Dietary phillygenin supplementation ameliorates aflatoxin B1-induced oxidative stress, inflammation, and apoptosis in chicken liver

Phillygenin inhibited LPS-induced RAW 264.7 cell inflammation by NF-κB pathway

(2021) Mengting Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Phillygenin protects against osteoarthritis by repressing inflammation via PI3K/Akt/NF-κB signaling: In vitro and vivo studies

(2021) Siqi Zhou et al.   Journal of Functional Foods

Phillygenin inhibits the inflammation and apoptosis of pulmonary epithelial cells by activating PPARγ signaling via downregulation of MMP8

(2021) Yufeng Lin et al.   Molecular Medicine Reports

Fungal Contamination and Aflatoxin B1 Detected in Hay for Dairy Cows in South Italy

(2021) Carlotta Ceniti et al.   Frontiers in Nutrition

Penthorum chinense Pursh Compound Ameliorates AFB1-Induced Oxidative Stress and Apoptosis via Modulation of Mitochondrial Pathways in Broiler Chicken Kidneys

(2021) Weilai Tao et al.   Frontiers in Veterinary Science

Self-Microemulsifying Drug Delivery System of Phillygenin: Formulation Development, Characterization and Pharmacokinetic Evaluation

(2020) Lingzhi Wang et al.   Pharmaceutics

Grape Seed Proanthocyanidin Extract Alleviates AflatoxinB1-Induced Immunotoxicity and Oxidative Stress via Modulation of NF-κB and Nrf2 Signaling Pathways in Broilers

(2019) Shahid Rajput et al.   Toxins

Lactobacillus bulgaricus or Lactobacillus rhamnosus Suppresses NF-κB Signaling Pathway and Protects against AFB1-Induced Hepatitis: A Novel Potential Preventive Strategy for Aflatoxicosis?

(2019) Yuanyuan Chen et al.   Toxins

Proanthocyanidins Alleviates AflatoxinB1-Induced Oxidative Stress and Apoptosis through Mitochondrial Pathway in the Bursa of Fabricius of Broilers

(2019) Shahid Rajput et al.   Toxins

Phillygenin exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes

(2019) Bingyuan Du et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Phillygenin, a lignan compound, inhibits hypertension by reducing PLCβ3-dependent Ca2+ oscillation

(2019) Wenjuan Liu et al.   Journal of Functional Foods

Phillygenin inhibits LPS-induced activation and inflammation of LX2 cells by TLR4/MyD88/NF-κB signaling pathway

(2019) Naihua Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phytochemistry, pharmacology, quality control and future research of Forsythia suspensa (Thunb.) Vahl: A review

(2018) Zhaoyi Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Roles of Reduced Nitric Oxide in Liver Cell Apoptosis Inhibition During Liver Damage

(2018) Ying-yi Wang et al.   ARCHIVES OF MEDICAL RESEARCH

Evaluation of the Pharmacokinetics and Hepatoprotective Effects of Phillygenin in Mouse

(2018) Wei Song et al.   Biomed Research International

Phillygenin attenuates inflammatory responses and influences glucose metabolic parameters by inhibiting Akt activity

(2017) Wenjuan Liu et al.   RSC Advances

Ameliorative Effects of Grape Seed Proanthocyanidin Extract on Growth Performance, Immune Function, Antioxidant Capacity, Biochemical Constituents, Liver Histopathology and Aflatoxin Residues in Broilers Exposed to Aflatoxin B1

(2017) Shahid Ali Rajput et al.   Toxins

Fisetin Modulates Antioxidant Enzymes and Inflammatory Factors to Inhibit Aflatoxin-B1 Induced Hepatocellular Carcinoma in Rats

(2016) Brajesh Kumar Maurya et al.   Oxidative Medicine and Cellular Longevity

Major apoptotic mechanisms and genes involved in apoptosis

(2016) Yağmur Kiraz et al.   TUMOR BIOLOGY

Forsythia suspensa Suppresses House Dust Mite Extract-Induced Atopic Dermatitis in NC/Nga Mice

(2016) Yoon-Young Sung et al.   PLoS One

Fungi and mycotoxins in stored foods

(2011) Atanda S. A   African Journal of Microbiology Research

Isoforsythiaside, an antioxidant and antibacterial phenylethanoid glycoside isolated from Forsythia suspensa

(2011) Huanhuan Qu et al.   BIOORGANIC CHEMISTRY

Detoxification as a treatment goal in hepatic failure

(2011) Ludwig Kramer et al.   LIVER INTERNATIONAL

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

(2010) Gerasimos P Sykiotis et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Global Burden of Aflatoxin-Induced Hepatocellular Carcinoma: A Risk Assessment

(2010) Yan Liu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice

(2010) K.-C. Choi et al.   FOOD AND CHEMICAL TOXICOLOGY

Aflatoxin B1 in poultry: Toxicology, metabolism and prevention

(2010) Sumit Rawal et al.   RESEARCH IN VETERINARY SCIENCE

Protective effects of Forsythia suspensa extract against oxidative stress induced by diquat in rats

(2009) T. Lu et al.   FOOD AND CHEMICAL TOXICOLOGY

In vitro antioxidant properties and in vivo lowering blood lipid of Forsythia suspense leaves

(2009) Wenyi Kang et al.   MEDICINAL CHEMISTRY RESEARCH

KEAP1 E3 Ligase-Mediated Downregulation of NF-κB Signaling by Targeting IKKβ

(2009) Dung-Fang Lee et al.   MOLECULAR CELL

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

(2008) Guang-Hui Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of Urtica dioica L. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats

(2008) Zabit Yener et al.   FOOD AND CHEMICAL TOXICOLOGY

Anti-inflammatory activity of phylligenin, a lignan from the fruits of Forsythia koreana, and its cellular mechanism of action

(2008) Hyun Lim et al.   JOURNAL OF ETHNOPHARMACOLOGY