Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation

Agmatine Mitigates Inflammation-Related Oxidative Stress in BV-2 Cells by Inducing a Pre-Adaptive Response

(2022) Katarina Milosevic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phytochemicals as regulators of microglia/macrophages activation in cerebral ischemia

(2021) Lalita Subedi et al.   PHARMACOLOGICAL RESEARCH

Epigallocatechin-3-Gallate-Loaded Liposomes Favor Anti-Inflammation of Microglia Cells and Promote Neuroprotection

(2021) Chun-Yuan Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ginsenoside Rk1 protects human melanocytes from H2O2‑induced oxidative injury via regulation of the PI3K/AKT/Nrf2/HO‑1 pathway

(2021) Jian Xiong et al.   Molecular Medicine Reports

ω-3 DPA Protected Neurons from Neuroinflammation by Balancing Microglia M1/M2 Polarizations through Inhibiting NF-κB/MAPK p38 Signaling and Activating Neuron-BDNF-PI3K/AKT Pathways

(2021) Baiping Liu et al.   Marine Drugs

Neuroinflammatory Triangle Presenting Novel Pharmacological Targets for Ischemic Brain Injury

(2021) Zaib A. Shaheryar et al.   Frontiers in Immunology

Beneficial Properties of Green Tea Catechins

(2020) Claudia Musial et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Catechins reduce inflammation in lipopolysaccharide‐stimulated dental pulp cells by inhibiting activation of the NF‐κB pathway

(2020) Fang Wang et al.   ORAL DISEASES

Propofol Attenuates Hypoxia-Induced Inflammation in BV2 Microglia by Inhibiting Oxidative Stress and NF-κB/Hif-1α Signaling

(2020) Xiaowei Peng et al.   Biomed Research International

Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation

(2019) Lalita Subedi et al.   Cells

Early Pro-inflammatory Microglia Activation After Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats

(2019) Meray Serdar et al.   Frontiers in Cellular Neuroscience

STAT1 drives M1 microglia activation and neuroinflammation under hypoxia

(2019) Elena Butturini et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Function of Green Tea Catechins in the Brain: Epigallocatechin Gallate and its Metabolites

(2019) Monira Pervin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

(2019) Annamaria Vezzani et al.   Nature Reviews Neurology

Epigallocatechin‐3‐Gallate Attenuates Microglial Inflammation and Neurotoxicity by Suppressing the Activation of Canonical and Noncanonical Inflammasome via TLR4/NF‐κB Pathway

(2019) Xin Zhong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Green Tea Polyphenol (−)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice

(2019) Limin Mao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells

(2019) Shan Han et al.   Scientific Reports

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

(-)-Epigallocatechin-3-gallate modulates peripheral immunity in the MPTP-induced mouse model of Parkinson's disease

(2018) Tingting Zhou et al.   Molecular Medicine Reports

Epigallocatechin-3-Gallate Ameliorates Glucocorticoid-Induced Osteoporosis of Rats in Vivo and in Vitro

(2018) Shengye Liu et al.   Frontiers in Pharmacology

Understanding the Role of Hypoxia Inducible Factor During Neurodegeneration for New Therapeutics Opportunities

(2018) Amalia Merelli et al.   Current Neuropharmacology

Tea Polyphenols in Promotion of Human Health

(2018) Naghma Khan et al.   Nutrients

Carvedilol abrogates hypoxia-induced oxidative stress and neuroinflammation in microglial BV2 cells

(2017) Xiujuan Gao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes

(2017) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diallyl Disulfide Suppresses the Inflammation and Apoptosis Resistance Induced by DCA Through ROS and the NF-κB Signaling Pathway in Human Barrett’s Epithelial Cells

(2017) Cheng Feng et al.   INFLAMMATION

Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor

(2017) Xue Yan et al.   Scientific Reports

Coenzyme Q 0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of LPS-induced inflammation and redox imbalance: Evidence from in vitro and in vivo studies

(2016) Hsin-Ling Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Hydrangenol inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglial cells by suppressing the NF-κB pathway and activating the Nrf2-mediated HO-1 pathway

(2016) Hee-Ju Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-κB signaling pathway in mice

(2016) Kyung-Joo Seong et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway

(2016) Yalong Dang et al.   Drug Design Development and Therapy

Targeting Hypoxia-Inducible Factor 1 to Stimulate Tissue Vascularization

(2015) Gregg L. Semenza   JOURNAL OF INVESTIGATIVE MEDICINE

Neuroinflammation: Ways in Which the Immune System Affects the Brain

(2015) Richard M. Ransohoff et al.   Neurotherapeutics

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Neurological deficits caused by tissue hypoxia in neuroinflammatory disease

(2013) Andrew L. Davies et al.   ANNALS OF NEUROLOGY

Defective HIF Signaling Pathway and Brain Response to Hypoxia in Neurodegenerative Diseases: Not an “Iffy” Question!

(2013) Sónia C. Correia et al.   CURRENT PHARMACEUTICAL DESIGN

Death by a Thousand Cuts in Alzheimer’s Disease: Hypoxia—The Prodrome

(2013) Mak Adam Daulatzai   NEUROTOXICITY RESEARCH

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo

(2012) Yu-Ting Cheng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

(2011) Sarah R. Walmsley et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

N-acetyl-L-cysteine counteracts oxidative stress and prevents H2O2 induced germ cell apoptosis through down-regulation of caspase-9 and JNK/c-Jun

(2010) Ankur Maheshwari et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

NFκB: a promising target for natural products in cancer chemoprevention

(2010) Suaib Luqman et al.   PHYTOTHERAPY RESEARCH

Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway

(2009) Nobuko Koshikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Green Tea Epigallocatechin 3-Gallate Accumulates in Mitochondria and Displays a Selective Antiapoptotic Effect Against Inducers of Mitochondrial Oxidative Stress in Neurons

(2008) Emily K. Schroeder et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidants and Neuroprotection in the Adult and Developing Central Nervous System

(2008) Charanjit Kaur et al.   CURRENT MEDICINAL CHEMISTRY