ARTC2.2/P2RX7 Signaling during Cell Isolation Distorts Function and Quantification of Tissue-Resident CD8+ T Cell and Invariant NKT Subsets

Blocking the ART2.2/P2X7-system is essential to avoid a detrimental bias in functional CD4 T cell studies

(2018) Hristo Georgiev et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

(2018) Lalit K. Beura et al.   NATURE IMMUNOLOGY

The Elusive P2X7 Macropore

(2018) Francesco Di Virgilio et al.   TRENDS IN CELL BIOLOGY

In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells

(2018) Björn Rissiek et al.   Frontiers in Immunology

How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets

(2018) Haiguang Wang et al.   Frontiers in Immunology

Insights Into Mucosal-Associated Invariant T Cell Biology From Studies of Invariant Natural Killer T Cells

(2018) Lucy C. Garner et al.   Frontiers in Immunology

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells

(2018) Henrique Borges da Silva et al.   NATURE

CCR7 defines a precursor for murine iNKT cells in thymus and periphery

(2018) Haiguang Wang et al.   eLife

A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

(2018) Marion Salou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The P2X7 Receptor in Infection and Inflammation

(2017) Francesco Di Virgilio et al.   IMMUNITY

P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria

(2017) Érika Machado de Salles et al.   PLoS Pathogens

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

(2016) Daniel Fernandez-Ruiz et al.   IMMUNITY

IL-4 sensitivity shapes the peripheral CD8 + T cell pool and response to infection

(2016) Kristin R. Renkema et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Contraction of intestinal effector T cells by retinoic acid-induced purinergic receptor P2X7

(2016) S Hashimoto-Hill et al.   Mucosal Immunology

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

(2016) Se Jin Im et al.   NATURE

How MAIT cells get their start

(2016) Haiguang Wang et al.   NATURE IMMUNOLOGY

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

(2016) Hui-Fern Koay et al.   NATURE IMMUNOLOGY

Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation

(2016) W. Danquah et al.   Science Translational Medicine

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Tissue-Specific Distribution of iNKT Cells Impacts Their Cytokine Response

(2015) You Jeong Lee et al.   IMMUNITY

P2X7 on Mouse T Cells: One Channel, Many Functions

(2015) Björn Rissiek et al.   Frontiers in Immunology

ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism

(2014) Michele Proietti et al.   IMMUNITY

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

High Sensitivity of Intestinal CD8+ T Cells to Nucleotides Indicates P2X7 as a Regulator for Intestinal T Cell Responses

(2014) K. Heiss et al.   JOURNAL OF IMMUNOLOGY

Intravascular staining for discrimination of vascular and tissue leukocytes

(2014) Kristin G Anderson et al.   Nature Protocols

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

Technical Advance: A new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells

(2013) Björn Rissiek et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

(2011) U. Schenk et al.   Science Signaling

NAD+ and ATP Released from Injured Cells Induce P2X7-Dependent Shedding of CD62L and Externalization of Phosphatidylserine by Murine T Cells

(2009) F. Scheuplein et al.   JOURNAL OF IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Purinergic Control of T Cell Activation by ATP Released Through Pannexin-1 Hemichannels

(2008) U. Schenk et al.   Science Signaling

ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site

(2007) Sahil Adriouch et al.   FASEB JOURNAL