The mercurial nature of neutrophils: still an enigma in ARDS?

Infiltrated Neutrophils Acquire Novel Chemokine Receptor Expression and Chemokine Responsiveness in Chronic Inflammatory Lung Diseases

(2014) D. Hartl et al.   JOURNAL OF IMMUNOLOGY

The Role of MIP-1  in the Development of Systemic Inflammatory Response and Organ Injury following Trauma Hemorrhage

(2014) C.-H. Hsieh et al.   JOURNAL OF IMMUNOLOGY

A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation

(2014) A. Gaggar et al.   JOURNAL OF IMMUNOLOGY

Chlorine gas exposure increases susceptibility to invasive lung fungal infection

(2013) Melissa A. Gessner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury

(2013) Rachel L. Zemans et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

HMGB1 promotes neutrophil extracellular trap formation through interactions with Toll-like receptor 4

(2013) Jean-Marc Tadie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Proteinase-Activated Receptor-1, CCL2 and CCL7 Regulate Acute Neutrophilic Lung Inflammation

(2013) Paul F Mercer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Prehospital use of inhaled steroids and incidence of acute lung injury among patients at risk

(2013) Emir Festic et al.   JOURNAL OF CRITICAL CARE

NET balancing: a problem in inflammatory lung diseases

(2013) Olivia Z. Cheng et al.   Frontiers in Immunology

Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growth

(2012) Anne Hilgendorff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury

(2012) Jiurong Liang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury

(2012) Jochen Grommes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin

(2012) Akihiko Ichikawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

(2012) G. M. Thomas et al.   BLOOD

VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue

(2012) G. Christoffersson et al.   BLOOD

The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material

(2012) Niall D. Ferguson et al.   INTENSIVE CARE MEDICINE

Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

(2012) Junjie Mei et al.   JOURNAL OF CLINICAL INVESTIGATION

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

In Vivo Processing of CXCL5 (LIX) by Matrix Metalloproteinase (MMP)-2 and MMP-9 Promotes Early Neutrophil Recruitment in IL-1 -Induced Peritonitis

(2012) J. Song et al.   JOURNAL OF IMMUNOLOGY

Neutrophil-Mediated Inhibition of Proinflammatory Cytokine Responses

(2012) M. S. Gresnigt et al.   JOURNAL OF IMMUNOLOGY

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Intrapulmonary Administration of Leukotriene B4 Augments Neutrophil Accumulation and Responses in the Lung to Klebsiella Infection in CXCL1 Knockout Mice

(2012) S. Batra et al.   JOURNAL OF IMMUNOLOGY

Human suppressive neutrophils CD16bright /CD62Ldim exhibit decreased adhesion

(2012) Vera M. Kamp et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CXCR2 in Acute Lung Injury

(2012) F. M. Konrad et al.   MEDIATORS OF INFLAMMATION

Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity

(2012) M. Beyrau et al.   Open Biology

Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis

(2011) Teluguakula Narasaraju et al.   AMERICAN JOURNAL OF PATHOLOGY

SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans

(2011) Aili L. Lazaar et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury

(2011) Mitsuhiro Yamada et al.   Cellular & Molecular Immunology

Targeting of a common receptor shared by CXCL8 and N-Ac-PGP as a therapeutic strategy to alleviate chronic neutrophilic lung diseases

(2011) Robert J. Snelgrove   EUROPEAN JOURNAL OF PHARMACOLOGY

Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice

(2011) Naoya Fujino et al.   EXPERIMENTAL LUNG RESEARCH

Monocyte Chemoattractant Protein 1 Regulates Pulmonary Host Defense via Neutrophil Recruitment during Escherichia coli Infection

(2011) Gayathriy Balamayooran et al.   INFECTION AND IMMUNITY

Activation of endothelial TLR2 by bacterial lipoprotein upregulates proteins specific for the neutrophil response

(2011) Kevin Wilhelmsen et al.   Innate Immunity

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate Immune Collectin Surfactant Protein D Simultaneously Binds Both Neutrophil Extracellular Traps and Carbohydrate Ligands and Promotes Bacterial Trapping

(2011) D. N. Douda et al.   JOURNAL OF IMMUNOLOGY

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(2011) Jochen Grommes et al.   MOLECULAR MEDICINE

