Exercise-induced neuroprotection against cerebral ischemia/reperfusion injury is mediated via alleviating inflammasome-induced pyroptosis

High-Intensity Exercise Training Protects the Brain Against Autoimmune Neuroinflammation: Regulation of Microglial Redox and Pro-inflammatory Functions

(2021) Yifat Zaychik et al.   Frontiers in Cellular Neuroscience

Bone marrow mesenchymal stem cell-derived exosomes attenuate cerebral ischemia-reperfusion injury-induced neuroinflammation and pyroptosis by modulating microglia M1/M2 phenotypes

(2021) Xiaoli Liu et al.   EXPERIMENTAL NEUROLOGY

Relevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke

(2021) Qingxue Xu et al.   Journal of Neuroinflammation

Exercise training mitigates ER stress and UCP2 deficiency-associated coronary vascular dysfunction in atherosclerosis

(2021) Junyoung Hong et al.   Scientific Reports

New Approaches in Nanomedicine for Ischemic Stroke

(2021) Clara Correa-Paz et al.   Pharmaceutics

An Animal Trial on the Optimal Time and Intensity of Exercise after Stroke

(2020) Liying Zhang et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Effects of high-intensity interval training on adipose tissue lipolysis, inflammation, and metabolomics in aged rats

(2020) Lei Sun et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs

(2020) Débora da Luz Scheffer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

High-intensity interval training and moderate-intensity continuous training alleviate β-amyloid deposition by inhibiting NLRP3 inflammasome activation in APPswe/PS1dE9 mice

(2020) Fei Liang et al.   NEUROREPORT

Exercise training modulates the gut microbiota profile and impairs inflammatory signaling pathways in obese children

(2020) Rocío Quiroga et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Adiponectin peptide alleviates oxidative stress and NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/GSK-3β

(2020) Haixiao Liu et al.   EXPERIMENTAL NEUROLOGY

Inflammasome activation and regulation: toward a better understanding of complex mechanisms

(2020) Danping Zheng et al.   Cell Discovery

Kv1.3 channel blockade alleviates cerebral ischemia/reperfusion injury by reshaping M1/M2 phenotypes and compromising the activation of NLRP3 inflammasome in microglia

(2020) Dai-Chao Ma et al.   EXPERIMENTAL NEUROLOGY

The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice

(2020) Maximilian Franke et al.   BRAIN BEHAVIOR AND IMMUNITY

Aerobic Exercise Improves Synaptic-Related Proteins of Diabetic Rats by Inhibiting FOXO1/NF-κB/NLRP3 Inflammatory Signaling Pathway and Ameliorating PI3K/Akt Insulin Signaling Pathway

(2019) Qian Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Stroke in China: advances and challenges in epidemiology, prevention, and management

(2019) Simiao Wu et al.   LANCET NEUROLOGY

Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke

(2019) Natalia Kolosowska et al.   Neurotherapeutics

Physical Exercise Inhibits Inflammation and Microglial Activation

(2019) Mee-inta et al.   Cells

High Intensity Exercise for Walking Competency in Individuals with Stroke: A Systematic Review and Meta-Analysis

(2019) Lu Luo et al.   Journal of Stroke & Cerebrovascular Diseases

Effect of high-intensity exercise on cardiorespiratory fitness in stroke survivors: A systematic review and meta-analysis

(2019) Lu Luo et al.   Annals of Physical and Rehabilitation Medicine

Validity and Reliability of Neurological Scores in Mice Exposed to Middle Cerebral Artery Occlusion

(2019) Michael Bieber et al.   STROKE

Evidence that NLRC4 Inflammasome Mediates Apoptotic and Pyroptotic Microglial Death Following Ischemic Stroke

(2018) Luting Poh et al.   BRAIN BEHAVIOR AND IMMUNITY

Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury

(2018) Zhe Gong et al.   Journal of Neuroinflammation

Post-stroke Hemiplegic Gait: New Perspective and Insights

(2018) Sheng Li et al.   Frontiers in Physiology

High-Intensity Interval Training on Neuroplasticity, Balance between Brain-Derived Neurotrophic Factor and Precursor Brain-Derived Neurotrophic Factor in Poststroke Depression Rats

(2018) Lu Luo et al.   Journal of Stroke & Cerebrovascular Diseases

Experimental ischaemic stroke induces transient cardiac atrophy and dysfunction

(2018) Roland Veltkamp et al.   Journal of Cachexia Sarcopenia and Muscle

Does acupuncture ameliorate motor impairment after stroke? An assessment using the CatWalk gait system

(2017) Yan Cao et al.   NEUROCHEMISTRY INTERNATIONAL

High Intensity Interval Training for Maximizing Health Outcomes

(2017) Trine Karlsen et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Effects of High- Versus Moderate-Intensity Training on Neuroplasticity and Functional Recovery After Focal Ischemia

(2017) Caroline Pin-Barre et al.   STROKE

Gasdermins: Effectors of Pyroptosis

(2017) Stephen B. Kovacs et al.   TRENDS IN CELL BIOLOGY

Four birds with one stone? Reparative, neuroplastic, cardiorespiratory, and metabolic benefits of aerobic exercise poststroke

(2016) Michelle Ploughman et al.   CURRENT OPINION IN NEUROLOGY

The Immunomodulatory Effects of Physical Activity

(2016) Karsten Krüger et al.   CURRENT PHARMACEUTICAL DESIGN

Feasibility of Measuring Ventilatory Threshold in Adults With Stroke-Induced Hemiparesis: Implications for Exercise Prescription

(2015) Pamela Rogers Bosch et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial

(2015)   LANCET

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inflammasomes in the CNS

(2014) John G. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

Aerobic exercise effects on neuroprotection and brain repair following stroke: A systematic review and perspective

(2014) Mark W. Austin et al.   NEUROSCIENCE RESEARCH

The Effects of Poststroke Aerobic Exercise on Neuroplasticity: A Systematic Review of Animal and Clinical Studies

(2014) Michelle Ploughman et al.   Translational Stroke Research

Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage

(2013) Roslyn A. Taylor et al.   Clinical & Developmental Immunology

Meta-analysis of the Efficacy of Different Training Strategies in Animal Models of Ischemic Stroke

(2013) Antje Schmidt et al.   STROKE

Cardiorespiratory Fitness after Stroke: A Systematic Review

(2012) Alexandra C. Smith et al.   International Journal of Stroke

Physiological adaptations to low-volume, high-intensity interval training in health and disease

(2012) Martin J. Gibala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

(2011) Carlo Perego et al.   Journal of Neuroinflammation