shuyuan Zhang et al. DEVELOPMENTAL CELL
- Gene Golden Age paradox and its partial solution
- (2018) A.E. Vinogradov et al. GENOMICS
- Natural killer cell activity irreversibly decreases after Cryptosporidium gastroenteritis in neonatal mice
- (2018) N. A. Filatova et al. PARASITE IMMUNOLOGY
- The Dualistic Origin of Human Tumors
- (2018) Jinsong Liu SEMINARS IN CANCER BIOLOGY
- Endoreplication: The Good, the Bad, and the Ugly
- (2018) Zhiqiang Shu et al. TRENDS IN CELL BIOLOGY
- AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors
- (2018) Hui Hu et al. NUCLEIC ACIDS RESEARCH
- Cis -trans controls and regulatory novelty accompanying allopolyploidization
- (2018) Guanjing Hu et al. NEW PHYTOLOGIST
- Solving the Polyploid Mystery in Health and Disease
- (2018) K.J. Gjelsvik et al. TRENDS IN GENETICS
- Evolution of the Largest Mammalian Genome
- (2017) Ben J. Evans et al. Genome Biology and Evolution
- Evolution of the duplicated intracellular lipid-binding protein genes of teleost fishes
- (2017) Ananda B. Venkatachalam et al. MOLECULAR GENETICS AND GENOMICS
- 3D structures of individual mammalian genomes studied by single-cell Hi-C
- (2017) Tim J. Stevens et al. NATURE
- Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration
- (2017) Michaela Patterson et al. NATURE GENETICS
- The evolutionary significance of polyploidy
- (2017) Yves Van de Peer et al. NATURE REVIEWS GENETICS
- Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors
- (2017) Anna S. Trigos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular signatures of longevity: Insights from cross-species comparative studies
- (2017) Siming Ma et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Transcriptome analysis of neo-tetraploid rice reveals specific differential gene expressions associated with fertility and heterosis
- (2017) Haibin Guo et al. Scientific Reports
- Polyploidy and community structure
- (2017) Jörg Soppa Nature Microbiology
- Epigenetic response to environmental stress: Assembly of BRG1–G9a/GLP–DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts
- (2016) Pei Han et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas
- (2016) Laura Herrtwich et al. CELL
- Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication
- (2016) Luis M. Corrochano et al. CURRENT BIOLOGY
- Tetraploidy enhances the ability to exclude chloride from leaves in carrizo citrange seedlings
- (2016) M. Ruiz et al. JOURNAL OF PLANT PHYSIOLOGY
- Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53
- (2016) Tamara A. Potapova et al. MOLECULAR BIOLOGY OF THE CELL
- An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research
- (2016) Franck Court et al. Oncotarget
- Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signature
- (2016) Alejandro Vazquez-Martin et al. Oncotarget
- The Phenotypic Plasticity of Duplicated Genes in Saccharomyces cerevisiae and the Origin of Adaptations
- (2016) Florian Mattenberger et al. G3-Genes Genomes Genetics
- Endopolyploidy as a potential driver of animal ecology and evolution
- (2015) Maurine Neiman et al. BIOLOGICAL REVIEWS
- Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells
- (2015) Jop Kind et al. CELL
- Accelerated pathway evolution in mouse-like rodents involves cell cycle control
- (2015) Alexander E. Vinogradov MAMMALIAN GENOME
- On the relative abundance of autopolyploids and allopolyploids
- (2015) Michael S. Barker et al. NEW PHYTOLOGIST
- The ancestral gene repertoire of animal stem cells
- (2015) Alexandre Alié et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapid genome reshaping by multiple-gene loss after whole-genome duplication in teleost fish suggested by mathematical modeling
- (2015) Jun Inoue et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autotetraploid rice methylome analysis reveals methylation variation of transposable elements and their effects on gene expression
- (2015) Jie Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Genetics, Morphology, Advertisement Calls, and Historical Records Distinguish Six New Polyploid Species of African Clawed Frog (Xenopus, Pipidae) from West and Central Africa
- (2015) Ben J. Evans et al. PLoS One
- The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response
- (2014) Bao N. Puente et al. CELL
- Cellular Senescence in Ageing, Age-Related Disease and Longevity
- (2014) Ewa Sikora et al. Current Vascular Pharmacology
- A neonatal blueprint for cardiac regeneration
- (2014) Enzo R. Porrello et al. Stem Cell Research
- Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease
- (2014) Ralf Gilsbach et al. Nature Communications
- Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation
- (2014) T Kuga et al. Oncogenesis
- Invasion and genome reproduction of the trophoblast cells of placenta junctional zone in the field vole,Microtus rossiaemeridionalis
- (2013) Tatiana G. Zybina et al. CELL BIOLOGY INTERNATIONAL
- Changes in the heart of neonatal rats after cryptosporidial gastroenteritis of different degrees of severity
- (2013) O. V. Anatskaya et al. JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY
- Cardiomyocyte proliferation contributes to heart growth in young humans
- (2013) Mariya Mollova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Watching the grin fade: Tracing the effects of polyploidy on different evolutionary time scales
- (2013) Dustin Mayfield-Jones et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Physiological significance of polyploidization in mammalian cells
- (2013) Shusil K. Pandit et al. TRENDS IN CELL BIOLOGY
- Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis
- (2012) Assaf Malik et al. BMC GENOMICS
- Polyploidy and chromatin remodeling in hepatocytes from insulin-dependent diabetic and normoglycemic aged mice
- (2012) Flávia G. Ghiraldini et al. CYTOMETRY PART A
- Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression
- (2012) Li Zheng et al. Nature Communications
- Child Health, Developmental Plasticity, and Epigenetic Programming
- (2011) Z. Hochberg et al. ENDOCRINE REVIEWS
- Spontaneous speciation by ploidy elevation: Laboratory synthesis of a new clonal vertebrate
- (2011) C. Moritz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cardiac remodelling as a result of pre-term birth: implications for future cardiovascular disease
- (2010) Jonathan G. Bensley et al. EUROPEAN HEART JOURNAL
- Somatic polyploidy promotes cell function under stress and energy depletion: evidence from tissue-specific mammal transcriptome
- (2010) Olga V. Anatskaya et al. FUNCTIONAL & INTEGRATIVE GENOMICS
- Human transcriptome nexuses: Basic-eukaryotic and metazoan
- (2010) Alexander E. Vinogradov GENOMICS
- A study on QT interval in patients affected with inflammatory bowel disease without cardiac involvement
- (2010) Mario Curione et al. Internal and Emergency Medicine
- Loss of protein interactions and regulatory divergence in yeast whole-genome duplicates
- (2009) Alexander E. Vinogradov et al. GENOMICS
- Neonatal cardiomyocyte ploidy reveals critical windows of heart development
- (2009) Olga V. Anatskaya et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Global Versus Local Centrality in Evolution of Yeast Protein Network
- (2009) Alexander E. Vinogradov JOURNAL OF MOLECULAR EVOLUTION
- Developmental Origins of Adult Disease
- (2009) Rebecca A. Simmons PEDIATRIC CLINICS OF NORTH AMERICA
- Evolution of the human lifespan and diseases of aging: Roles of infection, inflammation, and nutrition
- (2009) C. E. Finch PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Two germ cell lineages with genomes of different species in one and the same animal
- (2008) A. E. VINOGRADOV et al. HEREDITAS
- Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome
- (2008) Kjersti M Aagaard-Tillery et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
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