The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

(2011) Abigail Woodfin et al.   NATURE IMMUNOLOGY

A Self-Propagating Matrix Metalloprotease-9 (MMP-9) Dependent Cycle of Chronic Neutrophilic Inflammation

(2011) Xin Xu et al.   PLoS One

Neutrophil transmigration triggers repair of the lung epithelium via  -catenin signaling

(2011) R. L. Zemans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial repair mechanisms in the lung

(2010) Lynn M. Crosby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Neutrophil α-Defensins Cause Lung Injury by Disrupting the Capillary–Epithelial Barrier

(2010) Khalil Bdeir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neutrophils are significant producers of IL-10 during sepsis

(2010) Kevin R. Kasten et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Does activation of the FcγRIIa play a role in the pathogenesis of the acute lung injury/acute respiratory distress syndrome?

(2010) Rafal Fudala et al.   CLINICAL SCIENCE

Prediction of outcome in patients with acute respiratory distress syndrome by bronchoalveolar lavage inflammatory mediators

(2010) Wei-Chieh Lin et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

CXCL5 Regulates Chemokine Scavenging and Pulmonary Host Defense to Bacterial Infection

(2010) Junjie Mei et al.   IMMUNITY

Importance of CXC Chemokine Receptor 2 in Alveolar Neutrophil and Exudate Macrophage Recruitment in Response to Pneumococcal Lung Infection

(2010) W. Herbold et al.   INFECTION AND IMMUNITY

Effect of Neutrophil Elastase Inhibitor (Sivelestat Sodium) in the Treatment of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS): A Systematic Review and Meta-Analysis

(2010) Kentaro Iwata et al.   INTERNAL MEDICINE

Pulmonary epithelial CCR3 promotes LPS-induced lung inflammation by mediating release of IL-8

(2010) Bo Li et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

(2010) Kyle J. Eash et al.   JOURNAL OF CLINICAL INVESTIGATION

CXCL1 Regulates Pulmonary Host Defense to Klebsiella Infection via CXCL2, CXCL5, NF- B, and MAPKs

(2010) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia

(2010) Janesh Pillay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Roles of CC chemokine receptors (CCRs) on lipopolysaccharide-induced acute lung injury

(2010) Dong Yang et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

NEUTROPHIL PARALYSIS IN SEPSIS

(2010) José C. Alves-Filho et al.   SHOCK

Neutrophil Extracellular Traps: How to Generate and Visualize Them

(2010) Volker Brinkmann et al.   Jove-Journal of Visualized Experiments

Neutrophil-mediated lung permeability and host defense proteins

(2009) Stephen P. Kantrow et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines

(2009) K. Hayashida et al.   BLOOD

DARC on RBC limits lung injury by balancing compartmental distribution of CXC chemokines

(2009) Jörg Reutershan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects

(2009) O. Holz et al.   EUROPEAN RESPIRATORY JOURNAL

Humanized monoclonal antibody against the chemokine CXCL-8 (IL-8) effectively prevents acute lung injury

(2009) ZhiYao Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Neutrophil Elastase Is Needed for Neutrophil Emigration into Lungs in Ventilator-Induced Lung Injury

(2008) A. Murat Kaynar et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Anti-Chemokine Autoantibody:Chemokine Immune Complexes Activate Endothelial Cells via IgG Receptors

(2008) Agnieszka Krupa et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Transepithelial Migration of Neutrophils

(2008) Rachel L. Zemans et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice

(2008) A Zarbock et al.   BRITISH JOURNAL OF PHARMACOLOGY

Human neutrophils switch to an activated phenotype after homing to the lung irrespective of inflammatory disease

(2008) E. Fortunati et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neutrophil degranulation mediates severe lung damage triggered by streptococcal M1 protein

(2008) O. Soehnlein et al.   EUROPEAN RESPIRATORY JOURNAL

Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients

(2008) M. Swee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Low-dose dexamethasone alleviates lipopolysaccharide-induced acute lung injury in rats and upregulates pulmonary glucocorticoid receptors

(2008) Xiao-Qiu WANG et al.   RESPIROLOGY

CXCR3 and CCR5 Chemokines in Induced Sputum From Patients With COPD

(2007) Claudia Costa et al.   CHEST