Neuroinflammation: Ways in Which the Immune System Affects the Brain

Epileptogenic effects of NMDAR antibodies in a passive transfer mouse model

(2015) Sukhvir Wright et al.   BRAIN

Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages

(2015) Dorothy P. Schafer et al.   IMMUNITY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis

(2014) Emilia H. Moscato et al.   ANNALS OF NEUROLOGY

Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes

(2014) Alexander Carvajal-González et al.   BRAIN

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN

Leukocyte recruitment in inflammation: basic concepts and new mechanistic insights based on new models and microscopic imaging technologies

(2014) Marion Leick et al.   CELL AND TISSUE RESEARCH

T cells targeting a neuronal paraneoplastic antigen mediate tumor rejection and trigger CNS autoimmunity with humoral activation

(2014) Nathalie E. Blachère et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Maternal immune activation and abnormal brain development across CNS disorders

(2014) Irene Knuesel et al.   Nature Reviews Neurology

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype

(2013) Sarosh R. Irani et al.   BRAIN

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Role of emergent neural activity in visual map development

(2013) James B Ackman et al.   CURRENT OPINION IN NEUROBIOLOGY

Autoantibodies to Epilepsy-Related LGI1 in Limbic Encephalitis Neutralize LGI1-ADAM22 Interaction and Reduce Synaptic AMPA Receptors

(2013) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

(2013) Maarten J Titulaer et al.   LANCET NEUROLOGY

Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study

(2013) Sean J Pittock et al.   LANCET NEUROLOGY

N-methyl-D-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse

(2013) Yael Hacohen et al.   MOVEMENT DISORDERS

Layer V cortical neurons require microglial support for survival during postnatal development

(2013) Masaki Ueno et al.   NATURE NEUROSCIENCE

Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report

(2013) F. Leypoldt et al.   NEUROLOGY

Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement

(2013) Rita João Guerreiro et al.   JAMA Neurology

Cellular Immune Suppression in Paraneoplastic Neurologic Syndromes Targeting Intracellular Antigens

(2012) Dana Orange et al.   ARCHIVES OF NEUROLOGY

The Frequency of Autoimmune N-Methyl-D-Aspartate Receptor Encephalitis Surpasses That of Individual Viral Etiologies in Young Individuals Enrolled in the California Encephalitis Project

(2012) M. S. Gable et al.   CLINICAL INFECTIOUS DISEASES

Secretory products of multiple sclerosis B cells are cytotoxic to oligodendroglia in vitro

(2012) Robert P. Lisak et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Treatment of neuromyelitis optica: Review and recommendations

(2012) Dorlan J. Kimbrough et al.   Multiple Sclerosis and Related Disorders

Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis

(2011) Laura Lovato et al.   BRAIN

Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis

(2011) Owain W. Howell et al.   BRAIN

Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin

(2011) Birgit Obermeier et al.   JOURNAL OF NEUROIMMUNOLOGY

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial

(2011) Ludwig Kappos et al.   LANCET

Autoantibodies associated with diseases of the CNS: new developments and future challenges

(2011) Angela Vincent et al.   LANCET NEUROLOGY

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut

(2011) Jörg H. Fritz et al.   NATURE

Experience-Dependent Retinogeniculate Synapse Remodeling Is Abnormal in MeCP2-Deficient Mice

(2011) Joao Noutel et al.   NEURON

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis

(2010) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

Changes in B- and T-Lymphocyte and Chemokine Levels With Rituximab Treatment in Multiple Sclerosis

(2010) Laura Piccio et al.   ARCHIVES OF NEUROLOGY

N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

(2010) Sarosh R. Irani et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission

(2010) Tatjana Lalic et al.   EPILEPSIA

Anti-myelin antibodies modulate clinical expression of childhood multiple sclerosis

(2010) K.C. O'Connor et al.   JOURNAL OF NEUROIMMUNOLOGY

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

(2010) Josep Dalmau et al.   LANCET NEUROLOGY

Rituximab add-on therapy for breakthrough relapsing multiple sclerosis: A 52-week phase II trial

(2010) R. T. Naismith et al.   NEUROLOGY

Morphological and immunohistochemical characterization of paraneoplastic cerebellar degeneration associated with Yo antibodies

(2009) A. Storstein et al.   ACTA NEUROLOGICA SCANDINAVICA

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

(2009) Amit Bar-Or et al.   ANNALS OF NEUROLOGY

Helminth infections associated with multiple sclerosis induce regulatory B cells

(2008) Jorge Correale et al.   ANNALS OF NEUROLOGY

Rituximab in relapsing-remitting multiple sclerosis: A 72-week, open-label, phase I trial

(2008) Amit Bar-Or et al.   ANNALS OF NEUROLOGY

Mechanisms Underlying Development of Visual Maps and Receptive Fields

(2008) Andrew D. Huberman et al.   Annual Review of Neuroscience

Vision Triggers an Experience-Dependent Sensitive Period at the Retinogeniculate Synapse

(2008) B. M. Hooks et al.   JOURNAL OF NEUROSCIENCE

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

PROGRESSIVE ENCEPHALOMYELITIS, RIGIDITY, AND MYOCLONUS: A NOVEL GLYCINE RECEPTOR ANTIBODY

(2008) M. Hutchinson et al.   NEUROLOGY

Microglial clearance function in health and disease

(2008) I. Napoli et al.   NEUROSCIENCE

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE