Acute lung inflammation induced by zinc oxide nanoparticles: Evolution and intervention via NRF2 activator

From Flies to Men: ROS and the NADPH Oxidase in Phagocytes

(2021) Zohreh Mansoori Moghadam et al.   Frontiers in Cell and Developmental Biology

Assessment of respiratory and systemic toxicity of Benzalkonium chloride following a 14-day inhalation study in rats

(2020) Hye-Yeon Choi et al.   Particle and Fibre Toxicology

Fast and Robust Proteome Screening Platform Identifies Neutrophil Extracellular Trap Formation in the Lung in Response to Cobalt Ferrite Nanoparticles

(2020) Anja M. Billing et al.   ACS Nano

Health effects after inhalation of micro- and nano-sized zinc oxide particles in human volunteers

(2020) Christian Monsé et al.   ARCHIVES OF TOXICOLOGY

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response

(2019) Ryuichi Nagashima et al.   JOURNAL OF IMMUNOLOGY

Heterozygous Disruption of Beclin 1 Alleviates Zinc Oxide Nanoparticles-Induced Disturbance of Cholesterol Biosynthesis in Mouse Liver

(2019) Xuemei Liu et al.   International Journal of Nanomedicine

Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles

(2019) Radwa Sehsah et al.   Particle and Fibre Toxicology

Effect of Intratracheal Instillation of ZnO Nanoparticles on Acute Lung Inflammation Induced by Lipopolysaccharides in Mice

(2019) Ping Wang et al.   TOXICOLOGICAL SCIENCES

Airway inflammation after inhalation of nano-sized zinc oxide particles in human volunteers

(2019) Christian Monsé et al.   BMC Pulmonary Medicine

Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression

(2019) Peng Xue et al.   Redox Biology

Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling

(2018) Jia Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Concentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteers

(2018) Christian Monsé et al.   Particle and Fibre Toxicology

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Autophagy-dependent release of zinc ions is critical for acute lung injury triggered by zinc oxide nanoparticles

(2018) Xuejun Jiang et al.   Nanotoxicology

Pulmonary pathobiology induced by zinc oxide nanoparticles in mice: A 24-hour and 28-day follow-up study

(2017) Hsiao-Chi Chuang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy

(2017) Dongwei Xu et al.   Cell Death & Disease

Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells

(2017) Jun Zhang et al.   Cell Death & Disease

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Silver nanoparticles activate endoplasmic reticulum stress signaling pathway in cell and mouse models: The role in toxicity evaluation

(2015) Lingling Huo et al.   BIOMATERIALS

Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories

(2015) Nicklas Raun Jacobsen et al.   FOOD AND CHEMICAL TOXICOLOGY

The protective effect of CDDO-Me on lipopolysaccharide-induced acute lung injury in mice

(2015) Tong Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles

(2014) Nagarjun V Konduru et al.   Particle and Fibre Toxicology

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

(2014) Anne Cleasby et al.   PLoS One

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

The mercurial nature of neutrophils: still an enigma in ARDS?

(2013) Andrew E. Williams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review

(2013) Olesja Bondarenko et al.   ARCHIVES OF TOXICOLOGY

The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia–reperfusion injury in mice

(2013) Manchang Liu et al.   KIDNEY INTERNATIONAL

The Triterpenoid CDDO-Me Inhibits Bleomycin-Induced Lung Inflammation and Fibrosis

(2013) Ajit A. Kulkarni et al.   PLoS One

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Conditional Deletion ofNrf2in Airway Epithelium Exacerbates Acute Lung Injury and Impairs the Resolution of Inflammation

(2011) Narsa M. Reddy et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

The Triterpenoid CDDO-Imidazolide Confers Potent Protection against Hyperoxic Acute Lung Injury in Mice

(2009) Narsa M. Reddy et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Priming of the neutrophil NADPH oxidase activation: role of p47phox phosphorylation and NOX2 mobilization to the plasma membrane

(2008) Jamel El-Benna et al.   Seminars in Immunopathology