ACE2, B0AT1, and SARS-CoV-2 spike protein: Structural and functional implications

Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system

(2021) Man Lung Yeung et al.   CELL

Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms

(2021) Alexandra E. Livanos et al.   GASTROENTEROLOGY

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

(2021) Meng Guo et al.   Nature Reviews Gastroenterology & Hepatology

An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants

(2021) Kui K. Chan et al.   Science Advances

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

(2021) Renhong Yan et al.   CELL RESEARCH

Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2

(2021) Renhong Yan et al.   CELL RESEARCH

Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells

(2021) Malte Lehmann et al.   Mucosal Immunology

Mechanisms of SARS-CoV-2 entry into cells

(2021) Cody B. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19

(2020) Y Song et al.   GUT

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2

(2020) Renhong Yan et al.   SCIENCE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

(2020) Qihui Wang et al.   CELL

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Soluble angiotensin-converting enzyme 2: a potential approach for coronavirus infection therapy?

(2020) Daniel Batlle et al.   CLINICAL SCIENCE

The presence of SARS‐CoV‐2 RNA in the feces of COVID‐19 patients

(2020) Yifei Chen et al.   JOURNAL OF MEDICAL VIROLOGY

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

(2020) Markus Hoffmann et al.   MOLECULAR CELL

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

(2020) Yi Xu et al.   NATURE MEDICINE

SARS-CoV-2 productively infects human gut enterocytes

(2020) Mart M. Lamers et al.   SCIENCE

The protein expression profile of ACE2 in human tissues

(2020) Feria Hikmet et al.   Molecular Systems Biology

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

(2020) Xiangyang Chi et al.   SCIENCE

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

(2020) Donald J. Benton et al.   NATURE

Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2

(2020) Lili Wu et al.   Cell Discovery

Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models

(2020) Gan Wang et al.   CELL RESEARCH

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

(2020) Cong Xu et al.   Science Advances

TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein

(2013) A. Heurich et al.   JOURNAL OF VIROLOGY

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

(2012) Tatsuo Hashimoto et al.   NATURE

Angiotensin II revisited: new roles in inflammation, immunology and aging

(2010) Ariela Benigni et al.   EMBO Molecular Medicine

A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry

(2010) A. Shulla et al.   JOURNAL OF VIROLOGY

Efficient Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by the Transmembrane Protease TMPRSS2

(2010) S. Matsuyama et al.   JOURNAL OF VIROLOGY

A protein complex in the brush-border membrane explains a Hartnup disorder allele

(2008) Sonja Kowalczuk et al.   FASEB JOURNAL

Tissue-Specific Amino Acid Transporter Partners ACE2 and Collectrin Differentially Interact With Hartnup Mutations

(2008) Simone M.R. Camargo et al.   GASTROENTEROLOGY