CELL CYCLE STRESS IN NORMAL HUMAN CELLS: A ROUTE TO “FIRST CELLS” (WITH/WITHOUT FITNESS GAIN) AND CANCER-LIKE CELL-SHAPE CHANGES

Knocking out barriers to engineered cell activity

(2020) Jennifer R. Hamilton et al.   SCIENCE

When Three Isn't a Crowd: A Digyny Concept for Treatment-Resistant, Near-Triploid Human Cancers

(2019) Salmina et al.   Genes

Is genome-guided cancer treatment hyped?

(2018) Jocelyn Kaiser   SCIENCE

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

(2017) Xiaoyang Lan et al.   NATURE

Genes, environment, and “bad luck”

(2017) Martin A. Nowak et al.   SCIENCE

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

(2017) Cristian Tomasetti et al.   SCIENCE

Morphological and Functional Characteristic of Senescent Cancer Cells

(2016) Ewa Sikora et al.   CURRENT DRUG TARGETS

Evaluating the evaluation of cancer driver genes

(2016) Collin J. Tokheim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drugging DNA repair

(2016) Stephen P. Jackson et al.   SCIENCE

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

(2016) D. R. Pattabiraman et al.   SCIENCE

Sister chromatid decatenation: bridging the gaps in our knowledge

(2015) Ronan Broderick et al.   CELL CYCLE

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

NIH opens precision medicine study to nation

(2015) J. Kaiser   SCIENCE

Realizing the Promise

(2015) K. L. Mueller   SCIENCE

A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype

(2015) Verena Rohnalter et al.   Oncotarget

Distinct Patterns of Structural and Numerical Chromosomal Instability Characterize Sporadic Ovarian Cancer

(2015) Jane Bayani et al.   NEOPLASIA

Coming Full Circle—From Endless Complexity to Simplicity and Back Again

(2014) Robert A. Weinberg   CELL

Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations

(2014) James C Garbe et al.   CELL CYCLE

The aging of the 2000 and 2011 Hallmarks of Cancer reviews: A critique

(2013) Carlos Sonnenschein et al.   JOURNAL OF BIOSCIENCES

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells

(2013) Lauren M. Zasadil et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Telomere-Driven Tetraploidization Occurs in Human Cells Undergoing Crisis and Promotes Transformation of Mouse Cells

(2012) Teresa Davoli et al.   CANCER CELL

Polyploidy road to therapy-induced cellular senescence and escape

(2012) Qin Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia

(2012) S Safavi et al.   LEUKEMIA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Genome reversion process of endopolyploidy confers chromosome instability on the descendent diploid cells

(2011) Kirsten H. Walen   CELL BIOLOGY INTERNATIONAL

Polyploid tumour cells elicit paradiploid progeny through depolyploidizing divisions and regulated autophagic degradation

(2011) Jekaterina Erenpreisa et al.   CELL BIOLOGY INTERNATIONAL

Is carcinogenesis a form of speciation?

(2011) Peter Duesberg et al.   CELL CYCLE

The aneuploidy paradox: costs and benefits of an incorrect karyotype

(2011) Jason M. Sheltzer et al.   TRENDS IN GENETICS

Mitosis is not the only distributor of mutated cells: non-mitotic endopolyploid cells produce reproductive genome-reduced cells

(2010) Kirsten H Walen   CELL BIOLOGY INTERNATIONAL

Accumulation of driver and passenger mutations during tumor progression

(2010) I. Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fission Yeast Cells Undergo Nuclear Division in the Absence of Spindle Microtubules

(2010) Stefania Castagnetti et al.   PLOS BIOLOGY

Epithelial-Mesenchymal Transition

(2009) Michael W. Klymkowsky et al.   AMERICAN JOURNAL OF PATHOLOGY

THE ANIMAL WITHIN: CARCINOGENESIS AND THE CLONAL EVOLUTION OF CANCER CELLS ARE SPECIATION EVENTS SENSU STRICTO

(2009) Mark D. Vincent   EVOLUTION

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

(2009) R J DeBerardinis et al.   ONCOGENE

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

(2008) Pierre-Emmanuel Puig et al.   CELL BIOLOGY INTERNATIONAL